IL46451A - Di(heteroarylmethylthioalkyl guanidino thioureido isothioureidoor mainomethylamino)-alkanes - Google Patents

Di(heteroarylmethylthioalkyl guanidino thioureido isothioureidoor mainomethylamino)-alkanes

Info

Publication number
IL46451A
IL46451A IL46451A IL4645175A IL46451A IL 46451 A IL46451 A IL 46451A IL 46451 A IL46451 A IL 46451A IL 4645175 A IL4645175 A IL 4645175A IL 46451 A IL46451 A IL 46451A
Authority
IL
Israel
Prior art keywords
mainomethylamino
isothioureidoor
heteroarylmethylthioalkyl
thioureido
guanidino
Prior art date
Application number
IL46451A
Other languages
English (en)
Other versions
IL46451A0 (en
Inventor
C Genellin
G Durant
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL46451A0 publication Critical patent/IL46451A0/xx
Publication of IL46451A publication Critical patent/IL46451A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL46451A 1974-02-07 1975-01-17 Di(heteroarylmethylthioalkyl guanidino thioureido isothioureidoor mainomethylamino)-alkanes IL46451A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5596/74A GB1493931A (en) 1974-02-07 1974-02-07 Guanidines isothioureas and thioureas

Publications (2)

Publication Number Publication Date
IL46451A0 IL46451A0 (en) 1975-04-25
IL46451A true IL46451A (en) 1980-03-31

Family

ID=9799081

Family Applications (1)

Application Number Title Priority Date Filing Date
IL46451A IL46451A (en) 1974-02-07 1975-01-17 Di(heteroarylmethylthioalkyl guanidino thioureido isothioureidoor mainomethylamino)-alkanes

Country Status (20)

Country Link
US (3) US3968227A (fr)
JP (1) JPS5946219B2 (fr)
AU (1) AU500729B2 (fr)
BE (1) BE824923A (fr)
CA (1) CA1062263A (fr)
CH (1) CH615916A5 (fr)
DE (1) DE2504794A1 (fr)
DK (1) DK14475A (fr)
ES (2) ES434542A1 (fr)
FR (1) FR2260343B1 (fr)
GB (1) GB1493931A (fr)
HU (1) HU174066B (fr)
IE (1) IE40659B1 (fr)
IL (1) IL46451A (fr)
LU (1) LU71804A1 (fr)
NL (1) NL7500977A (fr)
NO (1) NO143315C (fr)
PL (1) PL98615B1 (fr)
SE (1) SE416050B (fr)
ZA (1) ZA75180B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4197305A (en) * 1974-02-07 1980-04-08 Smith Kline & French Laboratories Limited Thiazole, isothiazole, oxazole and isoxazole compounds
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
US4105770A (en) * 1975-07-31 1978-08-08 Smith Kline & French Laboratories Limited Heterocyclomethylsulphinylethyl derivatives of N-cyanoguanidines, thioureas and 2-amino-1-nitroethylene
ZA774221B (en) * 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
US4210652A (en) * 1976-07-28 1980-07-01 Smith Kline & French Laboratories Limited Pharmacologically active 1,3-bis[1-(2-heteroalkylthio)ethylamino)-2-nitrovinyl-1-amino]propane derivatives
ZA774220B (en) * 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
US4219553A (en) * 1976-07-28 1980-08-26 Smith Kline & French Laboratories Limited Alkoxy pyridyl substituted alkanes
GR62452B (en) 1977-04-20 1979-04-12 Ici Ltd Preparation process of guanidine derivatives
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4200760A (en) * 1978-09-26 1980-04-29 Bristol-Myers Company Imidazolylalkylthioalkylamino-ethylene derivatives
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
FR2446829A1 (fr) 1978-11-16 1980-08-14 Glaxo Group Ltd Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide
CA2927544A1 (fr) 2015-04-24 2016-10-24 Wal-Mart Stores, Inc. Methode et appareil de support de contenants ouverts
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB850483A (en) * 1957-10-25 1960-10-05 May & Baker Ltd Improvements in or relating to pyrimidine derivatives
US3622596A (en) * 1960-10-14 1971-11-23 A Wander Sa Dr Carbanilide compounds
DE1214239B (de) * 1960-11-01 1966-04-14 Spofa Sdruzeni Podnikuu Pro Zd Verfahren zur Herstellung von 5-bis-(beta-Chloraethyl)-aminomethyluracil-hydrochlorid
CH405282A (de) * 1961-11-24 1966-01-15 Wander Ag Dr A Verfahren zur Herstellung basischer Verbindungen
US3225047A (en) * 1964-02-24 1965-12-21 Bristol Myers Co N,n'-bis(pyrimidine-5-acetyl)ethylene diamines
CH440252A (de) * 1964-04-24 1967-07-31 Wander Ag Dr A Verfahren zur Herstellung neuer Harnstoffderivate
US3335142A (en) * 1965-07-07 1967-08-08 American Cyanamid Co Process for the preparation of n, n'-disubstituted ureas
US3646049A (en) * 1970-03-05 1972-02-29 Merck & Co Inc Acylaminobenzimidazole derivatives
US4137234A (en) * 1971-03-09 1979-01-30 Smith Kline & French Laboratories Limited Thiazole, isothiazole, oxazole and isoxazole substituted thiourea and urea compounds
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US3917626A (en) * 1971-03-29 1975-11-04 Ici Ltd 3,6-Dioxa-1,8-octandiamido bis (pyridinium) compounds
GB1339764A (en) * 1971-03-29 1973-12-05 Ici Ltd Pyridine derivatives
US4070472A (en) * 1974-02-07 1978-01-24 Smith Kline & French Laboratories Limited Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine
US4133886A (en) * 1974-02-07 1979-01-09 Smith Kline & French Laboratories Limited Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
GB1497260A (en) * 1974-06-28 1978-01-05 Smith Kline French Lab Guanidine derivatives
US4151289A (en) * 1975-01-22 1979-04-24 Smith Kline & French Laboratories Limited Nitromethylene amidino derivatives containing imidazole groups

Also Published As

Publication number Publication date
US4578388A (en) 1986-03-25
US4301165A (en) 1981-11-17
PL98615B1 (pl) 1978-05-31
US3968227A (en) 1976-07-06
ES437587A1 (es) 1977-01-16
JPS5946219B2 (ja) 1984-11-10
JPS50108259A (fr) 1975-08-26
NL7500977A (nl) 1975-08-11
SE7501208L (fr) 1975-08-08
ZA75180B (en) 1976-01-28
BE824923A (fr) 1975-07-29
DK14475A (fr) 1975-10-13
IL46451A0 (en) 1975-04-25
AU7746375A (en) 1976-07-22
CH615916A5 (fr) 1980-02-29
HU174066B (hu) 1979-10-28
FR2260343B1 (fr) 1978-07-21
FR2260343A1 (fr) 1975-09-05
DE2504794A1 (de) 1975-08-14
CA1062263A (fr) 1979-09-11
AU500729B2 (en) 1979-05-31
NO143315B (no) 1980-10-06
NO750391L (fr) 1975-09-01
IE40659L (en) 1975-08-07
ES434542A1 (es) 1976-12-16
LU71804A1 (fr) 1975-06-24
GB1493931A (en) 1977-11-30
NO143315C (no) 1981-01-14
IE40659B1 (en) 1979-07-18
SE416050B (sv) 1980-11-24

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