ZA785005B - 2-guanidinomethyl-indolines and processes for their preparation - Google Patents
2-guanidinomethyl-indolines and processes for their preparationInfo
- Publication number
- ZA785005B ZA785005B ZA00785005A ZA785005A ZA785005B ZA 785005 B ZA785005 B ZA 785005B ZA 00785005 A ZA00785005 A ZA 00785005A ZA 785005 A ZA785005 A ZA 785005A ZA 785005 B ZA785005 B ZA 785005B
- Authority
- ZA
- South Africa
- Prior art keywords
- guanidinomethyl
- indolines
- processes
- preparation
- Prior art date
Links
- NBFCINMEQNKNCF-UHFFFAOYSA-N 2-(2,3-dihydro-1h-indol-2-ylmethyl)guanidine Chemical class C1=CC=C2NC(CNC(=N)N)CC2=C1 NBFCINMEQNKNCF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772739723 DE2739723A1 (de) | 1977-09-03 | 1977-09-03 | 2-guanidinomethyl-indoline und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA785005B true ZA785005B (en) | 1979-08-29 |
Family
ID=6018021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00785005A ZA785005B (en) | 1977-09-03 | 1978-09-01 | 2-guanidinomethyl-indolines and processes for their preparation |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4260628A (xx) |
| EP (1) | EP0001546A1 (xx) |
| JP (1) | JPS5446778A (xx) |
| AU (1) | AU3939978A (xx) |
| DD (1) | DD138547A5 (xx) |
| DE (1) | DE2739723A1 (xx) |
| ES (2) | ES473038A1 (xx) |
| IL (1) | IL55460A (xx) |
| IT (1) | IT1106131B (xx) |
| ZA (1) | ZA785005B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4963689A (en) * | 1989-05-19 | 1990-10-16 | Pfizer Inc. | Heterocyclicguanidines as 5HT3 antagonists |
| FR2822463B1 (fr) | 2001-03-21 | 2004-07-30 | Lipha | Derives bicycliques de guanidines et leurs applications en therapeutique |
| CN105308021B (zh) | 2013-06-17 | 2018-05-04 | 3M创新有限公司 | 用于制备胍基官能化单体的方法 |
| CN113968855A (zh) * | 2020-07-24 | 2022-01-25 | 中国科学院上海药物研究所 | 一种治疗血栓性疾病的化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3093632A (en) * | 1961-02-02 | 1963-06-11 | Ciba Geigy Corp | Dibenzpolymethylenimino-alkylene-guanidines |
| US3317560A (en) * | 1963-01-03 | 1967-05-02 | Philips Corp | Indol-3-yl alkylguanidine derivatives |
| US3354174A (en) * | 1964-02-19 | 1967-11-21 | Sterling Drug Inc | 1-and 2-benzimidazolyl-lower-alkylamidoximes, amidines-, and guanidines |
| US3428653A (en) * | 1965-06-28 | 1969-02-18 | Sterling Drug Inc | 3-indolylmethylguanidine |
| BE792724A (fr) * | 1971-12-16 | 1973-06-14 | Merck Patent Gmbh | Derives de pyrazinoindole et leur procede de preparation |
| YU48175A (en) * | 1975-02-27 | 1982-08-31 | Egyt Gyogyszervegyeszeti Gyar | Process for obtaining 2-guanidino-methyl-perhydroazocinn-sulfate |
-
1977
- 1977-09-03 DE DE19772739723 patent/DE2739723A1/de not_active Withdrawn
-
1978
- 1978-08-07 EP EP78100615A patent/EP0001546A1/de not_active Withdrawn
- 1978-08-30 AU AU39399/78A patent/AU3939978A/en active Pending
- 1978-08-30 IL IL55460A patent/IL55460A/xx unknown
- 1978-09-01 JP JP10635078A patent/JPS5446778A/ja active Pending
- 1978-09-01 ZA ZA00785005A patent/ZA785005B/xx unknown
- 1978-09-01 ES ES473038A patent/ES473038A1/es not_active Expired
- 1978-09-01 IT IT50946/78A patent/IT1106131B/it active
- 1978-09-01 DD DD78207604A patent/DD138547A5/xx unknown
-
1979
- 1979-05-21 ES ES480765A patent/ES480765A1/es not_active Expired
- 1979-09-26 US US06/078,855 patent/US4260628A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US4260628A (en) | 1981-04-07 |
| IT7850946A0 (it) | 1978-09-01 |
| AU3939978A (en) | 1980-03-06 |
| DD138547A5 (de) | 1979-11-07 |
| JPS5446778A (en) | 1979-04-12 |
| IL55460A (en) | 1981-03-31 |
| IT1106131B (it) | 1985-11-11 |
| EP0001546A1 (de) | 1979-05-02 |
| ES473038A1 (es) | 1979-10-16 |
| DE2739723A1 (de) | 1979-03-08 |
| IL55460A0 (en) | 1978-10-31 |
| ES480765A1 (es) | 1979-11-16 |
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