IL45609A - Substituted isoquinoline 1,3-dione derivatives their preparation and pharmaceutical compositions containing them - Google Patents
Substituted isoquinoline 1,3-dione derivatives their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL45609A IL45609A IL45609A IL4560974A IL45609A IL 45609 A IL45609 A IL 45609A IL 45609 A IL45609 A IL 45609A IL 4560974 A IL4560974 A IL 4560974A IL 45609 A IL45609 A IL 45609A
- Authority
- IL
- Israel
- Prior art keywords
- group
- formula
- compounds
- acid addition
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2345422A DE2345422C2 (de) | 1973-09-08 | 1973-09-08 | Substituierte Isochinolyl-arylpiperazine diese enthaltende Arzneimittel sowie Verfahren zu deren Herstellung |
DE19732345423 DE2345423A1 (de) | 1973-09-08 | 1973-09-08 | Neue substituierte phenylaethylaminderivate, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu deren herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
IL45609A0 IL45609A0 (en) | 1974-11-29 |
IL45609A true IL45609A (en) | 1977-07-31 |
Family
ID=25765764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL45609A IL45609A (en) | 1973-09-08 | 1974-09-06 | Substituted isoquinoline 1,3-dione derivatives their preparation and pharmaceutical compositions containing them |
Country Status (26)
Country | Link |
---|---|
US (1) | US3948898A (fr) |
JP (1) | JPS596868B2 (fr) |
AT (1) | AT330777B (fr) |
BG (2) | BG22390A3 (fr) |
CA (1) | CA1025869A (fr) |
CH (2) | CH605779A5 (fr) |
CS (1) | CS185660B2 (fr) |
DD (1) | DD115122A5 (fr) |
DK (1) | DK137124C (fr) |
ES (3) | ES429473A1 (fr) |
FI (1) | FI52219C (fr) |
FR (1) | FR2242979B1 (fr) |
GB (1) | GB1446791A (fr) |
HK (1) | HK4180A (fr) |
HU (1) | HU167869B (fr) |
IE (1) | IE40742B1 (fr) |
IL (1) | IL45609A (fr) |
MY (1) | MY8100330A (fr) |
NL (1) | NL176363C (fr) |
NO (1) | NO140978C (fr) |
PH (1) | PH12918A (fr) |
PL (1) | PL91712B1 (fr) |
RO (1) | RO63655A (fr) |
SE (1) | SE424863B (fr) |
SU (2) | SU545256A3 (fr) |
YU (1) | YU39928B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2639718C2 (de) * | 1976-09-03 | 1987-03-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | 1-[6,7-Dimethoxy-3,4-dihydro-2H-isochinolin-1-on-2-yl]-3-[N-methyl-N-(2-(3,4-dimethoxy-phenyl)-äthyl)-amino]-propan, dessen physiologisch verträgliche Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
DE2702600A1 (de) * | 1977-01-22 | 1978-07-27 | Thomae Gmbh Dr K | Neue aminoalkoxyphenyl-derivate |
US4619930A (en) * | 1985-01-16 | 1986-10-28 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use |
JPS6312877U (fr) * | 1986-03-05 | 1988-01-27 | ||
US4876256A (en) * | 1988-04-29 | 1989-10-24 | Merck & Co., Inc. | Alkylpiperazinylpyridines as hypoglycemic agents |
US5169948A (en) * | 1991-05-22 | 1992-12-08 | American Home Products Corporation | Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors |
SE9303274D0 (sv) * | 1993-10-07 | 1993-10-07 | Astra Ab | Novel phenylethyl and phenylproplamines |
EP1491532B1 (fr) | 1997-10-27 | 2010-12-15 | NeuroSearch A/S | Diazacycloalcanes d'hetero-aryle utilises en tant que ligands cholinergiques des recepteurs nicotiniques de l'acetylcholine |
US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
ATE517880T1 (de) * | 2005-01-28 | 2011-08-15 | Boehringer Ingelheim Pharma | Verfahren zur herstellung von isochroman und derivaten davon |
US8927546B2 (en) | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
SG171634A1 (en) * | 2006-02-28 | 2011-06-29 | Helicon Therapeutics Inc | Therapeutic piperazines as pde4 inhibitors |
WO2023288039A1 (fr) * | 2021-07-16 | 2023-01-19 | Denali Therapeutics Inc. | Composés, compositions et procédés |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1185934A (en) * | 1967-06-28 | 1970-03-25 | Pfizer & Co C | Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof |
SE368009B (fr) * | 1971-09-16 | 1974-06-17 | Kabi Ab | |
GB1424348A (en) * | 1972-11-30 | 1976-02-11 | Wyeth John & Brother Ltd | Isoquinoline derivatives |
-
1974
- 1974-08-08 AT AT651474A patent/AT330777B/de active
- 1974-08-21 FI FI742465A patent/FI52219C/fi active
- 1974-08-23 ES ES429473A patent/ES429473A1/es not_active Expired
- 1974-09-04 IE IE1838/74A patent/IE40742B1/xx unknown
- 1974-09-04 BG BG27624A patent/BG22390A3/xx unknown
- 1974-09-04 BG BG7428726A patent/BG26195A4/xx unknown
- 1974-09-04 US US05/503,072 patent/US3948898A/en not_active Expired - Lifetime
- 1974-09-05 YU YU2391/74A patent/YU39928B/xx unknown
- 1974-09-06 HU HUTO980A patent/HU167869B/hu unknown
- 1974-09-06 CH CH1601477A patent/CH605779A5/xx not_active IP Right Cessation
- 1974-09-06 GB GB3908374A patent/GB1446791A/en not_active Expired
- 1974-09-06 CA CA208,607A patent/CA1025869A/fr not_active Expired
- 1974-09-06 CH CH1218974A patent/CH605778A5/xx not_active IP Right Cessation
- 1974-09-06 PH PH16248A patent/PH12918A/en unknown
- 1974-09-06 FR FR7430387A patent/FR2242979B1/fr not_active Expired
- 1974-09-06 SE SE7411312A patent/SE424863B/xx not_active IP Right Cessation
- 1974-09-06 IL IL45609A patent/IL45609A/en unknown
- 1974-09-06 RO RO7400079932A patent/RO63655A/fr unknown
- 1974-09-06 DD DD180966A patent/DD115122A5/xx unknown
- 1974-09-06 DK DK472774A patent/DK137124C/da not_active IP Right Cessation
- 1974-09-06 CS CS7400006150A patent/CS185660B2/cs unknown
- 1974-09-06 NL NLAANVRAGE7411843,A patent/NL176363C/xx not_active IP Right Cessation
- 1974-09-06 NO NO743220A patent/NO140978C/no unknown
- 1974-09-06 JP JP49102862A patent/JPS596868B2/ja not_active Expired
- 1974-09-07 PL PL1974173958A patent/PL91712B1/pl unknown
-
1975
- 1975-01-20 ES ES433959A patent/ES433959A1/es not_active Expired
- 1975-01-20 ES ES433958A patent/ES433958A1/es not_active Expired
- 1975-06-20 SU SU2145935A patent/SU545256A3/ru active
- 1975-06-20 SU SU2145942A patent/SU538664A3/ru active
-
1980
- 1980-01-31 HK HK41/80A patent/HK4180A/xx unknown
-
1981
- 1981-12-30 MY MY330/81A patent/MY8100330A/xx unknown
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