GR72847B - - Google Patents

Info

Publication number
GR72847B
GR72847B GR63713A GR800163713A GR72847B GR 72847 B GR72847 B GR 72847B GR 63713 A GR63713 A GR 63713A GR 800163713 A GR800163713 A GR 800163713A GR 72847 B GR72847 B GR 72847B
Authority
GR
Greece
Application number
GR63713A
Inventor
Terence Richard Jones
Kenneth Reginald Harrap
Alan Hilary Calvert
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of GR72847B publication Critical patent/GR72847B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR63713A 1979-12-19 1980-12-18 GR72847B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7943715 1979-12-19
GB8006813 1980-02-28

Publications (1)

Publication Number Publication Date
GR72847B true GR72847B (el) 1983-12-07

Family

ID=26273917

Family Applications (1)

Application Number Title Priority Date Filing Date
GR63713A GR72847B (el) 1979-12-19 1980-12-18

Country Status (17)

Country Link
US (2) US4447608A (el)
EP (1) EP0031237B1 (el)
AU (1) AU543237B2 (el)
CA (1) CA1184900A (el)
DE (1) DE3069468D1 (el)
DK (1) DK157019C (el)
ES (3) ES497884A0 (el)
FI (1) FI76791C (el)
GB (1) GB2065653B (el)
GR (1) GR72847B (el)
HU (1) HU193505B (el)
IE (1) IE51188B1 (el)
IL (1) IL61756A (el)
NO (1) NO154919C (el)
NZ (1) NZ195876A (el)
PT (1) PT72232B (el)
YU (1) YU321180A (el)

Families Citing this family (73)

