IL51085A - 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them - Google Patents
2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing themInfo
- Publication number
- IL51085A IL51085A IL51085A IL5108576A IL51085A IL 51085 A IL51085 A IL 51085A IL 51085 A IL51085 A IL 51085A IL 5108576 A IL5108576 A IL 5108576A IL 51085 A IL51085 A IL 51085A
- Authority
- IL
- Israel
- Prior art keywords
- pharmalceutical
- pregna
- trihydroxy
- dichloro
- diene
- Prior art date
Links
- VZNSGKWZDKMWNV-LKELCSFTSA-N (8s,9r,10s,13s,14s,17r)-2,9-dichloro-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one Chemical class C1C(F)C2=CC(=O)C(Cl)=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1CC(C)[C@@](C(=O)CO)(O)[C@@]1(C)CC2O VZNSGKWZDKMWNV-LKELCSFTSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1615075A CH626632A5 (en) | 1975-12-12 | 1975-12-12 | Process for the preparation of halopregnadienes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL51085A0 IL51085A0 (en) | 1977-02-28 |
| IL51085A true IL51085A (en) | 1980-09-16 |
Family
ID=4414834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL51085A IL51085A (en) | 1975-12-12 | 1976-12-10 | 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them |
Country Status (19)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT78973A (en) * | 1984-07-25 | 1984-08-01 | Joao Emerico Villax | New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid |
-
1975
- 1975-12-12 CH CH1615075A patent/CH626632A5/de not_active IP Right Cessation
-
1976
- 1976-12-09 FR FR7637093A patent/FR2358152A1/fr active Granted
- 1976-12-09 NL NL7613711A patent/NL7613711A/xx not_active Application Discontinuation
- 1976-12-09 DE DE19762655802 patent/DE2655802A1/de not_active Withdrawn
- 1976-12-10 DK DK557576AA patent/DK142326B/da unknown
- 1976-12-10 DD DD7600196260A patent/DD128682A5/xx unknown
- 1976-12-10 GB GB51695/76A patent/GB1563595A/en not_active Expired
- 1976-12-10 NZ NZ182865A patent/NZ182865A/xx unknown
- 1976-12-10 SE SE7613919A patent/SE7613919L/xx unknown
- 1976-12-10 AU AU20471/76A patent/AU510864B2/en not_active Expired
- 1976-12-10 HU HU76CI1703A patent/HU176936B/hu unknown
- 1976-12-10 ES ES454119A patent/ES454119A1/es not_active Expired
- 1976-12-10 BE BE173137A patent/BE849267A/xx unknown
- 1976-12-10 CA CA267,597A patent/CA1078824A/en not_active Expired
- 1976-12-10 ZA ZA767381A patent/ZA767381B/xx unknown
- 1976-12-10 IL IL51085A patent/IL51085A/xx unknown
- 1976-12-10 AT AT914176A patent/AT353432B/de not_active IP Right Cessation
- 1976-12-10 IE IE2699/76A patent/IE44512B1/en unknown
- 1976-12-11 JP JP51149325A patent/JPS5273852A/ja active Pending
-
1977
- 1977-12-29 ES ES465551A patent/ES465551A1/es not_active Expired
-
1980
- 1980-10-27 CH CH799480A patent/CH626094A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE849267A (fr) | 1977-06-10 |
| IL51085A0 (en) | 1977-02-28 |
| CA1078824A (en) | 1980-06-03 |
| AT353432B (de) | 1979-11-12 |
| FR2358152B1 (enrdf_load_html_response) | 1982-10-22 |
| ZA767381B (en) | 1977-11-30 |
| FR2358152A1 (fr) | 1978-02-10 |
| DK142326B (da) | 1980-10-13 |
| DK557576A (enrdf_load_html_response) | 1977-06-13 |
| ES454119A1 (es) | 1978-03-01 |
| NZ182865A (en) | 1979-06-08 |
| CH626094A5 (en) | 1981-10-30 |
| JPS5273852A (en) | 1977-06-21 |
| CH626632A5 (en) | 1981-11-30 |
| IE44512B1 (en) | 1981-12-30 |
| DE2655802A1 (de) | 1977-06-16 |
| DK142326C (enrdf_load_html_response) | 1981-03-09 |
| ES465551A1 (es) | 1978-09-16 |
| HU176936B (hu) | 1981-06-28 |
| AU2047176A (en) | 1978-06-15 |
| GB1563595A (en) | 1980-03-26 |
| DD128682A5 (de) | 1977-12-07 |
| NL7613711A (nl) | 1977-06-14 |
| ATA914176A (de) | 1979-04-15 |
| IE44512L (en) | 1977-06-12 |
| SE7613919L (sv) | 1977-06-13 |
| AU510864B2 (en) | 1980-07-17 |
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