IL55894A - 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL55894A
IL55894A IL55894A IL5589478A IL55894A IL 55894 A IL55894 A IL 55894A IL 55894 A IL55894 A IL 55894A IL 5589478 A IL5589478 A IL 5589478A IL 55894 A IL55894 A IL 55894A
Authority
IL
Israel
Prior art keywords
alkylenedithia
oxathia
heteroaryl
benzyl
preparation
Prior art date
Application number
IL55894A
Other languages
English (en)
Other versions
IL55894A0 (en
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Publication of IL55894A0 publication Critical patent/IL55894A0/xx
Publication of IL55894A publication Critical patent/IL55894A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL55894A 1977-11-09 1978-11-08 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them IL55894A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4664677 1977-11-09

Publications (2)

Publication Number Publication Date
IL55894A0 IL55894A0 (en) 1979-01-31
IL55894A true IL55894A (en) 1981-09-13

Family

ID=10442057

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55894A IL55894A (en) 1977-11-09 1978-11-08 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US4260610A (fr)
JP (1) JPS5481284A (fr)
AR (3) AR220730A1 (fr)
AU (1) AU4140778A (fr)
BE (1) BE871857A (fr)
CA (1) CA1117944A (fr)
DE (1) DE2848139A1 (fr)
ES (1) ES474896A1 (fr)
FR (1) FR2408605A1 (fr)
IL (1) IL55894A (fr)
IT (1) IT1109266B (fr)
NL (1) NL7811135A (fr)
OA (1) OA06083A (fr)
ZA (1) ZA786262B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3902316A1 (de) * 1989-01-26 1990-08-02 Lentia Gmbh Neue piperazinylalkyl-3(2h)-pyridazinone, verfahren zu ihrer herstellung und ihre verwendung als blutdrucksenkende mittel
US4988699A (en) * 1989-03-14 1991-01-29 Warner-Lambert Company Substituted tetrahydrobenzothiazoles as dopaminergic agents
US4954503A (en) * 1989-09-11 1990-09-04 Hoechst-Roussel Pharmaceuticals, Inc. 3-(1-substituted-4-piperazinyl)-1H-indazoles
FR2671350A1 (fr) * 1991-01-08 1992-07-10 Adir Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant.
US5859246A (en) 1997-01-30 1999-01-12 Neurogen Corporation 1-phenyl-4-benzylpiperazines: dopamine receptor subtype specific ligands
RU2576037C1 (ru) * 2014-11-28 2016-02-27 Закрытое акционерное общество "Исследовательский институт Химического разнообразия" ЗАО "ИИХР" Замещенные 4-{ [4-(3,3-диоксидо-1,3-бензоксатиол-6-ил)арилокси]метил} пиперидины как агонисты рецепторов gpr119, фармацевтическая композиция, способы их получения и применения
KR20230110650A (ko) * 2016-06-09 2023-07-24 프라마나 파마슈티컬스 인크. 벤조[d][1,3]옥사티올, 벤조[d][1,3]옥사티올 3-옥사이드또는 벤조[d][1,3]옥사티올 3,3-디옥사이드를 함유하는 화합물 및 Ｇ 단백질 커플링된 수용체 119의 작용제로서 이의 방법/용도
WO2019104418A1 (fr) 2017-11-30 2019-06-06 Pramana Pharmaceuticals Inc. Composés contenant du benzo[d][1,3]oxathiole, benzo[d][1,3]oxathiole 3-oxyde ou du benzo[d][1,3]oxathiole 3,3-dioxyde polysubstitué, et leurs procédés/utilisations en tant qu'agonistes du récepteur 119 couplé à la protéine g