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US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
GB8513754D0 (en) 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives
US5187167A (en) * 1986-03-27 1993-02-16 Imperial Chemical Industries Plc Pharmaceutical compositions comprising quinazolin-4-one derivatives
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5223620A (en) * 1988-04-01 1993-06-29 Takeda Chemical Industries, Ltd. Pyrido[2,3-d]pyrimidine compounds useful as intermediates
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US4996206A (en) * 1989-12-11 1991-02-26 The Trustees Of Princeton University N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives
US5160727A (en) * 1990-02-13 1992-11-03 Warner-Lambert Company Tumor cell sensitization method using quinazolinedione derivatives
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
IL98167A0 (en) * 1990-05-30 1992-06-21 Ici Plc Anti-tumour quinazoline derivatives,processes for their preparation and pharmaceutical compositions comprising them
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
US5145854A (en) * 1991-11-27 1992-09-08 Nair Madhavan G 1-formyl-5,8,10-trideazafolates
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
CH684644A5 (de) * 1992-07-13 1994-11-15 Eprova Ag 5,10-Methylentetrahydrofolsäure-Cyclodextrin-Einschlussverbindungen.
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
US5770573A (en) * 1993-12-06 1998-06-23 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
NZ277206A (en) * 1993-12-06 1997-11-24 Cytel Corp Peptide inhibiting binding of vlh-4 receptor expressed in inflammatory leukocytes and fibronectin cs-1 peptide expressed on endothelial cells involved in inflammatory disease states
US5821231A (en) * 1993-12-06 1998-10-13 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using same
AU693143B2 (en) * 1993-12-06 1998-06-25 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US5804396A (en) * 1994-10-12 1998-09-08 Sugen, Inc. Assay for agents active in proliferative disorders
US5837524A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polynucleotide products
US5837815A (en) * 1994-12-15 1998-11-17 Sugen, Inc. PYK2 related polypeptide products
US5593999A (en) * 1995-06-07 1997-01-14 Nair; Madhavan G. Non-classical folate analogue inhibitors of glycinamide ribonucleotide formyltransferase (GARFT)
WO1996040648A1 (en) * 1995-06-07 1996-12-19 Sugen, Inc. Quinazolines and pharmaceutical compositions
US6716575B2 (en) 1995-12-18 2004-04-06 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
US7119174B2 (en) * 1995-12-18 2006-10-10 Sugen, Inc. Diagnosis and treatment of AUR1 and/or AUR2 related disorders
ATE271603T1 (de) * 1996-12-11 2004-08-15 Sugen Inc Identifizierungsverfahren für substanzen die an das pyk2 polypeptid binden
US6818440B2 (en) * 1997-04-28 2004-11-16 Sugen, Inc. Diagnosis and treatment of alk-7 related disorders
US6228641B1 (en) 1997-05-20 2001-05-08 Sugen, Inc. Diagnosis and treatment of PTP04 related disorders
US7115710B2 (en) * 1997-06-11 2006-10-03 Sugen, Inc. Diagnosis and treatment of PTP related disorders
US6342593B1 (en) 1997-06-11 2002-01-29 Sugen, Inc. Diagnosis and treatment of ALP related disorders
US6388063B1 (en) 1997-06-18 2002-05-14 Sugen, Inc. Diagnosis and treatment of SAD related disorders
EP1049786A2 (en) * 1998-01-21 2000-11-08 Sugen, Inc. Human orthologues of wart
DE69926742T2 (de) * 1998-04-14 2006-06-14 Sugen Inc Ste20-verwandte proteinkinasen
US6861442B1 (en) 1998-12-30 2005-03-01 Sugen, Inc. PYK2 and inflammation
GB9904275D0 (en) 1999-02-24 1999-04-21 Cancer Res Campaign Tech Anti-cancer compounds
US6677382B1 (en) 1999-09-23 2004-01-13 Pharmacia Corporation Substituted N,N-bis-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
US6723752B2 (en) 1999-09-23 2004-04-20 Pharmacia Corporation (R)-chiral halogenated substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
US6451830B1 (en) 1999-09-23 2002-09-17 G.D. Searle & Co. Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity
US7364866B2 (en) * 1999-10-22 2008-04-29 Pharmacia & Upjohn Company Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
JP2003512838A (ja) * 1999-10-22 2003-04-08 ファルマシア・アンド・アップジョン・カンパニー ショウジョウバエｇタンパク質結合レセプター、核酸、およびそれに関連する方法。
US20030162223A1 (en) * 1999-10-22 2003-08-28 Lowery David E. Drosophila G protein coupled receptors, nucleic acids, and methods related to the same
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
US20030082534A1 (en) * 1999-11-16 2003-05-01 Peter Lind Novel G protein-coupled receptors
US6143776A (en) * 2000-02-02 2000-11-07 Sunesis Pharmaceuticals, Inc. Tosylproline analogs as thymidylate synthase inhibitors
EP1265925A2 (en) * 2000-02-23 2002-12-18 PHARMACIA & UPJOHN COMPANY G protein-coupled receptors
US20030027308A1 (en) * 2000-05-30 2003-02-06 Sugen Incorporated Novel human protein phosphatases identified from genomic sequencing
CA2321345A1 (fr) * 2000-10-02 2002-04-02 Abdelbast Guerfi Utilisation du graphite dans un composite pour reduire l'accumulation de glace
US20040157306A1 (en) * 2000-11-13 2004-08-12 Sugen Incorporated Mammalian protein phosphatases
US20050069976A1 (en) * 2001-02-14 2005-03-31 Peter Lind Protein-coupled receptor
EP2332962A1 (en) 2001-08-31 2011-06-15 BTG International Limited Cyclopenta[g]quinazoline compounds for use in the treatment of inflammatory or allergic conditions
ATE526028T1 (de) 2001-08-31 2011-10-15 Btg Int Ltd Verwendung von cyclopentaägüchinazoline-derivaten zur krebsbehandlung
JP2005509418A (ja) * 2001-11-13 2005-04-14 スージェン・インコーポレーテッド 哺乳動物蛋白質ホスファターゼ
US7537774B2 (en) * 2005-12-23 2009-05-26 Orion Therapeautics, Llc Therapeutic formulation
SG177225A1 (en) * 2006-12-01 2012-01-30 Agency Science Tech & Res Cancer-related protein kinases
JP5693950B2 (ja) 2007-04-11 2015-04-01 メルク エ カンパニー １８ｆ標識葉酸
US8273617B2 (en) 2009-09-30 2012-09-25 Suvolta, Inc. Electronic devices and systems, and methods for making and using the same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1021196A (en) * 1964-02-20 1966-03-02 Parke Davis & Co Novel amino acids and means for producing the same
US3471498A (en) * 1967-08-11 1969-10-07 Parke Davis & Co Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids

Also Published As

Publication number Publication date
FI803957L (fi) 1981-06-20
CA1184900A (en) 1985-04-02
NO154919B (no) 1986-10-06
DK157019C (da) 1990-03-26
NO803868L (no) 1981-06-22
ES8300716A1 (es) 1982-11-01
ES8308314A1 (es) 1983-09-01
NZ195876A (en) 1983-11-18
HU193505B (en) 1987-10-28
FI76791B (fi) 1988-08-31
DK157019B (da) 1989-10-30
DE3069468D1 (en) 1984-11-22
ES508453A0 (es) 1983-09-01
AU543237B2 (en) 1985-04-04
IL61756A0 (en) 1981-01-30
DK540080A (da) 1981-06-20
PT72232A (en) 1981-01-01
GB2065653A (en) 1981-07-01
PT72232B (en) 1981-11-02
EP0031237A1 (en) 1981-07-01
US4564616A (en) 1986-01-14
IE51188B1 (en) 1986-10-29
ES497884A0 (es) 1982-11-01
EP0031237B1 (en) 1984-10-17
NO154919C (no) 1987-01-14
IE802672L (en) 1981-06-19
ES8307762A1 (es) 1983-08-01
ES508454A0 (es) 1983-08-01
GB2065653B (en) 1983-03-09
US4447608A (en) 1984-05-08
AU6549580A (en) 1981-06-25
YU321180A (en) 1983-06-30
IL61756A (en) 1987-02-27
FI76791C (fi) 1988-12-12

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