IL54252A - Diisopropylaminoalkyl- -(substituted aminoalkyl)-phenyl-acetamide derivatives,their preparation and pharmaceutical and veterinary compostions containing them - Google Patents

Diisopropylaminoalkyl- -(substituted aminoalkyl)-phenyl-acetamide derivatives,their preparation and pharmaceutical and veterinary compostions containing them

Info

Publication number
IL54252A
IL54252A IL54252A IL5425278A IL54252A IL 54252 A IL54252 A IL 54252A IL 54252 A IL54252 A IL 54252A IL 5425278 A IL5425278 A IL 5425278A IL 54252 A IL54252 A IL 54252A
Authority
IL
Israel
Prior art keywords
diisopropylaminoalkyl
veterinary
phenyl
pharmaceutical
preparation
Prior art date
Application number
IL54252A
Other languages
English (en)
Other versions
IL54252A0 (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL54252A0 publication Critical patent/IL54252A0/xx
Publication of IL54252A publication Critical patent/IL54252A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL54252A 1977-03-11 1978-03-10 Diisopropylaminoalkyl- -(substituted aminoalkyl)-phenyl-acetamide derivatives,their preparation and pharmaceutical and veterinary compostions containing them IL54252A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,563 US4107205A (en) 1977-03-11 1977-03-11 α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds

Publications (2)

Publication Number Publication Date
IL54252A0 IL54252A0 (en) 1978-06-15
IL54252A true IL54252A (en) 1981-09-13

Family

ID=25107748

Family Applications (1)

Application Number Title Priority Date Filing Date
IL54252A IL54252A (en) 1977-03-11 1978-03-10 Diisopropylaminoalkyl- -(substituted aminoalkyl)-phenyl-acetamide derivatives,their preparation and pharmaceutical and veterinary compostions containing them

Country Status (22)

Country Link
US (2) US4107205A (de)
JP (1) JPS53121737A (de)
AT (1) AT355557B (de)
AU (1) AU520656B2 (de)
BE (1) BE864822A (de)
CA (1) CA1102339A (de)
CH (1) CH635312A5 (de)
DE (1) DE2810143A1 (de)
DK (1) DK107878A (de)
ES (1) ES467702A1 (de)
FI (1) FI780771A (de)
FR (1) FR2383163A1 (de)
GB (1) GB1580588A (de)
GR (1) GR74125B (de)
IE (1) IE46482B1 (de)
IL (1) IL54252A (de)
NL (1) NL7802672A (de)
NO (1) NO148186C (de)
NZ (1) NZ186653A (de)
PT (1) PT67765A (de)
SE (1) SE7802751L (de)
ZA (1) ZA781429B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217306A (en) * 1978-05-01 1980-08-12 G. D. Searle & Co. α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]-acetamides
US4560754A (en) * 1983-09-14 1985-12-24 G. D. Searle & Co. Substituted 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]decan-4-ones and 5-phenyl-5-(aminoalkyl)-1,3-diazabicyclo[4.4.0]dec-2-en-4-ones
US4639524A (en) * 1984-07-09 1987-01-27 G. D. Searle & Co. Monobasic disobutamide derivatives
US5097035A (en) * 1984-07-09 1992-03-17 G. D. Searle & Co. Monobasic disobutamide derivatives
US4812451A (en) * 1984-10-19 1989-03-14 A. H. Robins Company, Incorporated 1-(aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-α,.alpha.
US4810703A (en) * 1984-10-19 1989-03-07 A. H. Robins Company, Incorporated 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles
US4847301A (en) * 1985-11-13 1989-07-11 Pennwalt Corporation Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
US5432284A (en) * 1993-09-08 1995-07-11 G. D. Searle & Co. Process for the preparation of heterocyclic alkylamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2884436A (en) * 1954-08-28 1959-04-28 Nl Combinatie Chem Ind Parasympathicolytically active alpha, alpha-diphenyl-gamma-dialkylaminobutyramide compounds and manufacture thereof
US3022314A (en) * 1955-06-20 1962-02-20 Upjohn Co Alpha-phenyl-omega-amino-alkanamides
GB796839A (en) * 1955-06-23 1958-06-18 Pharmacia Ab N,n-disubstituted amides of aryl acetic acids
US3078275A (en) * 1956-05-28 1963-02-19 Upjohn Co N, n-disubstituted-alpha-(tertiaryaminoalkyl)-alpha, alpha-diphenylacetamides
US2894955A (en) * 1956-11-19 1959-07-14 Upjohn Co Organic compounds
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
US3225091A (en) * 1962-02-01 1965-12-21 Lilly Co Eli Anticholinergic substituted butyramides
NL124729C (de) * 1963-05-14

