IL60095A - Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen - Google Patents
Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophenInfo
- Publication number
- IL60095A IL60095A IL60095A IL6009580A IL60095A IL 60095 A IL60095 A IL 60095A IL 60095 A IL60095 A IL 60095A IL 6009580 A IL6009580 A IL 6009580A IL 60095 A IL60095 A IL 60095A
- Authority
- IL
- Israel
- Prior art keywords
- nalbuphine
- acetaminophen
- pharmaceutical compositions
- analgesic pharmaceutical
- synergistic analgesic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/040,281 US4237140A (en) | 1979-05-18 | 1979-05-18 | Analgesic mixture of nalbuphine and acetaminophen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL60095A0 IL60095A0 (en) | 1980-07-31 |
IL60095A true IL60095A (en) | 1982-12-31 |
Family
ID=21910135
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL60095A IL60095A (en) | 1979-05-18 | 1980-05-16 | Synergistic analgesic pharmaceutical compositions comprising nalbuphine and acetaminophen |
Country Status (12)
Country | Link |
---|---|
US (1) | US4237140A (de) |
EP (1) | EP0019282B1 (de) |
JP (1) | JPS55154917A (de) |
AU (1) | AU529764B2 (de) |
CA (1) | CA1139671A (de) |
DE (1) | DE3061597D1 (de) |
HU (1) | HU178867B (de) |
IE (1) | IE49988B1 (de) |
IL (1) | IL60095A (de) |
NZ (1) | NZ193695A (de) |
PH (1) | PH15265A (de) |
ZA (1) | ZA802916B (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4322427A (en) * | 1981-04-16 | 1982-03-30 | Bristol-Myers Company | Analgetic compositions and methods of use |
US4366159A (en) * | 1981-09-08 | 1982-12-28 | Michael Richard Magruder | Nalbuphine-narcotic analgesic composition and method of producing analgesia |
US4404208A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and tiflamizole |
US4404211A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and flurbiprofen |
US4404210A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and ibuprofen |
US4407804A (en) * | 1982-06-30 | 1983-10-04 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and indomethacin |
US4404209A (en) * | 1982-06-30 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and sulindac |
US4407805A (en) * | 1982-06-30 | 1983-10-04 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and zomepirac |
US4402962A (en) * | 1982-06-30 | 1983-09-06 | E. I. Du Pont De Nemours And Company | Analgesic mixture of nalbuphine and 4,5-bis(4-methoxyphenyl)-2-(trifluoromethylsulfonyl)-1H-imidazole |
AU565634B2 (en) * | 1982-06-30 | 1987-09-24 | E.I. Du Pont De Nemours And Company | Synergistic compositions of nalbuphine and non-narcotic analgesic compounds |
US4656177A (en) * | 1982-07-22 | 1987-04-07 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
JPS59501460A (ja) * | 1982-07-22 | 1984-08-16 | サンシヤイン,アブラハム | カフェインを含んで成る改良された鎮痛及び抗炎症組成物並びにその使用方法 |
US4777174A (en) * | 1982-07-22 | 1988-10-11 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
US4722928A (en) * | 1985-12-02 | 1988-02-02 | E. I. Du Pont De Nemours And Company | N-oxide prodrug derivatives of 3-hydroxy morphinans and partial morphinans having improved oral bioavailability, pharmaceutical compositions, and processes |
KR100243956B1 (ko) | 1991-09-06 | 2000-03-02 | 랄프 알. 팔로 | 트라마돌 물질 및 아세트아미노펜을 포함하는 통증 치료용 약제학적 조성물 |
US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
US6348216B1 (en) * | 1996-06-10 | 2002-02-19 | Knoll Pharmaceutical Company | Ibuprofen and narcotic analgesic compositions |
US6361794B1 (en) | 1996-06-12 | 2002-03-26 | Basf Corporation | Method of making ibuprofen and narcotic analgesic composition |
US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
SI1685839T1 (sl) | 1997-12-22 | 2013-08-30 | Euro-Celtique S.A. | Farmacevtska oralna dozirna oblika, ki vsebuje kombinacijo opioidnega agonista in opioidnega antagonista |
NZ520554A (en) * | 2000-02-08 | 2005-08-26 | Euro Celtique S | Tamper-resistant oral opioid agonist formulations |
CN1525851A (zh) | 2001-05-11 | 2004-09-01 | ������ҩ������˾ | 抗滥用阿片样物质控释剂型 |
