IL43280A - Preparation of(substituted phenylamidino)urea derivatives pharmaceutical compositions containing them and some new such derivatives - Google Patents

Preparation of(substituted phenylamidino)urea derivatives pharmaceutical compositions containing them and some new such derivatives

Info

Publication number
IL43280A
IL43280A IL43280A IL4328073A IL43280A IL 43280 A IL43280 A IL 43280A IL 43280 A IL43280 A IL 43280A IL 4328073 A IL4328073 A IL 4328073A IL 43280 A IL43280 A IL 43280A
Authority
IL
Israel
Prior art keywords
urea
hydrogen
compound
ami
chloro
Prior art date
Application number
IL43280A
Other languages
English (en)
Other versions
IL43280A0 (en
Inventor
J Diamond
G Douglas
Original Assignee
Rorer Inc William H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer Inc William H filed Critical Rorer Inc William H
Publication of IL43280A0 publication Critical patent/IL43280A0/xx
Publication of IL43280A publication Critical patent/IL43280A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL43280A 1972-09-22 1973-09-21 Preparation of(substituted phenylamidino)urea derivatives pharmaceutical compositions containing them and some new such derivatives IL43280A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29147472A 1972-09-22 1972-09-22

Publications (2)

Publication Number Publication Date
IL43280A0 IL43280A0 (en) 1973-11-28
IL43280A true IL43280A (en) 1977-06-30

Family

ID=23120445

Family Applications (1)

Application Number Title Priority Date Filing Date
IL43280A IL43280A (en) 1972-09-22 1973-09-21 Preparation of(substituted phenylamidino)urea derivatives pharmaceutical compositions containing them and some new such derivatives

Country Status (14)

Country Link
JP (1) JPS593471B2 (fr)
AR (1) AR200024A1 (fr)
BE (1) BE805138A (fr)
CA (1) CA1041908A (fr)
CH (2) CH605703A5 (fr)
DE (1) DE2345951C2 (fr)
ES (1) ES418987A1 (fr)
FR (1) FR2200002B1 (fr)
GB (5) GB1451479A (fr)
IL (1) IL43280A (fr)
NL (1) NL7313040A (fr)
PH (1) PH12016A (fr)
SE (2) SE416952B (fr)
ZA (1) ZA737475B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4488993A (en) * 1972-09-22 1984-12-18 William H. Rorer, Inc. Amidinoureas
US4220658A (en) * 1972-09-22 1980-09-02 William H. Rorer, Inc. Treatment of hypertension with amidinoureas
US4025652A (en) * 1975-03-31 1977-05-24 William H. Rorer, Inc. Amidinoureas
US4326074A (en) 1972-09-22 1982-04-20 William H. Rorer, Inc. Amidinoureas
US4713382A (en) * 1985-05-30 1987-12-15 Syntex (U.S.A.) Inc. N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents
ES2107698T3 (es) * 1993-02-20 1997-12-01 Hoechst Ag Benzoilguanidinas sustituidas, procedimiento para su preparacion, su utilizacion como medicamento, como inhibidores del intercambio celular de na+/h+ o como agente de diagnostico, asi como medicamento que las contiene.

Also Published As

Publication number Publication date
GB1451479A (en) 1976-10-06
SE416953B (sv) 1981-02-16
GB1451478A (en) 1976-10-06
BE805138A (fr) 1974-01-16
FR2200002B1 (fr) 1977-07-15
SE416952B (sv) 1981-02-16
CA1041908A (fr) 1978-11-07
CH605703A5 (fr) 1978-10-13
AU6047973A (en) 1975-03-20
GB1514198A (en) 1978-06-14
PH12016A (en) 1978-10-06
SE7612176L (sv) 1976-11-02
ES418987A1 (es) 1976-07-01
GB1451480A (en) 1976-10-06
FR2200002A1 (fr) 1974-04-19
JPS593471B2 (ja) 1984-01-24
GB1451477A (en) 1976-10-06
DE2345951A1 (de) 1974-04-04
JPS4985046A (fr) 1974-08-15
IL43280A0 (en) 1973-11-28
ZA737475B (en) 1974-10-30
NL7313040A (fr) 1974-03-26
CH614430A5 (en) 1979-11-30
AR200024A1 (es) 1974-10-15
DE2345951C2 (de) 1986-10-23

Similar Documents

Publication Publication Date Title
EP0335832B1 (fr) Arylhydrazones
US3976643A (en) Guanidines
HU208811B (en) Process for producton of biaryl-compounds and pharmaceutical compositions comprising them as medical agent
US3493582A (en) 1-(2,3-epoxypropyl)-5(4)-nitroimidazoles and a process for their preparation
HU223945B1 (hu) 1,2,3,4-Tetrahidro-kinoxalin-dion-származékok és ezeket tartalmazó gyógyszerkészítmények
US3972932A (en) Novel 2,6-disubstituted phenyl-aminoguanidine compounds
US3988345A (en) Imidazoline derivatives and the preparation thereof
HU187478B (en) Process for preparing new imidazolyl-phenyl-amidines and pharmaceutical compositions containing thereof
IL43280A (en) Preparation of(substituted phenylamidino)urea derivatives pharmaceutical compositions containing them and some new such derivatives
US3914306A (en) Guanidines
CZ279340B6 (cs) Hydrazony
Buschauer et al. Synthesis and histamine H2 agonistic activity of arpromidine analogues: replacement of the pheniramine-like moiety by non-heterocyclic groups
US4318915A (en) Substituted guandines and methods of preparation thereof
HU176110B (en) Process for producing thiourea- and guanidine derivatives
US4088785A (en) Amidinoureas for the treatment of cardinascular disorders
US4226867A (en) 3,3-Substituted spiro-1,2,4-benzothiadiazines
US4113868A (en) 5,6-dihydropyrimidin-4(3h)one derivatives, and antiedema compositions and methods employing them
HUT58693A (en) Process for preparation of substances having pharmaceutical effectivity
Ogonor Preparation of N-substituted amidines
PL79192B1 (en) Derivatives of 2-(2&#39;-halo-anilino)1,3-diazacyclo-pentene-(2)[us3462433a]
EP0066799B1 (fr) Dérivés de l&#39;acide nicotinique
US4220658A (en) Treatment of hypertension with amidinoureas
CS244653B2 (en) Production method of new pyridazinel-hydrazone derivatives
IE48442B1 (en) Imidazolylethyl ether derivatives of pyrazolo(3,4-b)pyridine-5-methanols
US4183956A (en) Method for treating gastrointestinal spasms, gastrointestinal hyperacidity and hypertensive disorders with amidinoureas