IL51509A - Bis-trimethylsilyl cefamandole and process for purifying crude cefamandole - Google Patents

Bis-trimethylsilyl cefamandole and process for purifying crude cefamandole

Info

Publication number
IL51509A
IL51509A IL51509A IL5150977A IL51509A IL 51509 A IL51509 A IL 51509A IL 51509 A IL51509 A IL 51509A IL 5150977 A IL5150977 A IL 5150977A IL 51509 A IL51509 A IL 51509A
Authority
IL
Israel
Prior art keywords
cefamandole
trimethylsilyl
bis
purifying crude
purifying
Prior art date
Application number
IL51509A
Other languages
English (en)
Other versions
IL51509A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL51509A0 publication Critical patent/IL51509A0/xx
Publication of IL51509A publication Critical patent/IL51509A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
IL51509A 1976-03-17 1977-02-21 Bis-trimethylsilyl cefamandole and process for purifying crude cefamandole IL51509A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/667,753 US4035361A (en) 1976-03-17 1976-03-17 Bis-trimethylsilyl cefamandole and process therefor

Publications (2)

Publication Number Publication Date
IL51509A0 IL51509A0 (en) 1977-04-29
IL51509A true IL51509A (en) 1979-11-30

Family

ID=24679489

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51509A IL51509A (en) 1976-03-17 1977-02-21 Bis-trimethylsilyl cefamandole and process for purifying crude cefamandole

Country Status (12)

Country Link
US (1) US4035361A (de)
JP (1) JPS5934199B2 (de)
BE (1) BE852487A (de)
CA (1) CA1077926A (de)
CH (2) CH627472A5 (de)
DE (1) DE2711095C2 (de)
ES (2) ES456689A1 (de)
FR (1) FR2344563A1 (de)
GB (1) GB1544178A (de)
IE (1) IE44605B1 (de)
IL (1) IL51509A (de)
NL (1) NL7702634A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148817A (en) * 1976-03-25 1979-04-10 Eli Lilly And Company Process and intermediates for preparing cephalosporin antibiotics
US4223134A (en) * 1978-11-28 1980-09-16 Eli Lilly And Company Process for preparing cephalosporin antibiotics
GB9503717D0 (en) * 1995-02-24 1995-04-12 Smithkline Beecham Plc Novel compounds
CN104530086B (zh) * 2014-12-16 2015-12-09 天津大学 头孢孟多酯钠化合物的新晶型及其结晶制备方法
US9834567B1 (en) * 2014-12-16 2017-12-05 Tianjin University Crystalline form of cefamandole nafate compound, preparation and preparing method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
US3840531A (en) * 1972-03-21 1974-10-08 Lilly Co Eli Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof

Also Published As

Publication number Publication date
IL51509A0 (en) 1977-04-29
JPS5934199B2 (ja) 1984-08-21
DE2711095C2 (de) 1982-03-11
IE44605L (en) 1977-09-17
GB1544178A (en) 1979-04-11
ES456689A1 (es) 1978-01-16
DE2711095A1 (de) 1977-09-22
FR2344563A1 (fr) 1977-10-14
BE852487A (fr) 1977-09-15
FR2344563B1 (de) 1980-03-28
JPS52113993A (en) 1977-09-24
CH627472A5 (de) 1982-01-15
CA1077926A (en) 1980-05-20
NL7702634A (nl) 1977-09-20
US4035361A (en) 1977-07-12
IE44605B1 (en) 1982-01-27
CH630640A5 (de) 1982-06-30
ES456823A1 (es) 1978-02-16

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