IL42858A - 2-amino-7,7-diethyl-6-hydroxymethyl-7,8-dihydro-4-pteridinones,their preparation and pharmaceutical compositions containing them - Google Patents
2-amino-7,7-diethyl-6-hydroxymethyl-7,8-dihydro-4-pteridinones,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL42858A IL42858A IL42858A IL4285873A IL42858A IL 42858 A IL42858 A IL 42858A IL 42858 A IL42858 A IL 42858A IL 4285873 A IL4285873 A IL 4285873A IL 42858 A IL42858 A IL 42858A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- formula
- salt
- prepared
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C207/00—Compounds containing nitroso groups bound to a carbon skeleton
- C07C207/04—Compounds containing nitroso groups bound to a carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3581472A GB1454165A (en) | 1972-08-01 | 1972-08-01 | Biologically active compounds and compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
IL42858A0 IL42858A0 (en) | 1973-10-25 |
IL42858A true IL42858A (en) | 1977-02-28 |
Family
ID=10381816
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL42858A IL42858A (en) | 1972-08-01 | 1973-07-31 | 2-amino-7,7-diethyl-6-hydroxymethyl-7,8-dihydro-4-pteridinones,their preparation and pharmaceutical compositions containing them |
Country Status (16)
Country | Link |
---|---|
US (1) | US3963719A (ru) |
JP (1) | JPS4955692A (ru) |
BE (1) | BE803090A (ru) |
CA (1) | CA1019736A (ru) |
CH (1) | CH609985A5 (ru) |
DE (1) | DE2338787A1 (ru) |
DK (1) | DK138019B (ru) |
ES (2) | ES417415A1 (ru) |
FI (1) | FI55662C (ru) |
FR (1) | FR2194438B1 (ru) |
GB (1) | GB1454165A (ru) |
HU (1) | HU171199B (ru) |
IL (1) | IL42858A (ru) |
NL (1) | NL7310579A (ru) |
SE (1) | SE407576B (ru) |
ZA (1) | ZA735210B (ru) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196533A (en) * | 1983-04-11 | 1993-03-23 | South Alabama Medical Science Foundation, Usa | Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3635978A (en) * | 1969-01-28 | 1972-01-18 | Univ Strathclyde | Amino pyrimidines |
GB1363064A (en) * | 1970-07-27 | 1974-08-14 | Wellcome Found | Pyrimidine derivatives as intermediates in the synthesis of pteridines |
BE787236A (fr) * | 1971-08-05 | 1973-02-05 | Wellcome Found | Compositions de potentialisation |
-
1972
- 1972-08-01 GB GB3581472A patent/GB1454165A/en not_active Expired
-
1973
- 1973-07-30 US US05/383,698 patent/US3963719A/en not_active Expired - Lifetime
- 1973-07-31 CA CA177,817A patent/CA1019736A/en not_active Expired
- 1973-07-31 DK DK420173AA patent/DK138019B/da unknown
- 1973-07-31 ES ES417415A patent/ES417415A1/es not_active Expired
- 1973-07-31 DE DE19732338787 patent/DE2338787A1/de not_active Ceased
- 1973-07-31 ZA ZA00735210A patent/ZA735210B/xx unknown
- 1973-07-31 FI FI2401/73A patent/FI55662C/fi active
- 1973-07-31 JP JP48086278A patent/JPS4955692A/ja active Pending
- 1973-07-31 BE BE134128A patent/BE803090A/xx unknown
- 1973-07-31 FR FR7327996A patent/FR2194438B1/fr not_active Expired
- 1973-07-31 IL IL42858A patent/IL42858A/en unknown
- 1973-07-31 CH CH1116173A patent/CH609985A5/xx not_active IP Right Cessation
- 1973-07-31 NL NL7310579A patent/NL7310579A/xx not_active Application Discontinuation
- 1973-07-31 SE SE7310521A patent/SE407576B/xx unknown
- 1973-07-31 HU HU73WE00000493A patent/HU171199B/hu unknown
-
1975
- 1975-11-15 ES ES442673A patent/ES442673A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE803090A (fr) | 1974-01-31 |
DK138019B (da) | 1978-06-26 |
FI55662C (fi) | 1979-09-10 |
AU5873273A (en) | 1975-02-06 |
FI55662B (fi) | 1979-05-31 |
DK138019C (ru) | 1978-11-13 |
ES442673A1 (es) | 1977-04-16 |
JPS4955692A (ru) | 1974-05-30 |
IL42858A0 (en) | 1973-10-25 |
SE407576B (sv) | 1979-04-02 |
ZA735210B (en) | 1975-03-26 |
DE2338787A1 (de) | 1974-02-14 |
CA1019736A (en) | 1977-10-25 |
GB1454165A (en) | 1976-10-27 |
HU171199B (hu) | 1977-11-28 |
ES417415A1 (es) | 1976-06-16 |
NL7310579A (ru) | 1974-02-05 |
CH609985A5 (ru) | 1979-03-30 |
US3963719A (en) | 1976-06-15 |
FR2194438A1 (ru) | 1974-03-01 |
FR2194438B1 (ru) | 1976-07-02 |
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