IL58526A - 24,24-difluoro-1alpha,25-dihydroxycholecalciferol and pharmaceutical compositions containing it - Google Patents

24,24-difluoro-1alpha,25-dihydroxycholecalciferol and pharmaceutical compositions containing it

Info

Publication number
IL58526A
IL58526A IL58526A IL5852679A IL58526A IL 58526 A IL58526 A IL 58526A IL 58526 A IL58526 A IL 58526A IL 5852679 A IL5852679 A IL 5852679A IL 58526 A IL58526 A IL 58526A
Authority
IL
Israel
Prior art keywords
dihydroxycholecalciferol
1alpha
difluoro
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL58526A
Other languages
English (en)
Other versions
IL58526A0 (en
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of IL58526A0 publication Critical patent/IL58526A0/xx
Publication of IL58526A publication Critical patent/IL58526A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/48Halogenated derivatives
    • C07C35/52Alcohols with a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/24All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL58526A 1979-03-28 1979-10-22 24,24-difluoro-1alpha,25-dihydroxycholecalciferol and pharmaceutical compositions containing it IL58526A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/024,848 US4201881A (en) 1979-03-28 1979-03-28 24,24-Difluoro-1α,25-dihydroxycholecalciferol

Publications (2)

Publication Number Publication Date
IL58526A0 IL58526A0 (en) 1980-01-31
IL58526A true IL58526A (en) 1983-05-15

Family

ID=21822707

Family Applications (1)

Application Number Title Priority Date Filing Date
IL58526A IL58526A (en) 1979-03-28 1979-10-22 24,24-difluoro-1alpha,25-dihydroxycholecalciferol and pharmaceutical compositions containing it

Country Status (15)

Country Link
US (1) US4201881A (da)
JP (2) JPS6342618B2 (da)
AU (1) AU530015B2 (da)
BE (1) BE882143A (da)
CH (1) CH650240A5 (da)
DK (1) DK147300C (da)
FR (1) FR2452481A1 (da)
GB (2) GB2067567B (da)
IE (1) IE49753B1 (da)
IL (1) IL58526A (da)
IT (1) IT1140776B (da)
NL (1) NL7920190A (da)
NZ (1) NZ191900A (da)
SE (1) SE8008339L (da)
WO (1) WO1980002028A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same
DE3268960D1 (en) * 1981-08-28 1986-03-20 Hoffmann La Roche Cholecalciferol derivatives
EP0094644B1 (de) * 1982-05-17 1986-07-30 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verwendung eines Cholecalciferolderivates
US4456689A (en) * 1982-05-17 1984-06-26 Becton Dickinson And Company Competitive protein binding assay using an organosilane-silica gel separation medium
US4428946A (en) * 1982-07-26 1984-01-31 Wisconsin Alumni Research Foundation Method of preventing milk fever in dairy cattle
JPS6253960A (ja) * 1985-05-30 1987-03-09 Taisho Pharmaceut Co Ltd ビタミンd↓3の誘導体
EP0245524B1 (en) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Vitamin d 3 derivative
US4853378A (en) * 1986-10-20 1989-08-01 Sumitomo Chemical Company, Limited Fluorine derivatives of vitamin D3 and process for producing the same
WO1990009179A1 (en) * 1989-02-16 1990-08-23 University Of Georgia Research Foundation, Inc. Treatment of tibial dyschondroplasia
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5316770A (en) * 1989-02-16 1994-05-31 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
US5063234A (en) * 1990-05-25 1991-11-05 Eli Lilly And Company Method of inhibiting demineralization of bone
JP2011508743A (ja) * 2007-12-28 2011-03-17 ウィスコンシン アラムナイ リサーチ ファンデーション (20s)−23,23−ジフルオロ−2−メチレン−19−ノル−ビスホモプレグナカルシフェロール−ビタミンd類縁体
JP5504898B2 (ja) * 2010-01-08 2014-05-28 セントラル硝子株式会社 ジフルオロシクロプロパン化合物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol
FR2267590B1 (da) * 1974-04-10 1977-05-20 Ibm
US3969700A (en) * 1974-04-10 1976-07-13 International Business Machines Corporation Regional context maximum likelihood error correction for OCR, keyboard, and the like
JPS5729745B2 (da) * 1974-09-25 1982-06-24
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4284577A (en) * 1979-02-16 1981-08-18 Sachiko Yamada Novel vitamin D3 derivative and process for preparing the same

Also Published As

Publication number Publication date
NZ191900A (en) 1984-11-09
BE882143A (fr) 1980-07-01
DK147300C (da) 1984-12-24
IE800619L (en) 1980-09-28
AU530015B2 (en) 1983-06-30
JPS63179855A (ja) 1988-07-23
SE8008339L (sv) 1980-11-27
GB2067567A (en) 1981-07-30
DK147300B (da) 1984-06-12
IL58526A0 (en) 1980-01-31
US4201881A (en) 1980-05-06
IT8020508A0 (it) 1980-03-11
CH650240A5 (de) 1985-07-15
FR2452481A1 (fr) 1980-10-24
WO1980002028A1 (en) 1980-10-02
IT1140776B (it) 1986-10-10
GB2067567B (en) 1983-03-02
NL7920190A (nl) 1981-01-30
AU5581080A (en) 1980-10-02
JPS56500296A (da) 1981-03-12
FR2452481B1 (da) 1984-10-19
GB2045765A (en) 1980-11-05
DK505080A (da) 1980-11-27
GB2045765B (en) 1983-06-15
IE49753B1 (en) 1985-12-11
JPS6342618B2 (da) 1988-08-24
JPH0146504B2 (da) 1989-10-09

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