IL55844A - 1-piperidino phthalazines,their preparation and pharmaceutical compositions containing them - Google Patents
1-piperidino phthalazines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL55844A IL55844A IL55844A IL5584478A IL55844A IL 55844 A IL55844 A IL 55844A IL 55844 A IL55844 A IL 55844A IL 5584478 A IL5584478 A IL 5584478A IL 55844 A IL55844 A IL 55844A
- Authority
- IL
- Israel
- Prior art keywords
- phthalazines
- piperidino
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4567077 | 1977-11-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL55844A0 IL55844A0 (en) | 1979-01-31 |
| IL55844A true IL55844A (en) | 1982-05-31 |
Family
ID=10438118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL55844A IL55844A (en) | 1977-11-03 | 1978-11-01 | 1-piperidino phthalazines,their preparation and pharmaceutical compositions containing them |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS5498783A (fr) |
| AR (3) | AR219561A1 (fr) |
| AT (1) | AT365184B (fr) |
| AU (1) | AU507007B2 (fr) |
| BE (1) | BE871770A (fr) |
| CA (1) | CA1114379A (fr) |
| DE (1) | DE2847621A1 (fr) |
| DK (1) | DK487978A (fr) |
| ES (5) | ES474764A0 (fr) |
| FI (1) | FI783326A (fr) |
| FR (1) | FR2407927A1 (fr) |
| IE (1) | IE47481B1 (fr) |
| IL (1) | IL55844A (fr) |
| IT (1) | IT1101279B (fr) |
| LU (1) | LU80458A1 (fr) |
| NL (1) | NL7810864A (fr) |
| PH (1) | PH14659A (fr) |
| PT (1) | PT68734A (fr) |
| SE (1) | SE7811322L (fr) |
| YU (3) | YU253678A (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6215356U (fr) * | 1985-07-15 | 1987-01-29 | ||
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| WO2004099179A1 (fr) * | 2003-05-07 | 2004-11-18 | Actelion Pharmaceuticals Ltd | Derives de piperazine-alkyle-ureido |
| KR20080065704A (ko) | 2005-11-09 | 2008-07-14 | 콤비네이토릭스, 인코포레이티드 | 의학적 이상의 치료 방법들, 조성물들, 및 키트들 |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| EP3241839B1 (fr) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012118972A2 (fr) | 2011-03-01 | 2012-09-07 | Synegy Pharmaceuticals Inc. | Procédé de préparation d'agonistes du guanylate cyclase c |
| WO2013106547A1 (fr) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation |
| JP6499591B2 (ja) | 2013-02-25 | 2019-04-10 | シナジー ファーマシューティカルズ インコーポレイテッド | 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| WO2014151206A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
| CN105979959B (zh) | 2013-08-09 | 2021-11-30 | 阿德利克斯公司 | 用于抑制磷酸盐转运的化合物和方法 |
| WO2020237096A1 (fr) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combinaison pour baisser le phosphate sérique chez un patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1293565A (en) * | 1969-05-03 | 1972-10-18 | Aspro Nicholas Ltd | Aminophthalazines and pharmaceutical compositions thereof |
-
1978
- 1978-10-24 CA CA314,085A patent/CA1114379A/fr not_active Expired
- 1978-10-30 PH PH21752A patent/PH14659A/en unknown
- 1978-10-31 LU LU80458A patent/LU80458A1/fr unknown
- 1978-11-01 YU YU02536/78A patent/YU253678A/xx unknown
- 1978-11-01 NL NL7810864A patent/NL7810864A/xx not_active Application Discontinuation
- 1978-11-01 DK DK487978A patent/DK487978A/da unknown
- 1978-11-01 SE SE7811322A patent/SE7811322L/xx unknown
- 1978-11-01 FI FI783326A patent/FI783326A/fi unknown
- 1978-11-01 IL IL55844A patent/IL55844A/xx unknown
- 1978-11-02 AT AT0783978A patent/AT365184B/de not_active IP Right Cessation
- 1978-11-02 AU AU41276/78A patent/AU507007B2/en not_active Expired
- 1978-11-02 ES ES474764A patent/ES474764A0/es active Pending
- 1978-11-02 PT PT68734A patent/PT68734A/pt unknown
- 1978-11-02 IT IT29369/78A patent/IT1101279B/it active
- 1978-11-02 FR FR7831063A patent/FR2407927A1/fr active Granted
- 1978-11-02 DE DE19782847621 patent/DE2847621A1/de not_active Ceased
- 1978-11-02 JP JP13569778A patent/JPS5498783A/ja active Granted
- 1978-11-02 IE IE2166/78A patent/IE47481B1/en unknown
- 1978-11-03 BE BE191543A patent/BE871770A/fr unknown
- 1978-11-10 AR AR274311A patent/AR219561A1/es active
-
1979
- 1979-04-26 ES ES479993A patent/ES479993A1/es not_active Expired
- 1979-04-26 ES ES479994A patent/ES479994A1/es not_active Expired
- 1979-04-26 ES ES479991A patent/ES479991A1/es not_active Expired
- 1979-04-26 ES ES479992A patent/ES479992A1/es not_active Expired
