IL44109A - Capsules and their manufacture - Google Patents
Capsules and their manufactureInfo
- Publication number
- IL44109A IL44109A IL44109A IL4410974A IL44109A IL 44109 A IL44109 A IL 44109A IL 44109 A IL44109 A IL 44109A IL 4410974 A IL4410974 A IL 4410974A IL 44109 A IL44109 A IL 44109A
- Authority
- IL
- Israel
- Prior art keywords
- capsule
- cap
- film
- forming material
- pins
- Prior art date
Links
- 239000002775 capsule Substances 0.000 title claims 16
- 238000004519 manufacturing process Methods 0.000 title claims 4
- 239000000463 material Substances 0.000 claims 14
- 238000000034 method Methods 0.000 claims 5
- 230000001464 adherent effect Effects 0.000 claims 4
- 108010010803 Gelatin Proteins 0.000 claims 3
- 238000007598 dipping method Methods 0.000 claims 3
- 238000004090 dissolution Methods 0.000 claims 3
- 229920000159 gelatin Polymers 0.000 claims 3
- 239000008273 gelatin Substances 0.000 claims 3
- 235000019322 gelatine Nutrition 0.000 claims 3
- 235000011852 gelatine desserts Nutrition 0.000 claims 3
- 229920000623 Cellulose acetate phthalate Polymers 0.000 claims 2
- ISAOCJYIOMOJEB-UHFFFAOYSA-N benzoin Chemical compound C=1C=CC=CC=1C(O)C(=O)C1=CC=CC=C1 ISAOCJYIOMOJEB-UHFFFAOYSA-N 0.000 claims 2
- 229940081734 cellulose acetate phthalate Drugs 0.000 claims 2
- 238000001035 drying Methods 0.000 claims 2
- ZQBAKBUEJOMQEX-UHFFFAOYSA-N phenyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OC1=CC=CC=C1 ZQBAKBUEJOMQEX-UHFFFAOYSA-N 0.000 claims 2
- 241000272470 Circus Species 0.000 claims 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims 1
- 229920001800 Shellac Polymers 0.000 claims 1
- 229920002125 Sokalan® Polymers 0.000 claims 1
- 244000028419 Styrax benzoin Species 0.000 claims 1
- 235000000126 Styrax benzoin Nutrition 0.000 claims 1
- 235000008411 Sumatra benzointree Nutrition 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 150000005215 alkyl ethers Chemical class 0.000 claims 1
- 229960002130 benzoin Drugs 0.000 claims 1
- ULBTUVJTXULMLP-UHFFFAOYSA-N butyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCC ULBTUVJTXULMLP-UHFFFAOYSA-N 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 238000005520 cutting process Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 210000004051 gastric juice Anatomy 0.000 claims 1
- 239000007903 gelatin capsule Substances 0.000 claims 1
- 235000019382 gum benzoic Nutrition 0.000 claims 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 claims 1
- 229940044600 maleic anhydride Drugs 0.000 claims 1
- 229920000609 methyl cellulose Polymers 0.000 claims 1
- 239000001923 methylcellulose Substances 0.000 claims 1
- 235000010981 methylcellulose Nutrition 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229960000969 phenyl salicylate Drugs 0.000 claims 1
- XNGIFLGASWRNHJ-UHFFFAOYSA-L phthalate(2-) Chemical compound [O-]C(=O)C1=CC=CC=C1C([O-])=O XNGIFLGASWRNHJ-UHFFFAOYSA-L 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- NQLVQOSNDJXLKG-UHFFFAOYSA-N prosulfocarb Chemical compound CCCN(CCC)C(=O)SCC1=CC=CC=C1 NQLVQOSNDJXLKG-UHFFFAOYSA-N 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 239000004208 shellac Substances 0.000 claims 1
- 229940113147 shellac Drugs 0.000 claims 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims 1
- 235000013874 shellac Nutrition 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/074—Filling capsules; Related operations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/077—Manufacturing capsule shells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
- B29C41/14—Dipping a core
