IL55460A - 2-guanidinomethyl-indolines,processes for their preparation and pharmalceutical compositions comprising them - Google Patents

2-guanidinomethyl-indolines,processes for their preparation and pharmalceutical compositions comprising them

Info

Publication number
IL55460A
IL55460A IL55460A IL5546078A IL55460A IL 55460 A IL55460 A IL 55460A IL 55460 A IL55460 A IL 55460A IL 5546078 A IL5546078 A IL 5546078A IL 55460 A IL55460 A IL 55460A
Authority
IL
Israel
Prior art keywords
pharmalceutical
guanidinomethyl
indolines
compositions
processes
Prior art date
Application number
IL55460A
Other languages
English (en)
Other versions
IL55460A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL55460A0 publication Critical patent/IL55460A0/xx
Publication of IL55460A publication Critical patent/IL55460A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL55460A 1977-09-03 1978-08-30 2-guanidinomethyl-indolines,processes for their preparation and pharmalceutical compositions comprising them IL55460A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772739723 DE2739723A1 (de) 1977-09-03 1977-09-03 2-guanidinomethyl-indoline und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL55460A0 IL55460A0 (en) 1978-10-31
IL55460A true IL55460A (en) 1981-03-31

Family

ID=6018021

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55460A IL55460A (en) 1977-09-03 1978-08-30 2-guanidinomethyl-indolines,processes for their preparation and pharmalceutical compositions comprising them

Country Status (10)

Country Link
US (1) US4260628A (it)
EP (1) EP0001546A1 (it)
JP (1) JPS5446778A (it)
AU (1) AU3939978A (it)
DD (1) DD138547A5 (it)
DE (1) DE2739723A1 (it)
ES (2) ES473038A1 (it)
IL (1) IL55460A (it)
IT (1) IT1106131B (it)
ZA (1) ZA785005B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963689A (en) * 1989-05-19 1990-10-16 Pfizer Inc. Heterocyclicguanidines as 5HT3 antagonists
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
CN105308021B (zh) 2013-06-17 2018-05-04 3M创新有限公司 用于制备胍基官能化单体的方法
CN113968855A (zh) * 2020-07-24 2022-01-25 中国科学院上海药物研究所 一种治疗血栓性疾病的化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3093632A (en) * 1961-02-02 1963-06-11 Ciba Geigy Corp Dibenzpolymethylenimino-alkylene-guanidines
US3317560A (en) * 1963-01-03 1967-05-02 Philips Corp Indol-3-yl alkylguanidine derivatives
US3354174A (en) * 1964-02-19 1967-11-21 Sterling Drug Inc 1-and 2-benzimidazolyl-lower-alkylamidoximes, amidines-, and guanidines
US3428653A (en) * 1965-06-28 1969-02-18 Sterling Drug Inc 3-indolylmethylguanidine
BE792724A (fr) * 1971-12-16 1973-06-14 Merck Patent Gmbh Derives de pyrazinoindole et leur procede de preparation
YU48175A (en) * 1975-02-27 1982-08-31 Egyt Gyogyszervegyeszeti Gyar Process for obtaining 2-guanidino-methyl-perhydroazocinn-sulfate

Also Published As

Publication number Publication date
US4260628A (en) 1981-04-07
IT7850946A0 (it) 1978-09-01
AU3939978A (en) 1980-03-06
DD138547A5 (de) 1979-11-07
JPS5446778A (en) 1979-04-12
ZA785005B (en) 1979-08-29
IT1106131B (it) 1985-11-11
EP0001546A1 (de) 1979-05-02
ES473038A1 (es) 1979-10-16
DE2739723A1 (de) 1979-03-08
IL55460A0 (en) 1978-10-31
ES480765A1 (es) 1979-11-16

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