FR2236499A1 - - Google Patents

Info

Publication number
FR2236499A1
FR2236499A1 FR7424114A FR7424114A FR2236499A1 FR 2236499 A1 FR2236499 A1 FR 2236499A1 FR 7424114 A FR7424114 A FR 7424114A FR 7424114 A FR7424114 A FR 7424114A FR 2236499 A1 FR2236499 A1 FR 2236499A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7424114A
Other versions
FR2236499B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2236499A1 publication Critical patent/FR2236499A1/fr
Application granted granted Critical
Publication of FR2236499B1 publication Critical patent/FR2236499B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7424114A 1973-07-13 1974-07-11 Expired FR2236499B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37902273A 1973-07-13 1973-07-13
US46538174A 1974-04-29 1974-04-29

Publications (2)

Publication Number Publication Date
FR2236499A1 true FR2236499A1 (fr) 1975-02-07
FR2236499B1 FR2236499B1 (fr) 1977-04-15

Family

ID=27008442

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7424114A Expired FR2236499B1 (fr) 1973-07-13 1974-07-11

Country Status (18)

Country Link
JP (1) JPS5037791A (fr)
AU (1) AU7073174A (fr)
BG (1) BG21606A3 (fr)
CH (1) CH605919A5 (fr)
DD (1) DD112127A5 (fr)
DE (1) DE2433397A1 (fr)
DK (1) DK342674A (fr)
ES (1) ES428107A1 (fr)
FI (1) FI193974A (fr)
FR (1) FR2236499B1 (fr)
GB (1) GB1440722A (fr)
IE (1) IE39869B1 (fr)
IL (1) IL45158A0 (fr)
LU (1) LU70510A1 (fr)
NL (1) NL7408705A (fr)
NO (1) NO742351L (fr)
RO (1) RO63539A (fr)
SE (1) SE417316B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094498A2 (fr) * 1982-05-06 1983-11-23 American Cyanamid Company Dérivés de 1-pipérazine utiles contre l'arthériosclérose
ES2042395A1 (es) * 1992-02-27 1993-12-01 Promotora Catalana De Inversio Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
WO1996026928A1 (fr) * 1995-03-01 1996-09-06 Pierre Fabre Medicament Nouveaux derives de l'ethyl-1 dihydro-1,2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082845A (en) * 1977-04-25 1978-04-04 Merck & Co., Inc. 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4107309A (en) * 1977-05-23 1978-08-15 American Cyanamid Company Substituted imidazo[1,2-d]-as-triazines
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
WO1999021850A1 (fr) * 1997-10-24 1999-05-06 Neurogen Corporation Piperazines de 1-(2-naphtyle) et de 1-(2-azanaphtyle)-4-(1-phenylmethyle)en tant que ligands pour le sous-type du recepteur de la dopamine d¿4?
US6040448A (en) 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
WO2000012500A2 (fr) * 1998-09-02 2000-03-09 Neurogen Corporation 2-aryl-4-[4-heteroaryl]piperazin-1-yl methylimidazoles: ligands pour le sous-type de recepteur d4 de la dopamine
SE9901884D0 (sv) * 1999-05-21 1999-05-21 Pharmacia & Upjohn Ab Novel compounds their use and preparation
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
WO2000076984A2 (fr) * 1999-05-21 2000-12-21 Biovitrum Ab Nouveaux composes, et utilisation et preparation de ces derniers
JP4707261B2 (ja) * 2001-05-15 2011-06-22 日本エンバイロケミカルズ株式会社 キノキサリン系化合物および工業用殺菌組成物
ATE454383T1 (de) 2002-06-19 2010-01-15 Biovitrum Ab Publ Neue verbindungen, deren verwendung und herstellung
WO2004009586A1 (fr) * 2002-07-19 2004-01-29 Biovitrum Ab Nouveaux derives de piperazinyl-pyrazinone pour le traitement des troubles lies au recepteur 5-ht2a
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds
AU2004221812B2 (en) 2003-03-19 2010-02-18 Exelixis Inc. Tie-2 modulators and methods of use
MXPA06003578A (es) * 2003-09-30 2006-08-31 Johnson & Johnson Compuestos de quinoxalina.

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1425262A (fr) * 1960-01-22 1966-01-24 Bayer Ag Procédé de fabrication de quinoxalines
US3250770A (en) * 1961-12-14 1966-05-10 Ciba Geigy Corp Synthesis of 1:4-diazines
FR2152232A5 (fr) * 1971-09-08 1973-04-20 Bayer Ag
FR2206951A1 (fr) * 1972-11-20 1974-06-14 Pfizer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1425262A (fr) * 1960-01-22 1966-01-24 Bayer Ag Procédé de fabrication de quinoxalines
US3250770A (en) * 1961-12-14 1966-05-10 Ciba Geigy Corp Synthesis of 1:4-diazines
FR2152232A5 (fr) * 1971-09-08 1973-04-20 Bayer Ag
FR2206951A1 (fr) * 1972-11-20 1974-06-14 Pfizer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094498A2 (fr) * 1982-05-06 1983-11-23 American Cyanamid Company Dérivés de 1-pipérazine utiles contre l'arthériosclérose
EP0094498A3 (fr) * 1982-05-06 1985-04-03 American Cyanamid Company Dérivés de 1-pipérazine utiles contre l'arthériosclérose
ES2042395A1 (es) * 1992-02-27 1993-12-01 Promotora Catalana De Inversio Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
WO1996026928A1 (fr) * 1995-03-01 1996-09-06 Pierre Fabre Medicament Nouveaux derives de l'ethyl-1 dihydro-1,2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
FR2731221A1 (fr) * 1995-03-01 1996-09-06 Pf Medicament Nouveaux derives de l'ethyl-1 dihydro-1, 2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
AU707032B2 (en) * 1995-03-01 1999-07-01 Pierre Fabre Medicament Novel 1-ethyl-1,2-dihydro-2-oxo-3-methylamino-quinoxaline derivatives, their use as medicinal products and the pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
AU7073174A (en) 1976-01-08
NL7408705A (nl) 1975-01-15
IE39869B1 (en) 1979-01-17
RO63539A (fr) 1978-07-15
ES428107A1 (es) 1976-11-16
SE417316B (sv) 1981-03-09
IE39869L (en) 1975-01-13
JPS5037791A (fr) 1975-04-08
DD112127A5 (fr) 1975-03-20
NO742351L (fr) 1975-02-10
IL45158A0 (en) 1974-11-29
GB1440722A (en) 1976-06-23
FR2236499B1 (fr) 1977-04-15
CH605919A5 (fr) 1978-10-13
DE2433397A1 (de) 1975-02-06
LU70510A1 (fr) 1975-03-27
FI193974A (fr) 1975-01-14
SE7408486L (sv) 1975-01-14
BG21606A3 (fr) 1976-07-20
DK342674A (fr) 1975-03-03

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Legal Events

Date Code Title Description
ST Notification of lapse