- 1979-11-02 AR AR278750A patent/AR217578A1/es active
- 1979-11-02 AR AR278749A patent/AR217577A1/es active
-
1982
- 1982-03-23 YU YU02115/82A patent/YU211582A/xx unknown
- 1982-09-23 YU YU02116/82A patent/YU211682A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| YU211682A (en) | 1983-02-28 |
| IL55844A0 (en) | 1979-01-31 |
| AU4127678A (en) | 1979-05-17 |
| AR217578A1 (es) | 1980-03-31 |
| LU80458A1 (fr) | 1980-05-07 |
| FI783326A (fi) | 1979-05-04 |
| ES479993A1 (es) | 1980-08-16 |
| ATA783978A (de) | 1981-05-15 |
| ES474764A0 (es) | 1980-08-16 |
| JPS5498783A (en) | 1979-08-03 |
| ES479991A1 (es) | 1980-08-16 |
| PT68734A (en) | 1978-12-01 |
| IE47481B1 (en) | 1984-04-04 |
| SE7811322L (sv) | 1979-05-04 |
| JPS5538352B2 (fr) | 1980-10-03 |
| AU507007B2 (en) | 1980-01-31 |
| CA1114379A (fr) | 1981-12-15 |
| BE871770A (fr) | 1979-05-03 |
| IT1101279B (it) | 1985-09-28 |
| AT365184B (de) | 1981-12-28 |
| YU211582A (en) | 1983-02-28 |
| FR2407927A1 (fr) | 1979-06-01 |
| AR217577A1 (es) | 1980-03-31 |
| DE2847621A1 (de) | 1979-05-17 |
| FR2407927B1 (fr) | 1982-07-16 |
| YU253678A (en) | 1983-02-28 |
| NL7810864A (nl) | 1979-05-07 |
| PH14659A (en) | 1981-10-20 |
| IE782166L (en) | 1979-05-03 |
| IT7829369A0 (it) | 1978-11-02 |
| AR219561A1 (es) | 1980-08-29 |
| ES479994A1 (es) | 1980-08-16 |
| ES479992A1 (es) | 1980-09-01 |
| DK487978A (da) | 1979-05-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL54842A (en) | 1-piperidino-phthalazine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL55183A0 (en) | Novel imidazoquinazoline derivatives, their preparation and pharmaceutical compositions containing them | |
| IL51816A (en) | Steroids,their preparation and pharmaceutical compositions containing them | |
| IL55643A (en) | Cyclopeptides,their preparation and pharmaceutical compositions containing them | |
| IL55845A (en) | Quinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
| IL55844A (en) | 1-piperidino phthalazines,their preparation and pharmaceutical compositions containing them | |
| IL52867A (en) | Phenethylaminoalkyl isoquinolinones and benzazepinones,their preparation and pharmaceutical compositions containing same | |
| IL54337A (en) | 1-aminoindanes, their preparation and pharmaceutical compositions comprising them | |
| IL55765A (en) | Dehydropyridine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL56248A (en) | 4-spectinomycylamine and salts thereof,their preparation and pharmaceutical compositions containing them | |
| IL54535A0 (en) | Novel -lactam derivatives, their preparation and pharmaceutical compositions containing them | |
| IL53857A0 (en) | New aminoalkoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them | |
| MY8000099A (en) | Isobutyramides, their preparation and therapeutic compositions containing them | |
| IL55857A (en) | Benzodioxanylcarbonyl-piperazinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them | |
| IL53766A0 (en) | 4-diphenylmethylene-1-hydroxybenzyl-piperidine derivatives, their preparation and pharmaceutical compositions containing them | |
| IL55018A (en) | Benzylpyrimidines,their manufacture and pharmaceutical compositions containing them | |
| IL53861A0 (en) | Novel n-aralkylaniline derivatives, their preparation and pharmaceutical compositions containing them | |
| IL54326A0 (en) | Novel quinazoline derivatives, their preparation and pharmaceutical compositions containing them | |
| IL54899A (en) | Pyridazinylhydrazones,their preparation and pharmaceutical compositions containing them | |
| IL55120A0 (en) | New 3-pyridazine derivatives,their preparation and pharmaceutical compositions containing them | |
| IL55095A0 (en) | Novel piperidino-propanol derivatives,their preparation and pharmaceutical compositions containing them | |
| IL54169A (en) | Steroid spirooxazolidines,their preparation and pharmaceutical compositions containing them | |
| IL53948A0 (en) | New thiazinoindole derivatives, their preparation and pharmaceutical compositions containing them | |
| IL55352A0 (en) | New 3-amino-17a-aza-d-homoandrostane derivatives, their preparation and pharmaceutical compositions containing them | |
| IL56021A (en) | 2-heterocyclylalklyl-6-methoxy-naphathalenes,their preparation and pharmaceutical compositions containing them |