IL40944A - 8beta-pyrimidinoaminomethyl-10alpha-ergoline derivatives - Google Patents
8beta-pyrimidinoaminomethyl-10alpha-ergoline derivativesInfo
- Publication number
- IL40944A IL40944A IL40944A IL4094472A IL40944A IL 40944 A IL40944 A IL 40944A IL 40944 A IL40944 A IL 40944A IL 4094472 A IL4094472 A IL 4094472A IL 40944 A IL40944 A IL 40944A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- pyrimidinoaminomethyl
- 10alpha
- 8beta
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims abstract 6
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 claims abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 3
- 238000006243 chemical reaction Methods 0.000 claims abstract 2
- 238000000034 method Methods 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000005518 carboxamido group Chemical group 0.000 claims 1
- 230000005494 condensation Effects 0.000 claims 1
- 238000009833 condensation Methods 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3193271 | 1971-12-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40944A0 IL40944A0 (en) | 1973-01-30 |
| IL40944A true IL40944A (en) | 1976-04-30 |
Family
ID=11234509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40944A IL40944A (en) | 1971-12-02 | 1972-11-28 | 8beta-pyrimidinoaminomethyl-10alpha-ergoline derivatives |
Country Status (20)
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7416120A (nl) * | 1973-12-21 | 1975-06-24 | Farmaceutici Italia | Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten. |
-
0
- BE BE792188D patent/BE792188A/xx not_active IP Right Cessation
-
1972
- 1972-11-22 NL NL727215817A patent/NL153197B/xx not_active IP Right Cessation
- 1972-11-27 SU SU721851316A patent/SU617014A3/ru active
- 1972-11-27 GB GB5474372A patent/GB1357238A/en not_active Expired
- 1972-11-28 IL IL40944A patent/IL40944A/en unknown
- 1972-11-28 AT AT1011572A patent/AT321478B/de active
- 1972-11-28 NO NO4351/72A patent/NO136643C/no unknown
- 1972-11-28 CA CA157,696A patent/CA975773A/en not_active Expired
- 1972-11-28 IE IE1653/72A patent/IE37429B1/xx unknown
- 1972-11-28 AU AU49351/72A patent/AU465155B2/en not_active Expired
- 1972-11-29 FR FR7242381A patent/FR2162045A1/fr active Granted
- 1972-11-29 ZA ZA728459A patent/ZA728459B/xx unknown
- 1972-11-29 DK DK595972AA patent/DK138689B/da unknown
- 1972-11-29 SE SE7215545A patent/SE385301B/xx unknown
- 1972-11-30 CS CS8190A patent/CS173612B2/cs unknown
- 1972-11-30 JP JP11945772A patent/JPS5634597B2/ja not_active Expired
- 1972-12-01 DE DE2259012A patent/DE2259012C3/de not_active Expired
- 1972-12-01 HU HUFA933A patent/HU165530B/hu unknown
- 1972-12-01 ES ES409189A patent/ES409189A1/es not_active Expired
- 1972-12-01 CH CH1756672A patent/CH590276A5/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1418822A (en) | Imidazo-and pyrimido-2,1-b-quinazolin-2-ones and a process for the preparation thereof | |
| IE41528L (en) | Furfuryl-benzomorphane derivatives. | |
| ES285806A1 (es) | Procedimiento para preparar agentes antiparasitarios | |
| GB1450010A (en) | Preparation of triamino pyrimidine n-oxides | |
| CH612431A5 (en) | Process for the preparation of novel indole derivatives | |
| GB1371022A (en) | Diglycidylbenzimidazolones and a process for their manufacture | |
| GB1467467A (en) | Tricyclic fused imidazole derivatives and a process for the preparation thereof | |
| GB1477302A (en) | Triazolo-isoindole and triazolo-isoquinoline derivatives and their manufacture and uses | |
| IL40944A (en) | 8beta-pyrimidinoaminomethyl-10alpha-ergoline derivatives | |
| GB1418598A (en) | 3-aminocarbazole derivatives and test devices containing them | |
| GB1469006A (en) | 2-phenylhydrazinothiazolines or-thiazines and a process for the preparation thereof | |
| GB1436936A (en) | Erfoline derivatives | |
| GB1337371A (en) | 3-amino-imidazo-1,5-a- pyridines processes for their preparation and pharmaceutical compositions incorporating them | |
| GB1495305A (en) | 3-phenyl-4-oxo-4h-benzopyran derivatives | |
| ES418987A1 (es) | Un procedimiento para la preparacion de nuevos compuestos de fenilamidinourea. | |
| SE7413858L (enrdf_load_stackoverflow) | ||
| IE41382B1 (en) | Benzylamine derivatives process for their production and pharmaceutical compositions containing them | |
| ES419739A1 (es) | Procedimiento para la preparacion de 2-arilamino-imidazoli-nas (2) sustituidas. | |
| GB1388450A (en) | Pyrazolylphenylalkylaminoalkyl-ketones | |
| ES423746A1 (es) | Procedimiento para preparar derivados de 2-aminoindano. | |
| GB1446701A (en) | Vincamine 2-ketoglutarate and process for the production thereof | |
| ES451375A1 (es) | Procedimiento para la preparacion de 2-4 diamino-5-bencil-pirimidinas. | |
| ES401174A1 (es) | Procedimiento para la preparacion de nuevos esteres alcohi-licos del acido tiolcarbamidico basicamente sustituidos. | |
| IL44292A (en) | Preparation of 2-aminoindane derivatives | |
| ES286809A1 (es) | Un procedimiento para la preparacion de compuesto quinazolonicos |