FR2319370A1 - Nouveaux derives de diaminoandrostane et leurs sels d'addition d'acides et sels quaternaires doues d'activite curarisante et leur procede de preparation - Google Patents

Nouveaux derives de diaminoandrostane et leurs sels d'addition d'acides et sels quaternaires doues d'activite curarisante et leur procede de preparation

Info

Publication number
FR2319370A1
FR2319370A1 FR7623042A FR7623042A FR2319370A1 FR 2319370 A1 FR2319370 A1 FR 2319370A1 FR 7623042 A FR7623042 A FR 7623042A FR 7623042 A FR7623042 A FR 7623042A FR 2319370 A1 FR2319370 A1 FR 2319370A1
Authority
FR
France
Prior art keywords
salts
diaminoandrostane
curarizing
acids
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7623042A
Other languages
English (en)
Other versions
FR2319370B1 (fr
Inventor
Zoltan Tuba
Maria Marsai
Katalin Biro
Laszlo Szporny
Egon Karpati
Szabolos Szeberenyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2319370A1 publication Critical patent/FR2319370A1/fr
Application granted granted Critical
Publication of FR2319370B1 publication Critical patent/FR2319370B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
FR7623042A 1975-08-01 1976-07-28 Nouveaux derives de diaminoandrostane et leurs sels d'addition d'acides et sels quaternaires doues d'activite curarisante et leur procede de preparation Granted FR2319370A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75RI00000575A HU172522B (hu) 1975-08-01 1975-08-01 Sposob poluchenija novykh proizvodnykh 2beta, 16beta-diamino-androstana i ikh chetvertichnykh solej

Publications (2)

Publication Number Publication Date
FR2319370A1 true FR2319370A1 (fr) 1977-02-25
FR2319370B1 FR2319370B1 (fr) 1980-07-25

Family

ID=11000984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7623042A Granted FR2319370A1 (fr) 1975-08-01 1976-07-28 Nouveaux derives de diaminoandrostane et leurs sels d'addition d'acides et sels quaternaires doues d'activite curarisante et leur procede de preparation

Country Status (19)

Country Link
US (1) US4101545A (fr)
AT (1) AT359218B (fr)
AU (1) AU499988B2 (fr)
BE (1) BE844643A (fr)
CA (1) CA1084044A (fr)
CS (1) CS189782B2 (fr)
DD (1) DD126820A5 (fr)
DE (1) DE2634336C3 (fr)
DK (1) DK138460B (fr)
FR (1) FR2319370A1 (fr)
GB (1) GB1540405A (fr)
HU (1) HU172522B (fr)
IL (1) IL50099A (fr)
NL (1) NL185079C (fr)
PL (1) PL101306B1 (fr)
RO (1) RO75980A (fr)
SE (1) SE409867B (fr)
SU (1) SU1001859A3 (fr)
YU (1) YU187776A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008824A1 (fr) * 1978-09-05 1980-03-19 Akzo N.V. Sels d'addition acides de 2-bêta, 16-bêta-bis pipéridino-androstane-16 bêta-monoammonium quaternaire et préparations pharmaceutiques les contenant
WO1981001710A1 (fr) * 1979-12-12 1981-06-25 Akzo Nv Mono et bis piperidinium androstanes

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2944212C3 (de) * 1978-11-03 1994-10-20 Papst Motoren Gmbh & Co Kg Magnetplattenantrieb
HU195972B (en) * 1985-07-01 1988-08-29 Richter Gedeon Vegyeszet Process for producing new diamino-androstane derivatives and pharmaceutical compositions containing them
US5380840A (en) * 1985-09-12 1995-01-10 The Upjohn Company Triazinylpiperazinyl steroids
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
USRE35053E (en) * 1985-09-12 1995-10-10 The Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
IT1277700B1 (it) * 1995-12-22 1997-11-11 Poli Ind Chimica Spa Processo di preparazione di 2-beta, 16-beta-diamino 3-alfa, 17-beta- diacilossi 5-alfaandrostani, bloccanti neuromuscolari a struttura

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1138605A (en) * 1965-02-19 1969-01-01 Organon Labor Ltd Improvements in or relating to new 2-ß,16-ß-diamino-androstanes
HU168431B (fr) * 1972-07-27 1976-04-28

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008824A1 (fr) * 1978-09-05 1980-03-19 Akzo N.V. Sels d'addition acides de 2-bêta, 16-bêta-bis pipéridino-androstane-16 bêta-monoammonium quaternaire et préparations pharmaceutiques les contenant
US4237126A (en) * 1978-09-05 1980-12-02 Akzona Incorporated 2β, 16β-bis-piperidino-androstanes
US4297351A (en) * 1978-09-05 1981-10-27 Akzona Incorporated Method of manufacture and use of improved 2β, 16β-piperidino androstanes
WO1981001710A1 (fr) * 1979-12-12 1981-06-25 Akzo Nv Mono et bis piperidinium androstanes
EP0032261B1 (fr) * 1979-12-12 1983-09-28 Akzo N.V. Dérivés bis- et mono-ammonium quaternaire de 2-bêta, 16-bêta-dipipéridino-5-alpha-androstanes, procédé pour leur préparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
YU187776A (en) 1982-05-31
DK340976A (fr) 1977-02-02
GB1540405A (en) 1979-02-14
HU172522B (hu) 1978-09-28
BE844643A (fr) 1976-11-16
NL7608538A (nl) 1977-02-03
US4101545A (en) 1978-07-18
DD126820A5 (fr) 1977-08-17
RO75980A (fr) 1981-08-17
AT359218B (de) 1980-10-27
DK138460C (fr) 1979-02-12
DE2634336B2 (de) 1978-03-23
NL185079B (nl) 1989-08-16
PL101306B1 (pl) 1978-12-30
IL50099A0 (en) 1976-09-30
AU1612576A (en) 1978-01-26
ATA564176A (de) 1980-03-15
SU1001859A3 (ru) 1983-02-28
FR2319370B1 (fr) 1980-07-25
SE409867B (sv) 1979-09-10
IL50099A (en) 1980-02-29
DE2634336C3 (de) 1978-11-23
CS189782B2 (en) 1979-04-30
NL185079C (nl) 1990-01-16
AU499988B2 (en) 1979-05-10
DE2634336A1 (de) 1977-02-03
SE7608608L (sv) 1977-02-02
DK138460B (da) 1978-09-11
CA1084044A (fr) 1980-08-19

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Legal Events

Date Code Title Description
ST Notification of lapse