IL61756A - Anti-cancer 2-amino-4 hydroxy quinazoline methylamino-benzamide derivatives,process for their preparation and pharmaceutical compositions including them - Google Patents

Anti-cancer 2-amino-4 hydroxy quinazoline methylamino-benzamide derivatives,process for their preparation and pharmaceutical compositions including them

Info

Publication number
IL61756A
IL61756A IL61756A IL6175680A IL61756A IL 61756 A IL61756 A IL 61756A IL 61756 A IL61756 A IL 61756A IL 6175680 A IL6175680 A IL 6175680A IL 61756 A IL61756 A IL 61756A
Authority
IL
Israel
Prior art keywords
methylamino
cancer
amino
preparation
pharmaceutical compositions
Prior art date
Application number
IL61756A
Other languages
English (en)
Other versions
IL61756A0 (en
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of IL61756A0 publication Critical patent/IL61756A0/xx
Publication of IL61756A publication Critical patent/IL61756A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL61756A 1979-12-19 1980-12-18 Anti-cancer 2-amino-4 hydroxy quinazoline methylamino-benzamide derivatives,process for their preparation and pharmaceutical compositions including them IL61756A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7943715 1979-12-19
GB8006813 1980-02-28

Publications (2)

Publication Number Publication Date
IL61756A0 IL61756A0 (en) 1981-01-30
IL61756A true IL61756A (en) 1987-02-27

Family

ID=26273917

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61756A IL61756A (en) 1979-12-19 1980-12-18 Anti-cancer 2-amino-4 hydroxy quinazoline methylamino-benzamide derivatives,process for their preparation and pharmaceutical compositions including them

Country Status (17)

Country Link
US (2) US4447608A (da)
EP (1) EP0031237B1 (da)
AU (1) AU543237B2 (da)
CA (1) CA1184900A (da)
DE (1) DE3069468D1 (da)
DK (1) DK157019C (da)
ES (3) ES8300716A1 (da)
FI (1) FI76791C (da)
GB (1) GB2065653B (da)
GR (1) GR72847B (da)
HU (1) HU193505B (da)
IE (1) IE51188B1 (da)
IL (1) IL61756A (da)
NO (1) NO154919C (da)
NZ (1) NZ195876A (da)
PT (1) PT72232B (da)
YU (1) YU321180A (da)

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US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
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US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US5160727A (en) * 1990-02-13 1992-11-03 Warner-Lambert Company Tumor cell sensitization method using quinazolinedione derivatives
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
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US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9013615D0 (en) 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
US5145854A (en) * 1991-11-27 1992-09-08 Nair Madhavan G 1-formyl-5,8,10-trideazafolates
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
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US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
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GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
US5821231A (en) * 1993-12-06 1998-10-13 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using same
EP0737204A4 (en) * 1993-12-06 1999-06-23 Cytel Corp CS - 1 peptide mimetics, compositions and methods of their use
WO1995015973A1 (en) * 1993-12-06 1995-06-15 Cytel Corporation Cs-1 peptidomimetics, compositions and methods of using the same
US5770573A (en) * 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US5804396A (en) * 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
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US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
DE69729954T2 (de) * 1996-12-11 2005-09-08 Sugen, Inc., San Francisco Identifizierungsverfahren für Substanzen die an das Pyk2 Polypeptid binden
US6818440B2 (en) 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
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US6683113B2 (en) 1999-09-23 2004-01-27 Pharmacia Corporation (R)-chiral halogenated substituted N,N-Bis-benzyl aminioalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
EP1222273A2 (en) 1999-10-22 2002-07-17 PHARMACIA & UPJOHN COMPANY Drosophila g protein coupled receptors, nucleic acids, and methods related to the same
US7364866B2 (en) * 1999-10-22 2008-04-29 Pharmacia & Upjohn Company Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
US20030162223A1 (en) * 1999-10-22 2003-08-28 Lowery David E. Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
EP1237909A2 (en) * 1999-11-16 2002-09-11 PHARMACIA & UPJOHN COMPANY Human g protein-coupled receptors
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US6143776A (en) * 2000-02-02 2000-11-07 Sunesis Pharmaceuticals, Inc. Tosylproline analogs as thymidylate synthase inhibitors
US20030003451A1 (en) * 2000-02-23 2003-01-02 Gabriel Vogeli Novel G protein-coupled receptors
US20030027308A1 (en) * 2000-05-30 2003-02-06 Sugen Incorporated Novel human protein phosphatases identified from genomic sequencing
CA2321345A1 (fr) * 2000-10-02 2002-04-02 Abdelbast Guerfi Utilisation du graphite dans un composite pour reduire l'accumulation de glace
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WO2003020300A1 (en) 2001-08-31 2003-03-13 Btg International Limited Use of cyclopenta[g]quinazoline derivatives for treating cancer
JP2005509418A (ja) * 2001-11-13 2005-04-14 スージェン・インコーポレーテッド 哺乳動物蛋白質ホスファターゼ
US7537774B2 (en) * 2005-12-23 2009-05-26 Orion Therapeautics, Llc Therapeutic formulation
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GB1021196A (en) * 1964-02-20 1966-03-02 Parke Davis & Co Novel amino acids and means for producing the same
US3471498A (en) * 1967-08-11 1969-10-07 Parke Davis & Co Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids

Also Published As

Publication number Publication date
ES8308314A1 (es) 1983-09-01
FI76791C (fi) 1988-12-12
ES8307762A1 (es) 1983-08-01
US4447608A (en) 1984-05-08
NO803868L (no) 1981-06-22
US4564616A (en) 1986-01-14
IE51188B1 (en) 1986-10-29
ES497884A0 (es) 1982-11-01
EP0031237A1 (en) 1981-07-01
AU6549580A (en) 1981-06-25
GR72847B (da) 1983-12-07
DK157019C (da) 1990-03-26
GB2065653A (en) 1981-07-01
IL61756A0 (en) 1981-01-30
ES508454A0 (es) 1983-08-01
DK540080A (da) 1981-06-20
IE802672L (en) 1981-06-19
PT72232B (en) 1981-11-02
DK157019B (da) 1989-10-30
FI76791B (fi) 1988-08-31
NO154919C (no) 1987-01-14
GB2065653B (en) 1983-03-09
CA1184900A (en) 1985-04-02
ES8300716A1 (es) 1982-11-01
FI803957L (fi) 1981-06-20
DE3069468D1 (en) 1984-11-22
EP0031237B1 (en) 1984-10-17
YU321180A (en) 1983-06-30
HU193505B (en) 1987-10-28
ES508453A0 (es) 1983-09-01
PT72232A (en) 1981-01-01
AU543237B2 (en) 1985-04-04
NO154919B (no) 1986-10-06
NZ195876A (en) 1983-11-18

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