IL45158A0 - Piperazinyl-quinoxalines,derivatives and processes for their preparation - Google Patents

Piperazinyl-quinoxalines,derivatives and processes for their preparation

Info

Publication number
IL45158A0
IL45158A0 IL45158A IL4515874A IL45158A0 IL 45158 A0 IL45158 A0 IL 45158A0 IL 45158 A IL45158 A IL 45158A IL 4515874 A IL4515874 A IL 4515874A IL 45158 A0 IL45158 A0 IL 45158A0
Authority
IL
Israel
Prior art keywords
quinoxalines
piperazinyl
derivatives
processes
preparation
Prior art date
Application number
IL45158A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL45158A0 publication Critical patent/IL45158A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL45158A 1973-07-13 1974-07-01 Piperazinyl-quinoxalines,derivatives and processes for their preparation IL45158A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37902273A 1973-07-13 1973-07-13
US46538174A 1974-04-29 1974-04-29

Publications (1)

Publication Number Publication Date
IL45158A0 true IL45158A0 (en) 1974-11-29

Family

ID=27008442

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45158A IL45158A0 (en) 1973-07-13 1974-07-01 Piperazinyl-quinoxalines,derivatives and processes for their preparation

Country Status (18)

Country Link
JP (1) JPS5037791A (fr)
AU (1) AU7073174A (fr)
BG (1) BG21606A3 (fr)
CH (1) CH605919A5 (fr)
DD (1) DD112127A5 (fr)
DE (1) DE2433397A1 (fr)
DK (1) DK342674A (fr)
ES (1) ES428107A1 (fr)
FI (1) FI193974A (fr)
FR (1) FR2236499B1 (fr)
GB (1) GB1440722A (fr)
IE (1) IE39869B1 (fr)
IL (1) IL45158A0 (fr)
LU (1) LU70510A1 (fr)
NL (1) NL7408705A (fr)
NO (1) NO742351L (fr)
RO (1) RO63539A (fr)
SE (1) SE417316B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082845A (en) * 1977-04-25 1978-04-04 Merck & Co., Inc. 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4107309A (en) * 1977-05-23 1978-08-15 American Cyanamid Company Substituted imidazo[1,2-d]-as-triazines
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
EP0094498A3 (fr) * 1982-05-06 1985-04-03 American Cyanamid Company Dérivés de 1-pipérazine utiles contre l'arthériosclérose
ES2042395B1 (es) * 1992-02-27 1994-06-16 Promotora Catalana De Inversio Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
FR2731221B1 (fr) * 1995-03-01 1997-05-30 Pf Medicament Nouveaux derives de l'ethyl-1 dihydro-1, 2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
WO1999021850A1 (fr) * 1997-10-24 1999-05-06 Neurogen Corporation Piperazines de 1-(2-naphtyle) et de 1-(2-azanaphtyle)-4-(1-phenylmethyle)en tant que ligands pour le sous-type du recepteur de la dopamine d¿4?
US6040448A (en) 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
WO2000012500A2 (fr) * 1998-09-02 2000-03-09 Neurogen Corporation 2-aryl-4-[4-heteroaryl]piperazin-1-yl methylimidazoles: ligands pour le sous-type de recepteur d4 de la dopamine
SE9901884D0 (sv) * 1999-05-21 1999-05-21 Pharmacia & Upjohn Ab Novel compounds their use and preparation
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
WO2000076984A2 (fr) * 1999-05-21 2000-12-21 Biovitrum Ab Nouveaux composes, et utilisation et preparation de ces derniers
JP4707261B2 (ja) * 2001-05-15 2011-06-22 日本エンバイロケミカルズ株式会社 キノキサリン系化合物および工業用殺菌組成物
ATE454383T1 (de) 2002-06-19 2010-01-15 Biovitrum Ab Publ Neue verbindungen, deren verwendung und herstellung
WO2004009586A1 (fr) * 2002-07-19 2004-01-29 Biovitrum Ab Nouveaux derives de piperazinyl-pyrazinone pour le traitement des troubles lies au recepteur 5-ht2a
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds
AU2004221812B2 (en) 2003-03-19 2010-02-18 Exelixis Inc. Tie-2 modulators and methods of use
MXPA06003578A (es) * 2003-09-30 2006-08-31 Johnson & Johnson Compuestos de quinoxalina.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL260335A (fr) * 1960-01-22
CH450434A (de) * 1961-12-14 1968-01-31 Ciba Geigy Verfahren zur Herstellung von Diazinen
BE788451A (fr) * 1971-09-08 1973-03-06 Bayer Ag Nouvelles 2-amino-quinoxalines, leur procede de preparation et leur application comme insecticides, acaricides et fongicides
GB1457400A (en) * 1972-11-20 1976-12-01 Pfizer Pharmaceutical compositions containing 2-substituted quinoxa lines

Also Published As

Publication number Publication date
AU7073174A (en) 1976-01-08
NL7408705A (nl) 1975-01-15
IE39869B1 (en) 1979-01-17
RO63539A (fr) 1978-07-15
ES428107A1 (es) 1976-11-16
SE417316B (sv) 1981-03-09
IE39869L (en) 1975-01-13
JPS5037791A (fr) 1975-04-08
DD112127A5 (fr) 1975-03-20
NO742351L (fr) 1975-02-10
GB1440722A (en) 1976-06-23
FR2236499B1 (fr) 1977-04-15
CH605919A5 (fr) 1978-10-13
DE2433397A1 (de) 1975-02-06
LU70510A1 (fr) 1975-03-27
FI193974A (fr) 1975-01-14
SE7408486L (sv) 1975-01-14
BG21606A3 (fr) 1976-07-20
FR2236499A1 (fr) 1975-02-07
DK342674A (fr) 1975-03-03

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