DK1416842T3 (da) | 2001-07-18 | 2009-03-16 | Euro Celtique Sa | Farmaceutiske kombinationer af oxycodon og naloxon |
US20030044458A1 (en) | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
DE60232417D1 (de) | 2001-08-06 | 2009-07-02 | Euro Celtique Sa | Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist |
US20030157168A1 (en) | 2001-08-06 | 2003-08-21 | Christopher Breder | Sequestered antagonist formulations |
KR20040098050A (ko) | 2002-04-05 | 2004-11-18 | 유로-셀띠끄 소시에떼 아노님 | 옥시코돈 및 날록손을 포함하는 약제학적 제제 |
PT1551372T (pt) | 2002-09-20 | 2018-07-23 | Alpharma Pharmaceuticals Llc | Subunidade de sequestração e composições e métodos relacionados |
US20040202717A1 (en) | 2003-04-08 | 2004-10-14 | Mehta Atul M. | Abuse-resistant oral dosage forms and method of use thereof |
TWI347201B (en) | 2003-04-21 | 2011-08-21 | Euro Celtique Sa | Pharmaceutical products,uses thereof and methods for preparing the same |
EP1604666A1 (de) | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit |
EP1702558A1 (de) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Verfahren und Vorrichtung zur Darmtätigkeitserfassung |
US8394812B2 (en) | 2005-08-24 | 2013-03-12 | Penwest Pharmaceuticals Co. | Sustained release formulations of nalbuphine |
EP1931315B1 (de) * | 2005-08-24 | 2013-10-16 | Penwest Pharmaceuticals Co. | Nalbuphin-formulierungen mit verzögerter freisetzung |
US8158156B2 (en) | 2006-06-19 | 2012-04-17 | Alpharma Pharmaceuticals, Llc | Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist |
US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
EP2405915B1 (de) | 2009-03-10 | 2018-10-24 | Euro-Celtique S.A. | Unmittelbare freisetzung pharmazeutischer zusammensetzungen mit oxycodon und naloxon |
NZ716267A (en) | 2013-07-23 | 2017-05-26 | Euro Celtique Sa | A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
KR20240051283A (ko) | 2013-12-24 | 2024-04-19 | 버지니아 커먼웰스 유니버시티 | 산소첨가된 콜레스테롤 술페이트 (ocs) 의 용도 |
US11260048B2 (en) | 2017-10-03 | 2022-03-01 | The Schepens Eye Research Institute, Inc. | Compounds and compositions for inhibiting retinal pigment epithelium degeneration and methods using the same |
EP3846815A4 (de) * | 2018-09-03 | 2022-05-04 | Jacob Biotech Ltd | Pharmazeutische zubereitungen von sebacoyl-dinalbuphin und acetaminophen und verfahren zur schmerzbehandlung |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL26896A (en) * | 1966-01-19 | 1970-11-30 | Endo Lab | 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones |
US4029798A (en) * | 1975-06-02 | 1977-06-14 | Sumitomo Chemical Company, Limited | Analgetic composition |
JPS5946205B2 (ja) * | 1976-01-01 | 1984-11-10 | 科研製薬株式会社 | ベンゾイル誘導体を有効成分とする消炎鎮痛剤 |
-
1979
- 1979-05-18 US US06/040,281 patent/US4237140A/en not_active Expired - Lifetime
-
1980
- 1980-05-13 NZ NZ193695A patent/NZ193695A/en unknown
- 1980-05-13 AU AU58351/80A patent/AU529764B2/en not_active Ceased
- 1980-05-15 DE DE8080102696T patent/DE3061597D1/de not_active Expired
- 1980-05-15 CA CA000352011A patent/CA1139671A/en not_active Expired
- 1980-05-15 EP EP80102696A patent/EP0019282B1/de not_active Expired
- 1980-05-16 IL IL60095A patent/IL60095A/xx unknown
- 1980-05-16 HU HU80801223A patent/HU178867B/hu not_active IP Right Cessation
- 1980-05-16 IE IE1019/80A patent/IE49988B1/en not_active IP Right Cessation
- 1980-05-16 ZA ZA00802916A patent/ZA802916B/xx unknown
- 1980-05-16 PH PH24035A patent/PH15265A/en unknown
- 1980-05-17 JP JP6469980A patent/JPS55154917A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
AU5835180A (en) | 1980-11-20 |
JPS55154917A (en) | 1980-12-02 |
AU529764B2 (en) | 1983-06-16 |
IL60095A0 (en) | 1980-07-31 |
DE3061597D1 (en) | 1983-02-17 |
EP0019282A1 (de) | 1980-11-26 |
NZ193695A (en) | 1984-05-31 |
PH15265A (en) | 1982-11-02 |
IE49988B1 (en) | 1986-01-22 |
US4237140A (en) | 1980-12-02 |
CA1139671A (en) | 1983-01-18 |
HU178867B (en) | 1982-07-28 |
JPH0144684B2 (de) | 1989-09-29 |
IE801019L (en) | 1980-11-18 |
EP0019282B1 (de) | 1983-01-12 |
ZA802916B (en) | 1981-12-30 |
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