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2459367A (en) * 1947-11-12 1949-01-18 American Cyanamid Co 1,4-di (heterocyclic substituted) piperazines
US2561036A (en) * 1948-06-07 1951-07-17 Noel S Sodders Thread-cutting sheet metal nut
NL127996C (fr) * 1963-11-19
DE1595923A1 (de) * 1965-02-20 1969-11-27 Merck Ag E 1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung
GB1187680A (en) * 1967-11-15 1970-04-15 Science Union & Cie New Heterocyclic Substituted Piperazines
GB1407552A (en) * 1973-04-02 1975-09-24 Science Union & Cie Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them
GB1432660A (en) * 1973-10-30 1976-04-22 Science Union & Cie Piperazine derivatives processes for their preparation and and pharamacueitcal compositions containing them

Also Published As

Publication number Publication date
FR2408605A1 (fr) 1979-06-08
JPS5481284A (en) 1979-06-28
IT1109266B (it) 1985-12-16
AR220730A1 (es) 1980-11-28
NL7811135A (nl) 1979-05-11
OA06083A (fr) 1981-06-30
ZA786262B (en) 1979-10-31
BE871857A (fr) 1979-05-08
DE2848139A1 (de) 1979-05-10
JPS6136755B2 (fr) 1986-08-20
US4260610A (en) 1981-04-07
IL55894A0 (en) 1979-01-31
AU4140778A (en) 1979-05-17
CA1117944A (fr) 1982-02-09
AR220794A1 (es) 1980-11-28
ES474896A1 (es) 1979-03-16
IT7851814A0 (it) 1978-11-08
FR2408605B1 (fr) 1982-02-05
AR220793A1 (es) 1980-11-28

Similar Documents

Publication Publication Date Title
IL54842A (en) 1-piperidino-phthalazine derivatives,their preparation and pharmaceutical compositions containing them
DE2861316D1 (en) Thienothiazine derivatives, their preparation and compositions containing them
IL56155A (en) Substituted alkanoylanilide derivatives,their preparation and pharmaceutical compositions comprising them
IL56206A0 (en) New 1,2-benzothiazine-1,1-doxide derivatives, their preparation and pharmaceutical compositions containing them
IL53996A (en) 1-substituted-2-fluoroalkylthio-4,5-diphenyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL55845A (en) Quinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL56017A (en) 5-cyano-prostacyclin derivatives,their manufacture and pharmaceutical compositions containing them
IL55765A (en) Dehydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL56284A (en) 7-(2-thiazolyl-2-alkoxyiminoacetamido)-cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL54438A (en) Substituted anisole derivatives,their preparation and pharmaceutical compositions containing them
IL54535A0 (en) Novel -lactam derivatives, their preparation and pharmaceutical compositions containing them
IL53857A0 (en) New aminoalkoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL55813A0 (en) Movel triazile derivatives, their preparation and pharmaceutical compositions containing them
IL54814A (en) 5,11-dihydro-11(piperazin-1-yl-alkanoyl)-6h-pyrido(2,3-b) (1,4)benzoidiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them
IL55254A (en) Bis-isoquinolinium compounds,their preparation and pharmaceutical compositions containing them
IL55894A (en) 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
IL54547A0 (en) Novel pyridazinone derivatives, their preparation and pharmaceutical compositions containing them
IL55857A (en) Benzodioxanylcarbonyl-piperazinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL53766A0 (en) 4-diphenylmethylene-1-hydroxybenzyl-piperidine derivatives, their preparation and pharmaceutical compositions containing them
IL53861A0 (en) Novel n-aralkylaniline derivatives, their preparation and pharmaceutical compositions containing them
IL53904A (en) -phenyltolyl azacycloalkane or azacycloalkene derivatives,their preparation and pharmaceutical compositions comprising them
IL55095A0 (en) Novel piperidino-propanol derivatives,their preparation and pharmaceutical compositions containing them
IL55120A0 (en) New 3-pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL54899A (en) Pyridazinylhydrazones,their preparation and pharmaceutical compositions containing them
IL54677A (en) N1-carboxylic acyl-n2-phenyl-2-hydroxy-1,3-diaminopropane derivatives, their preparation and pharmaceutical compositions containing them