IL40971A0 - Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them - Google Patents

Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them

Info

Publication number
IL40971A0
IL40971A0 IL40971A IL4097172A IL40971A0 IL 40971 A0 IL40971 A0 IL 40971A0 IL 40971 A IL40971 A IL 40971A IL 4097172 A IL4097172 A IL 4097172A IL 40971 A0 IL40971 A0 IL 40971A0
Authority
IL
Israel
Prior art keywords
derivatives
producing
medicaments containing
substituted pyrimidone
pyrimidone
Prior art date
Application number
IL40971A
Other languages
English (en)
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of IL40971A0 publication Critical patent/IL40971A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL40971A 1971-12-02 1972-11-30 Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them IL40971A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU64387 1971-12-02

Publications (1)

Publication Number Publication Date
IL40971A0 true IL40971A0 (en) 1973-01-30

Family

ID=19726894

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40971A IL40971A0 (en) 1971-12-02 1972-11-30 Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them

Country Status (11)

Country Link
JP (1) JPS4862774A (cs)
BE (1) BE792206A (cs)
DD (1) DD106646A5 (cs)
DE (1) DE2258561A1 (cs)
FR (1) FR2162106A1 (cs)
HU (1) HU164196B (cs)
IL (1) IL40971A0 (cs)
LU (1) LU64387A1 (cs)
NL (1) NL7216309A (cs)
OA (1) OA04289A (cs)
ZA (1) ZA728536B (cs)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
IT1153066B (it) * 1982-11-18 1987-01-14 Mentedison S P A Derivati del pirimidin-4-one ad attivita' erbicida
JPS6172764A (ja) * 1984-09-17 1986-04-14 Hokuriku Seiyaku Co Ltd キナゾリノン誘導体
JPH0696561B2 (ja) * 1985-08-30 1994-11-30 正幸 石川 新規な２−（４−フエニル−１−ピペラジニルアルキル）アミノピリミジン誘導体及びその酸付加塩
DE4425143A1 (de) * 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
HUT76266A (en) * 1995-10-31 1997-07-28 Egyt Gyogyszervegyeszeti Gyar New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components
DE19600934A1 (de) 1996-01-12 1997-07-17 Basf Ag Substituierte Aza- und Diazacycloheptan- und Cyclooctanverbindungen und deren Verwendung
EP1407774A1 (en) * 2002-09-10 2004-04-14 LION Bioscience AG 2-Amino-4-quinazolinones as LXR nuclear receptor binding compounds
CA2518465A1 (en) 2003-03-25 2004-10-14 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
AU2004255581A1 (en) 2003-07-02 2005-01-20 F. Hoffmann-La Roche Ag Arylamine-substituted quinazolinone compounds
DE602004010206T2 (de) 2003-08-13 2008-10-09 Takeda Pharmaceutical Co. Ltd. Dipeptidyl Peptidase Inhibitoren.
EP1911754B1 (en) * 2003-08-13 2013-10-09 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7790734B2 (en) 2003-09-08 2010-09-07 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
UA91002C2 (ru) 2003-11-20 2010-06-25 Янссен Фармацевтика Н.В. 7-фенилалкилзамещенные 2-хинолиноны и 2-хиноксалиноны как ингибиторы поле(адф-рибоза)полимеразы
SG150533A1 (en) 2003-11-20 2009-03-30 Janssen Pharmaceutica Nv 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2- quinoxalinones as poly(adp-ribose) polymerase inhibitors
UA85871C2 (uk) 2004-03-15 2009-03-10 Такеда Фармасьютікал Компані Лімітед Інгібітори дипептидилпептидази
ES2563954T3 (es) 2004-06-30 2016-03-16 Janssen Pharmaceutica Nv Derivados de ftalazina como inhibidores de PARP
NZ551840A (en) * 2004-06-30 2009-07-31 Janssen Pharmaceutica Nv Substituted 2-alkyl quinzolinone derivatives as PARP inhibitors
MXPA06014541A (es) 2004-06-30 2007-03-23 Janssen Pharmaceutica Nv Derivados de quinazolindiona como inhibidores de la poli(adp-ribosa) polimerasa.
FR2877005A1 (fr) * 2004-10-22 2006-04-28 Bioprojet Soc Civ Ile Nouveaux derives d'arylpiperazine
WO2006068978A2 (en) 2004-12-21 2006-06-29 Takeda Pharmaceutial Company Limited Dipeptidyl peptidase inhibitors
JP2008526803A (ja) * 2005-01-07 2008-07-24 ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ Ｃｎｓ障害、痛み、発作、中毒およびてんかんの治療に用いるための置換２‐アミノ‐キナゾリン４‐ｃｎ化合物、その調製、並びに中間生成物としてのその使用
CN101374523B (zh) 2005-09-14 2012-04-11 武田药品工业株式会社 用于治疗糖尿病的二肽基肽酶抑制剂
CA2622642C (en) 2005-09-16 2013-12-31 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
HRP20120346T1 (hr) 2007-03-08 2012-05-31 Janssen Pharmaceutica N.V. Derivati kinolinona kao parp i tank inhibitori
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
JP5525447B2 (ja) 2007-10-26 2014-06-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｐａｒｐ阻害剤としてのキノリノン誘導体
JP5464609B2 (ja) 2008-03-27 2014-04-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ チューブリン重合阻害剤としてのキナゾリノン誘導体
US8889866B2 (en) 2008-03-27 2014-11-18 Janssen Pharmaceutica, Nv Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
CN107226808B (zh) * 2016-03-23 2021-01-01 北京四环制药有限公司 端锚聚合酶抑制剂

