IT1106131B - 2-guanidinometil-indolina e processo per la sua preparazione - Google Patents

2-guanidinometil-indolina e processo per la sua preparazione

Info

Publication number
IT1106131B
IT1106131B IT50946/78A IT5094678A IT1106131B IT 1106131 B IT1106131 B IT 1106131B IT 50946/78 A IT50946/78 A IT 50946/78A IT 5094678 A IT5094678 A IT 5094678A IT 1106131 B IT1106131 B IT 1106131B
Authority
IT
Italy
Prior art keywords
guanidinomethy
indoline
preparation
Prior art date
Application number
IT50946/78A
Other languages
English (en)
Other versions
IT7850946A0 (it
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IT7850946A0 publication Critical patent/IT7850946A0/it
Application granted granted Critical
Publication of IT1106131B publication Critical patent/IT1106131B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT50946/78A 1977-09-03 1978-09-01 2-guanidinometil-indolina e processo per la sua preparazione IT1106131B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772739723 DE2739723A1 (de) 1977-09-03 1977-09-03 2-guanidinomethyl-indoline und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IT7850946A0 IT7850946A0 (it) 1978-09-01
IT1106131B true IT1106131B (it) 1985-11-11

Family

ID=6018021

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50946/78A IT1106131B (it) 1977-09-03 1978-09-01 2-guanidinometil-indolina e processo per la sua preparazione

Country Status (10)

Country Link
US (1) US4260628A (it)
EP (1) EP0001546A1 (it)
JP (1) JPS5446778A (it)
AU (1) AU3939978A (it)
DD (1) DD138547A5 (it)
DE (1) DE2739723A1 (it)
ES (2) ES473038A1 (it)
IL (1) IL55460A (it)
IT (1) IT1106131B (it)
ZA (1) ZA785005B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963689A (en) * 1989-05-19 1990-10-16 Pfizer Inc. Heterocyclicguanidines as 5HT3 antagonists
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
EP3461811A1 (en) 2013-06-17 2019-04-03 3M Innovative Properties Co. Process for preparing guanidino-functional monomers
CN113968855A (zh) * 2020-07-24 2022-01-25 中国科学院上海药物研究所 一种治疗血栓性疾病的化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3093632A (en) * 1961-02-02 1963-06-11 Ciba Geigy Corp Dibenzpolymethylenimino-alkylene-guanidines
US3317560A (en) * 1963-01-03 1967-05-02 Philips Corp Indol-3-yl alkylguanidine derivatives
US3354174A (en) * 1964-02-19 1967-11-21 Sterling Drug Inc 1-and 2-benzimidazolyl-lower-alkylamidoximes, amidines-, and guanidines
US3428653A (en) * 1965-06-28 1969-02-18 Sterling Drug Inc 3-indolylmethylguanidine
BE792724A (fr) * 1971-12-16 1973-06-14 Merck Patent Gmbh Derives de pyrazinoindole et leur procede de preparation
HU170404B (it) * 1975-02-27 1977-06-28

Also Published As

Publication number Publication date
ZA785005B (en) 1979-08-29
IL55460A0 (en) 1978-10-31
EP0001546A1 (de) 1979-05-02
IT7850946A0 (it) 1978-09-01
IL55460A (en) 1981-03-31
AU3939978A (en) 1980-03-06
JPS5446778A (en) 1979-04-12
DE2739723A1 (de) 1979-03-08
US4260628A (en) 1981-04-07
DD138547A5 (de) 1979-11-07
ES473038A1 (es) 1979-10-16
ES480765A1 (es) 1979-11-16

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