IL44166A - Imidazo(4,5-f)quinolines and their preparation - Google Patents
Imidazo(4,5-f)quinolines and their preparationInfo
- Publication number
- IL44166A IL44166A IL44166A IL4416674A IL44166A IL 44166 A IL44166 A IL 44166A IL 44166 A IL44166 A IL 44166A IL 4416674 A IL4416674 A IL 4416674A IL 44166 A IL44166 A IL 44166A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- phenyl
- chloro
- hydroxyphenyl
- chlorophenyl
- Prior art date
Links
- UYVFEZBIQHCLBF-UHFFFAOYSA-N 3h-imidazo[4,5-f]quinoline Chemical class C1=CC=C2C(N=CN3)=C3C=CC2=N1 UYVFEZBIQHCLBF-UHFFFAOYSA-N 0.000 title 1
- -1 9-(substituted amino)imidazo[4,5-f]quinolines Chemical class 0.000 claims abstract 27
- 150000001875 compounds Chemical class 0.000 claims 20
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 125000004208 3-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C([H])C(*)=C1[H] 0.000 claims 3
- 125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 claims 3
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims 3
- MNCMBBIFTVWHIP-UHFFFAOYSA-N 1-anthracen-9-yl-2,2,2-trifluoroethanone Chemical group C1=CC=C2C(C(=O)C(F)(F)F)=C(C=CC=C3)C3=CC2=C1 MNCMBBIFTVWHIP-UHFFFAOYSA-N 0.000 claims 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 claims 2
- 125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 claims 2
- 125000004860 4-ethylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])C([H])([H])[H] 0.000 claims 2
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 claims 2
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical group NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 claims 2
- 150000001412 amines Chemical class 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 208000004926 Bacterial Vaginosis Diseases 0.000 abstract 1
- 241000207201 Gardnerella vaginalis Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US367498A US3878206A (en) | 1973-06-06 | 1973-06-06 | 9-(Substituted amino)imidazo{8 4,5-f{9 quinolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL44166A0 IL44166A0 (en) | 1974-05-16 |
| IL44166A true IL44166A (en) | 1976-08-31 |
Family
ID=23447415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL44166A IL44166A (en) | 1973-06-06 | 1974-02-07 | Imidazo(4,5-f)quinolines and their preparation |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3878206A (da) |
| JP (1) | JPS5738593B2 (da) |
| AU (1) | AU473160B2 (da) |
| BE (1) | BE816004A (da) |
| CH (1) | CH598257A5 (da) |
| DE (1) | DE2427410A1 (da) |
| DK (1) | DK133104C (da) |
| FR (1) | FR2232318B1 (da) |
| GB (1) | GB1402243A (da) |
| IL (1) | IL44166A (da) |
| NL (1) | NL7406572A (da) |
| SE (1) | SE391926B (da) |
| ZA (1) | ZA74798B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR65025B (en) * | 1977-07-21 | 1980-06-16 | Thomae Gmbh Dr K | Method for the preparation of new imidazo-isokinolin-diones |
| DE3269743D1 (en) * | 1981-12-14 | 1986-04-10 | Norwich Eaton Pharma | Use of the compound 9-(p-(n-methylacetamido)anilino)-7-methyl-1h-imidazo(4,5-f)quinoline hydrochloride (i) as antitumor agent |
| JPS6017589U (ja) * | 1983-07-15 | 1985-02-06 | 三菱電機株式会社 | 避雷器の自動切離し装置 |
| US4716168A (en) * | 1985-01-08 | 1987-12-29 | Norwich Eaton Pharmaceuticals, Inc. | Imidazo(4,5-f)quinolines useful as immunomodulating agents |
| EP0187705A3 (en) * | 1985-01-08 | 1988-05-11 | Norwich Eaton Pharmaceuticals, Inc. | Imidazo(4,5-f)quinolines useful as immunomodulating agents |
| WO2002045706A2 (en) * | 2000-12-05 | 2002-06-13 | Quest Medicine, Inc. | The use of polymers for inactivating pathogens |
| KR100453946B1 (ko) * | 2002-10-11 | 2004-10-20 | (주) 비엔씨바이오팜 | 6-메틸피리딘 유도체, 그 제조방법 및 이를 포함하는 항바이러스용 약학적 조성물 |
| DK1569896T3 (da) * | 2002-12-06 | 2007-12-10 | Xention Ltd | Tetrahydronaphthalenderivater |
| DK1572632T3 (da) * | 2002-12-09 | 2008-10-27 | Xention Ltd | Tetrahydro-naphthalenderivater som vanilloidreceptorantagonister |
| GB0516564D0 (en) * | 2005-08-12 | 2005-09-21 | Ge Healthcare Ltd | Fluorination process |
-
1973
- 1973-06-06 US US367498A patent/US3878206A/en not_active Expired - Lifetime
-
1974
- 1974-02-06 ZA ZA00740798A patent/ZA74798B/xx unknown
- 1974-02-07 IL IL44166A patent/IL44166A/en unknown
- 1974-02-11 AU AU65452/74A patent/AU473160B2/en not_active Expired
- 1974-02-26 GB GB871774A patent/GB1402243A/en not_active Expired
- 1974-04-26 SE SE7405653A patent/SE391926B/xx unknown
- 1974-05-15 CH CH665074A patent/CH598257A5/xx not_active IP Right Cessation
- 1974-05-16 NL NL7406572A patent/NL7406572A/xx not_active Application Discontinuation
- 1974-05-27 JP JP5887974A patent/JPS5738593B2/ja not_active Expired
- 1974-06-05 FR FR7419424A patent/FR2232318B1/fr not_active Expired
- 1974-06-06 BE BE145153A patent/BE816004A/xx unknown
- 1974-06-06 DE DE19742427410 patent/DE2427410A1/de active Pending
- 1974-06-06 DK DK302074A patent/DK133104C/da active
Also Published As
| Publication number | Publication date |
|---|---|
| SE7405653L (da) | 1974-12-09 |
| US3878206A (en) | 1975-04-15 |
| DK302074A (da) | 1975-02-03 |
| SE391926B (sv) | 1977-03-07 |
| JPS5738593B2 (da) | 1982-08-16 |
| AU6545274A (en) | 1975-08-14 |
| GB1402243A (en) | 1975-08-06 |
| JPS5019775A (da) | 1975-03-01 |
| NL7406572A (da) | 1974-12-10 |
| DK133104C (da) | 1976-08-23 |
| FR2232318B1 (da) | 1977-07-08 |
| CH598257A5 (da) | 1978-04-28 |
| DE2427410A1 (de) | 1975-01-09 |
| DK133104B (da) | 1976-03-22 |
| BE816004A (fr) | 1974-12-06 |
| IL44166A0 (en) | 1974-05-16 |
| AU473160B2 (en) | 1976-06-17 |
| FR2232318A1 (da) | 1975-01-03 |
| ZA74798B (en) | 1975-09-24 |
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