IL48061A - 4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL48061A IL48061A IL48061A IL4806175A IL48061A IL 48061 A IL48061 A IL 48061A IL 48061 A IL48061 A IL 48061A IL 4806175 A IL4806175 A IL 4806175A IL 48061 A IL48061 A IL 48061A
- Authority
- IL
- Israel
- Prior art keywords
- cis
- phenyl
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50430274A | 1974-09-09 | 1974-09-09 | |
US59946175A | 1975-08-01 | 1975-08-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL48061A0 IL48061A0 (en) | 1975-11-25 |
IL48061A true IL48061A (en) | 1979-09-30 |
Family
ID=27054787
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL48061A IL48061A (en) | 1974-09-09 | 1975-09-05 | 4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (19)
Country | Link |
---|---|
US (1) | US4150135A (el) |
JP (1) | JPS5154572A (el) |
AR (1) | AR208562A1 (el) |
AU (1) | AU503631B2 (el) |
BE (1) | BE833212A (el) |
DD (1) | DD123190A5 (el) |
DE (1) | DE2539907A1 (el) |
DK (1) | DK401575A (el) |
ES (2) | ES440830A1 (el) |
FI (1) | FI752516A (el) |
FR (2) | FR2283681A1 (el) |
GB (1) | GB1484431A (el) |
IE (1) | IE41898B1 (el) |
IL (1) | IL48061A (el) |
LU (1) | LU73348A1 (el) |
NL (1) | NL7510617A (el) |
NO (1) | NO753062L (el) |
SE (1) | SE7509022L (el) |
SU (1) | SU682126A3 (el) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4419517A (en) * | 1973-06-01 | 1983-12-06 | E. I. Du Pont De Nemours & Co. | 4a-Aryl-trans-decahydroisoquinolines |
US4219652A (en) * | 1975-09-30 | 1980-08-26 | Eli Lilly And Company | N-Methyl and N-phenethyl-cis-decahydroisoquinolines |
US4301290A (en) * | 1975-12-16 | 1981-11-17 | Sandoz Ltd. | Organic compounds |
DE2636684C3 (de) * | 1976-08-14 | 1980-06-19 | Merck Patent Gmbh, 6100 Darmstadt | Phenylcyclohexanderivate und ihre Verwendung in flüssigkristallinen Dielektrika |
DE2702598C2 (de) * | 1977-01-22 | 1984-10-25 | Merck Patent Gmbh, 6100 Darmstadt | Cyclohexylcyclohexane und diese enthaltende Dielektrika |
US4118386A (en) * | 1977-04-04 | 1978-10-03 | Hoffmann-La Roche Inc. | Synthesis of imidazo[1,5-a]diazepine-3-carboxylates |
US4289882A (en) | 1978-04-26 | 1981-09-15 | The United States Of America As Represented By The Department Of Health & Human Services | 4A-Aryl-decahydroisoquinolines |
JPS57122041A (en) * | 1981-01-21 | 1982-07-29 | Suntory Ltd | Phenylclohexane derivative |
US4349677A (en) * | 1981-11-09 | 1982-09-14 | Morton-Norwich Products, Inc. | 3,4-Dihydro-3,4-isoquinolinedione 4-oxime |
US4537963A (en) * | 1981-12-28 | 1985-08-27 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-E]isoquinolines |
US4421916A (en) * | 1981-12-28 | 1983-12-20 | E. I. Du Pont De Nemours & Co. | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
US4579952A (en) * | 1981-12-28 | 1986-04-01 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
IT1307327B1 (it) * | 1995-09-12 | 2001-10-30 | Smithkline Beecham Spa | Derivati idroisochinolinici sostituiti |
ES2780699T3 (es) | 2013-07-10 | 2020-08-26 | Vertex Pharma | Amidas de piperidina fusionadas útiles como moduladores de canales iónicos |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2740788A (en) * | 1956-04-03 | J-hydroxy-n-propargyl-morphinanes | ||
DE1670694B2 (de) | 1966-05-05 | 1976-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von tetrahydroisochinolinen |
US3546227A (en) * | 1966-12-01 | 1970-12-08 | Sandoz Ag | 2,3-dihydro-1h-benz(d,e)isoquinoline carboxamidines |
US3666763A (en) * | 1970-01-06 | 1972-05-30 | Hoffmann La Roche | 4-phenyl isoquinolines and process for preparing same |
ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
-
1975
- 1975-08-12 SE SE7509022A patent/SE7509022L/xx unknown
- 1975-09-05 IL IL48061A patent/IL48061A/xx unknown
- 1975-09-08 DK DK401575A patent/DK401575A/da not_active Application Discontinuation
- 1975-09-08 DD DD188238A patent/DD123190A5/xx unknown
- 1975-09-08 SU SU752169463A patent/SU682126A3/ru active
- 1975-09-08 NO NO753062A patent/NO753062L/no unknown
- 1975-09-08 GB GB36885/75A patent/GB1484431A/en not_active Expired
- 1975-09-08 AU AU84608/75A patent/AU503631B2/en not_active Expired
- 1975-09-08 LU LU73348A patent/LU73348A1/xx unknown
- 1975-09-08 DE DE19752539907 patent/DE2539907A1/de not_active Withdrawn
- 1975-09-08 FI FI752516A patent/FI752516A/fi not_active Application Discontinuation
- 1975-09-09 FR FR7527562A patent/FR2283681A1/fr not_active Withdrawn