Also Published As

Publication number Publication date
US4153797A (en) 1979-05-08
NO148186B (no) 1983-05-16
JPS53121737A (en) 1978-10-24
ZA781429B (en) 1979-04-25
GR74125B (de) 1984-06-06
CH635312A5 (de) 1983-03-31
AU3402578A (en) 1979-09-13
IE46482B1 (en) 1983-06-29
AT355557B (de) 1980-03-10
BE864822A (fr) 1978-09-13
NO780869L (no) 1978-09-12
FI780771A (fi) 1978-09-12
SE7802751L (sv) 1978-09-12
GB1580588A (en) 1980-12-03
IE780501L (en) 1978-09-11
NZ186653A (en) 1979-11-01
DE2810143A1 (de) 1978-09-14
PT67765A (en) 1978-04-01
DK107878A (da) 1978-09-12
FR2383163A1 (fr) 1978-10-06
IL54252A0 (en) 1978-06-15
ATA173578A (de) 1979-08-15
NL7802672A (nl) 1978-09-13
ES467702A1 (es) 1978-10-16
CA1102339A (en) 1981-06-02
NO148186C (no) 1983-08-24
US4107205A (en) 1978-08-15
FR2383163B1 (de) 1981-07-31
AU520656B2 (en) 1982-02-18

Similar Documents

Publication Publication Date Title
IL56155A (en) Substituted alkanoylanilide derivatives,their preparation and pharmaceutical compositions comprising them
DE2860900D1 (en) Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
IL54842A (en) 1-piperidino-phthalazine derivatives,their preparation and pharmaceutical compositions containing them
IL55557A0 (en) New imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL56115A (en) 14-deoxy-14-glycoside-mutilin derivatives,process for their preparation and pharmaceutical and veterinary compositions containing them
IL53996A (en) 1-substituted-2-fluoroalkylthio-4,5-diphenyl-imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL51342A (en) Ethoxyquin derivatives,their preparation and pharmaceutical and veterinary compositions comprising them
IL56017A (en) 5-cyano-prostacyclin derivatives,their manufacture and pharmaceutical compositions containing them
IL56284A (en) 7-(2-thiazolyl-2-alkoxyiminoacetamido)-cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL55765A (en) Dehydropyridine derivatives,their preparation and pharmaceutical compositions containing them
DE2861361D1 (en) 1-n-acylated-4-o-glycosyl-6-o-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them
IL54535A0 (en) Novel -lactam derivatives, their preparation and pharmaceutical compositions containing them
IL53857A0 (en) New aminoalkoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
IL55813A0 (en) Movel triazile derivatives, their preparation and pharmaceutical compositions containing them
IL54252A (en) Diisopropylaminoalkyl- -(substituted aminoalkyl)-phenyl-acetamide derivatives,their preparation and pharmaceutical and veterinary compostions containing them
DE2860410D1 (en) 2-piperazinotetraline derivatives, their preparation and their use as medicines
IL53926A0 (en) New oxadiazolopyrimidine derivatives, their manufacture and pharmaceutical compositions containing them
IL55894A (en) 1-alkylenedithia (or oxathia) benzyl-4-heteroaryl-piperazine derivatives,their preparation and pharmaceutical compositions containing them
IL54949A0 (en) New quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL55858A (en) Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL55857A (en) Benzodioxanylcarbonyl-piperazinoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL53766A0 (en) 4-diphenylmethylene-1-hydroxybenzyl-piperidine derivatives, their preparation and pharmaceutical compositions containing them
DE2861767D1 (en) Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them
IL53995A (en) Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL54819A (en) Imidazole derivatives,their preparation and pharmaceutical compositions containing them