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Manufacturing & Machinery (AREA)
- Mechanical Engineering (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB714173A GB1455884A (en) | 1973-02-14 | 1973-02-14 | Production of capsules |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL44109A0 IL44109A0 (en) | 1974-05-16 |
| IL44109A true IL44109A (en) | 1976-10-31 |
Family
ID=9827403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL44109A IL44109A (en) | 1973-02-14 | 1974-01-29 | Capsules and their manufacture |
Country Status (19)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4581875A (en) * | 1983-06-20 | 1986-04-15 | Cosden Technology, Inc. | Process for forming tamper-resistant tamper-indicative capsules |
| JPH01232963A (ja) * | 1988-03-14 | 1989-09-18 | Arimento Kogyo Kk | 重層軟カプセルの製造方法 |
| AT397764B (de) * | 1992-07-23 | 1994-06-27 | Schlegel Christoph | Kapselöffnungs- und -entleerungsautomat |
| TW245641B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1993-04-26 | 1995-04-21 | Takeda Pharm Industry Co | |
| FR2771660B1 (fr) * | 1997-11-28 | 2000-01-14 | Industrialisation Concept Et M | Procede pour former et deposer une dose determinee d'un produit liquide ou pateux et installation pour la mise en oeuvre du procede |
| GB0003424D0 (en) * | 2000-02-16 | 2000-04-05 | Bioprogress Tech Int Inc | A controlled release capsule |
| GB2398499B (en) * | 2000-02-16 | 2004-11-24 | Bioprogress Technology Ltd | Two layer capsules |
| DE102009010091A1 (de) * | 2009-02-24 | 2010-08-26 | Beiersdorf Ag | Stabilisierte Peelingkapsel |
| JP6195173B2 (ja) | 2011-10-06 | 2017-09-13 | コンボキャップ，インコーポレイティド | カプセルを製造する方法および装置 |
| CN104905967B (zh) * | 2015-05-23 | 2019-04-16 | 浙江益立胶囊股份有限公司 | 用于双层肠溶空心胶囊的生产模具 |
| EP4464313A3 (en) | 2020-11-25 | 2025-02-26 | Capsugel Belgium NV | Double layered delayed-release hard capsules |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB493934A (en) * | 1936-01-17 | 1938-10-17 | Hugo Remmler Ag Dr | Improvements in and relating to methods of treating medicaments |
| GB638284A (en) * | 1946-03-25 | 1950-06-07 | Parke Davis & Co | Improvements in or relating to enteric capsules |
-
1973
- 1973-02-14 GB GB714173A patent/GB1455884A/en not_active Expired
-
1974
- 1974-01-22 CA CA190,680A patent/CA1028951A/en not_active Expired
- 1974-01-24 IE IE143/74A patent/IE38792B1/xx unknown
- 1974-01-25 ZA ZA00740543A patent/ZA74543B/xx unknown
- 1974-01-29 IL IL44109A patent/IL44109A/en unknown
- 1974-02-04 HU HU74LI00000249A patent/HU172393B/hu unknown
- 1974-02-07 FR FR7404059A patent/FR2216985B1/fr not_active Expired
- 1974-02-08 DE DE19742406021 patent/DE2406021A1/de not_active Ceased
- 1974-02-11 SE SE7401793A patent/SE413836B/xx unknown
- 1974-02-11 NL NL7401812A patent/NL7401812A/xx not_active Application Discontinuation
- 1974-02-12 DD DD176513A patent/DD109509A5/xx unknown
- 1974-02-13 JP JP49017489A patent/JPS5029734A/ja active Pending
- 1974-02-13 BE BE6044458A patent/BE810991A/xx not_active IP Right Cessation
- 1974-02-13 AT AT113274A patent/AT336794B/de not_active IP Right Cessation
- 1974-02-13 YU YU00367/74A patent/YU36774A/xx unknown
- 1974-02-14 ES ES423259A patent/ES423259A1/es not_active Expired
- 1974-02-14 DK DK78174AA patent/DK137166B/da not_active IP Right Cessation
- 1974-02-14 CH CH207474A patent/CH592447A5/xx not_active IP Right Cessation
- 1974-02-14 CS CS741086A patent/CS191908B2/cs unknown
-
1976
- 1976-03-16 ES ES1976219627U patent/ES219627Y/es not_active Expired
Also Published As
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