- 1975-09-09 NL NL7510617A patent/NL7510617A/xx not_active Application Discontinuation
- 1975-09-09 ES ES440830A patent/ES440830A1/es not_active Expired
- 1975-09-09 IE IE1959/75A patent/IE41898B1/en unknown
- 1975-09-09 BE BE159859A patent/BE833212A/xx unknown
- 1975-09-09 AR AR260314A patent/AR208562A1/es active
- 1975-09-09 JP JP50109420A patent/JPS5154572A/ja active Pending
-
1976
- 1976-06-03 FR FR7616802A patent/FR2309536A1/fr active Granted
-
1977
- 1977-02-22 ES ES456168A patent/ES456168A1/es not_active Expired
- 1977-03-04 US US05/774,436 patent/US4150135A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DD123190A5 (el) | 1976-12-05 |
FI752516A (el) | 1976-03-10 |
GB1484431A (en) | 1977-09-01 |
AU8460875A (en) | 1977-03-17 |
DE2539907A1 (de) | 1976-03-25 |
US4150135A (en) | 1979-04-17 |
LU73348A1 (el) | 1976-08-13 |
IL48061A0 (en) | 1975-11-25 |
AU503631B2 (en) | 1979-09-13 |
IE41898L (en) | 1976-03-09 |
FR2309536A1 (fr) | 1976-11-26 |
ES456168A1 (es) | 1978-08-01 |
NL7510617A (nl) | 1976-03-11 |
AR208562A1 (es) | 1977-02-15 |
JPS5154572A (en) | 1976-05-13 |
ES440830A1 (es) | 1977-07-01 |
FR2283681A1 (fr) | 1976-04-02 |
DK401575A (da) | 1976-03-10 |
BE833212A (fr) | 1976-03-09 |
SE7509022L (sv) | 1976-03-10 |
IE41898B1 (en) | 1980-04-23 |
NO753062L (el) | 1976-03-10 |
SU682126A3 (ru) | 1979-08-25 |
FR2309536B1 (el) | 1979-07-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL46967A (en) | N-pyrrolidyl-, n-piperidyl-,n-pyridyl-and n-pyrroly-polyfluoroalkyl-benzamide derivatives, their preparation and pharmaceutical compositions comprising them | |
IL48642A0 (en) | 3-amino-indazolecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL47625A (en) | 4-heterocyclyl-6,7-dialkoxyquin-azoline derivatives and pharmaceutical compositions containing them | |
IL48593A (en) | 1-substituted-4-benzylidenepiperidine derivatives, their preparation and pharmaceutical compositions comprising them | |
IL47269A0 (en) | New phenylguanidine derivatives,their preparation and pharmaceutical compositions containing them | |
IL47314A0 (en) | New biphenylyl derivatives,their preparation and pharmaceutical compositions containing them | |
IL47529A0 (en) | New benzimidazolinone derivatives,their preparation and pharmaceutical compositions containing them | |
IL47360A (en) | -amino- and -formyl- -(p-acycloxyphenyl) acetamido-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL48069A0 (en) | New diazepine derivatives,their preparation and pharmaceutical compositions containing them | |
IL46505A0 (en) | New indole derivatives,their preparation and pharmaceutical compositions containing them | |
IL47877A0 (en) | Novel thienothiazine derivatives,their manufacture and pharmaceutical compositions containing them | |
IL48061A (en) | 4a-phenyl-cis-decahydroisoquinoline derivatives, their preparation and pharmaceutical compositions containing them | |
IL48502A0 (en) | Novel benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them | |
IL47329A0 (en) | New pyridobenzodiazepinones,their preparation and pharmaceutical compositions containing them | |
IL47015A (en) | Derivatives of phenthylamino-ketones and phenthylamino-dioxolanes,their preparation and pharmaceutical compositions containing them | |
IL48697A0 (en) | Novel xanthine derivatives,their preparation and pharmaceutical compositions containing them | |
IL47196A (en) | 7-substituted-8-aminomethyl-isoflavone derivatives, their preparation and pharmaceutical compositions containing them | |
IL47826A (en) | 7-aminoalkoxy-chroman and-tetrahydronaphthalene derivatives their preparation and pharmaceutical compositions containing them | |
IL47299A (en) | 3-thiomethyl-3-cephem-4-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
IL47892A0 (en) | Novel cinnamamide derivatives,their preparation and pharmaceutical compositions containing them | |
IL46957A0 (en) | Novel theophylline derivatives,their preparation and pharmaceutical compositions containing them | |
IL47519A (en) | 7-sulphinimidoyl(sulphimidoyl)-xanthone-2-carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
IL47155A0 (en) | New isoquinoline derivatives,their preparation and pharmaceutical compositions containing them | |
IL47522A0 (en) | Ergopeptine derivatives,their preparation and pharmaceutical compositions containing them | |
IL48526A (en) | 1-imidazolyl-1-phenoxy-3,3-butan-2-one(ol)derivatives,their preparation and pharmaceutical compositions containing them |