IL50099A - Quaternary salts of 2 ,16 -di(cyclic amino)-3 ,17 -di(lower alkanoyloxy)-5 -androstanes and process for their preparation - Google Patents

Quaternary salts of 2 ,16 -di(cyclic amino)-3 ,17 -di(lower alkanoyloxy)-5 -androstanes and process for their preparation

Info

Publication number
IL50099A
IL50099A IL50099A IL5009976A IL50099A IL 50099 A IL50099 A IL 50099A IL 50099 A IL50099 A IL 50099A IL 5009976 A IL5009976 A IL 5009976A IL 50099 A IL50099 A IL 50099A
Authority
IL
Israel
Prior art keywords
androstanes
preparation
cyclic amino
lower alkanoyloxy
quaternary salts
Prior art date
Application number
IL50099A
Other languages
English (en)
Other versions
IL50099A0 (en
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL50099A0 publication Critical patent/IL50099A0/xx
Publication of IL50099A publication Critical patent/IL50099A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL50099A 1975-08-01 1976-07-22 Quaternary salts of 2 ,16 -di(cyclic amino)-3 ,17 -di(lower alkanoyloxy)-5 -androstanes and process for their preparation IL50099A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75RI00000575A HU172522B (hu) 1975-08-01 1975-08-01 Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej

Publications (2)

Publication Number Publication Date
IL50099A0 IL50099A0 (en) 1976-09-30
IL50099A true IL50099A (en) 1980-02-29

Family

ID=11000984

Family Applications (1)

Application Number Title Priority Date Filing Date
IL50099A IL50099A (en) 1975-08-01 1976-07-22 Quaternary salts of 2 ,16 -di(cyclic amino)-3 ,17 -di(lower alkanoyloxy)-5 -androstanes and process for their preparation

Country Status (19)

Country Link
US (1) US4101545A (nl)
AT (1) AT359218B (nl)
AU (1) AU499988B2 (nl)
BE (1) BE844643A (nl)
CA (1) CA1084044A (nl)
CS (1) CS189782B2 (nl)
DD (1) DD126820A5 (nl)
DE (1) DE2634336C3 (nl)
DK (1) DK138460B (nl)
FR (1) FR2319370A1 (nl)
GB (1) GB1540405A (nl)
HU (1) HU172522B (nl)
IL (1) IL50099A (nl)
NL (1) NL185079C (nl)
PL (1) PL101306B1 (nl)
RO (1) RO75980A (nl)
SE (1) SE409867B (nl)
SU (1) SU1001859A3 (nl)
YU (1) YU187776A (nl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2962627D1 (en) * 1978-09-05 1982-06-09 Akzo Nv Acid addition salts of 16-beta-monoquaternary ammonium derivatives of 2-beta, 16-beta-bis-piperidino-androstanes and pharmaceutical preparations containing same
DE7930964U1 (de) * 1978-11-03 1984-10-04 Papst-Motoren GmbH & Co KG, 7742 St Georgen Magnetplattenantrieb
IE50675B1 (en) * 1979-12-12 1986-06-11 Akzo Nv Bis-and mono-quaternary ammonium derivatives of 2beta,16beta-dipiperidino-5alpha-androstanes,processes for their preparation and pharmaceutical preparations
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
US5506354A (en) * 1985-09-12 1996-04-09 The Upjohn Company Imidazolylpiperazinyl steroids
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
HU168431B (nl) * 1972-07-27 1976-04-28

Also Published As

Publication number Publication date
US4101545A (en) 1978-07-18
DK138460B (da) 1978-09-11
SU1001859A3 (ru) 1983-02-28
ATA564176A (de) 1980-03-15
RO75980A (ro) 1981-08-17
DE2634336C3 (de) 1978-11-23
CA1084044A (en) 1980-08-19
HU172522B (hu) 1978-09-28
DD126820A5 (nl) 1977-08-17
CS189782B2 (en) 1979-04-30
AU499988B2 (en) 1979-05-10
BE844643A (fr) 1976-11-16
PL101306B1 (pl) 1978-12-30
DK340976A (nl) 1977-02-02
DE2634336A1 (de) 1977-02-03
AU1612576A (en) 1978-01-26
DK138460C (nl) 1979-02-12
FR2319370A1 (fr) 1977-02-25
NL185079B (nl) 1989-08-16
GB1540405A (en) 1979-02-14
SE7608608L (sv) 1977-02-02
FR2319370B1 (nl) 1980-07-25
AT359218B (de) 1980-10-27
IL50099A0 (en) 1976-09-30
SE409867B (sv) 1979-09-10
NL7608538A (nl) 1977-02-03
YU187776A (en) 1982-05-31
DE2634336B2 (de) 1978-03-23
NL185079C (nl) 1990-01-16

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