IL56077A - Pharmaceutically acceptable particles comprising a clavulanic acid salt,their preparation and pharmaceutical compositions containing them - Google Patents

Pharmaceutically acceptable particles comprising a clavulanic acid salt,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL56077A
IL56077A IL56077A IL5607778A IL56077A IL 56077 A IL56077 A IL 56077A IL 56077 A IL56077 A IL 56077A IL 5607778 A IL5607778 A IL 5607778A IL 56077 A IL56077 A IL 56077A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutically acceptable
pharmaceutical compositions
acid salt
compositions containing
Prior art date
Application number
IL56077A
Other languages
English (en)
Other versions
IL56077A0 (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of IL56077A0 publication Critical patent/IL56077A0/xx
Publication of IL56077A publication Critical patent/IL56077A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL56077A 1977-12-08 1978-11-29 Pharmaceutically acceptable particles comprising a clavulanic acid salt,their preparation and pharmaceutical compositions containing them IL56077A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5105877 1977-12-08

Publications (2)

Publication Number Publication Date
IL56077A0 IL56077A0 (en) 1979-01-31
IL56077A true IL56077A (en) 1981-09-13

Family

ID=10458491

Family Applications (1)

Application Number Title Priority Date Filing Date
IL56077A IL56077A (en) 1977-12-08 1978-11-29 Pharmaceutically acceptable particles comprising a clavulanic acid salt,their preparation and pharmaceutical compositions containing them

Country Status (12)

Country Link
US (1) US4223006A (da)
EP (1) EP0002574B1 (da)
JP (1) JPS54113419A (da)
AU (1) AU522918B2 (da)
CA (1) CA1132048A (da)
DE (1) DE2862210D1 (da)
DK (1) DK532078A (da)
IE (1) IE47687B1 (da)
IL (1) IL56077A (da)
NZ (1) NZ189022A (da)
PH (1) PH15215A (da)
ZA (1) ZA786694B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4758437A (en) * 1981-12-23 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Composition for long acting nicardipine preparation and process of producing the composition
DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4828882A (en) * 1987-03-16 1989-05-09 Canadian Patents & Developments Limited Particle encapsulation technique
GB9416600D0 (en) * 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
GB2309017A (en) * 1995-12-20 1997-07-16 Remi Oseri Cornwall Particles of hygroscopic substances having water-permeable shells for use in physical phase-changing device
WO1998024410A2 (en) * 1996-12-03 1998-06-11 Schering-Plough Kabushiki Kaisha Controlled release matrix tablet and method for its preparation
WO1999025343A1 (en) * 1997-11-17 1999-05-27 Gist-Brocades B.V. Granules comprising clavulanate and one or more excipients
MXPA01009808A (es) * 1999-04-01 2002-04-24 Dsm Nv Aglomerados por cristalizacion.
ATE518540T1 (de) * 1999-08-16 2011-08-15 Revaax Pharmaceuticals Llc Beta-lactam verbindung enthaltende neurotherapeutische zusammensetzung
US6426342B2 (en) * 1999-08-16 2002-07-30 Revaax Pharmaceuticals, Llc Use of β-lactamase inhibitors as neuroprotectants
MXPA03003312A (es) * 2000-10-20 2004-12-03 Biochemie Gmbh Composiciones farmaceuticas.
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
KR20100101574A (ko) * 2007-10-26 2010-09-17 렉산 파마슈티컬스, 인코포레이티드 클라불란산의 제약 제제
CN102413814A (zh) * 2009-04-29 2012-04-11 瑞恩药品公司 用于神经保护和治疗神经变性病症的克拉维酸类物质制剂
AU2017295866A1 (en) 2016-07-14 2019-01-17 Achaogen, Inc. Combination of ceftibuten and clavulanic acid for use in the treatment of bacterial infections

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2410417A (en) * 1944-03-04 1946-11-05 Lever Brothers Ltd Vitamin and mineral dietary supplement and method of making
US2811483A (en) * 1954-12-09 1957-10-29 Pfizer & Co C Pharmaceutical composition and process for preparing the same
BE590276A (da) * 1959-04-30
GB978264A (da) * 1960-02-26
US3400185A (en) * 1965-04-08 1968-09-03 Bristol Myers Co Agglomeration of smaller pharmaceutical particles into larger microspherules and enteic-coating thereof
DE1492034A1 (de) * 1965-05-18 1969-02-20 Merck Ag E Verfahren zur Herstellung fester haltbarer Zubereitungen von empfindlichen,in Wasser schwer loeslichen Wirkstoffen,vorzugsweise Arzneimitteln
US3553313A (en) * 1966-12-21 1971-01-05 Luis Picas Tort Manufacture of granulate feed
ZA718014B (en) * 1970-12-23 1972-08-30 Beecham Group Ltd Pharmaceutical formulations
US3909444A (en) * 1971-08-05 1975-09-30 Ncr Co Microcapsule
US4016254A (en) * 1972-05-19 1977-04-05 Beecham Group Limited Pharmaceutical formulations
BE791458A (fr) * 1972-07-31 1973-05-16 Merck & Co Inc Produit microencapsule
DE2406625C3 (de) * 1973-02-27 1979-11-08 Zenyaku Kogyo K.K., Tokio Verfahren zum Überziehen von festen Teilchen mit einem im Verdauungstrakt löslichen Film und Vorrichtung zu seiner Durchführung
US4123382A (en) * 1973-05-25 1978-10-31 Merck & Co., Inc. Method of microencapsulation
GB1479655A (en) * 1974-03-08 1977-07-13 Beecham Group Ltd Antibiotic preparations
GB1529913A (en) * 1976-02-04 1978-10-25 Beecham Group Ltd Beta-lactam compounds

Also Published As

Publication number Publication date
IL56077A0 (en) 1979-01-31
IE782422L (en) 1979-06-08
AU4236178A (en) 1979-06-21
JPS54113419A (en) 1979-09-05
DE2862210D1 (en) 1983-04-28
ZA786694B (en) 1979-10-31
IE47687B1 (en) 1984-05-30
EP0002574B1 (en) 1983-03-23
US4223006A (en) 1980-09-16
CA1132048A (en) 1982-09-21
PH15215A (en) 1982-09-27
EP0002574A1 (en) 1979-06-27
AU522918B2 (en) 1982-07-01
DK532078A (da) 1979-06-09
NZ189022A (en) 1981-11-19

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