Also Published As

Publication number Publication date
NL7216309A (cs) 1973-06-05
DD106646A5 (cs) 1974-06-20
HU164196B (cs) 1974-01-28
JPS4862774A (cs) 1973-09-01
ZA728536B (en) 1973-09-26
OA04289A (fr) 1979-12-31
LU64387A1 (cs) 1973-07-16
DE2258561A1 (de) 1973-06-20
FR2162106A1 (en) 1973-07-13
BE792206A (cs) 1973-06-01

Similar Documents

Publication Publication Date Title
IL40971A0 (en) Substituted pyrimidone-(4) derivatives,a method for producing them and medicaments containing them
HU172686B (hu) Sposob poluchenija 1,1,2,3-tetrakhloro-propena
PH14191A (en) A process of preparing 2,2-methylenediphenols
CA972755A (en) 3,4-dihydro-2h-isoquinoline-1-thiones and process for preparing them
AU458503B2 (en) A CONTAINER ANDA METHOD for producing same
CA983039A (en) 3,4-dihydro-2h-isoquinoline-1-ones and process for preparing them
CA986523A (en) Mesoionic 1,3,4-thiadiazolimino-(5) derivatives and a process for their production
GB1404367A (en) Process for preparing a 1,2-dihydrophthalazine
YU36963B (en) Process for producing hetacillin derivatives
YU314072A (en) Process for obtaining 1,2,3,4,10,10a-hexahydropyridazino (1,2:a)-indol-carboxamides
HK69576A (en) Phenyl-pyridylallylamines, and a process for their preparation
AU4941272A (en) A method for producing 2 substituted adenosine derivatives
AU490537B2 (en) A process for preparing 1, 3 thiazane and 1, 3 thiazine derivatives, andthe compounds so produced
GB1407529A (en) 1,2-dihydroindene-2-spiro-2-piperazine derivatives and process for production thereof
GB1403409A (en) Substituted 3,4-dihydropyrimido-4-5-d- pyridazine derivatives and process for producing them
CA1020947A (en) Substituted 2-hydrazonomethyl-3-hydroxy-4-aza-2,4-pentadienenitriles, a method for producing them and medicaments containing them
IL40022A0 (en) Gona-4,9,11-trien-3-ones and process for preparing them
CA976956A (en) 3-oxo-a-nor-b-homo-oestra-5(10),6-dienes and a process for their manufacture
AU444865B2 (en) A process for preparing 1, 4-benzodiazepines
CA939363A (en) 1,3-benzodioxazole-2-thiones and a process for their production
CA1032956A (en) Substituted 3-chloro-2-hydrazonomethyl-4-aza-2, 4-pentadienenitriles, a method for producing them and medicaments containing them
CA1003859A (en) Process for preparing a new thio-alkylamine and salts thereof
GB1408125A (en) 1,4-diacycloxy-2,3-butanediol and a method for its production
CA869543A (en) Process for preparing 2,3-dihydro-1h-benzodiazepine derivatives and their salts
CA883339A (en) 3,3'-dinitro-octofluorobiphenyl and a process for preparing it