IL38860A - Cyclic esters of phosphoric acid and their use for separating optical,geometric and structural isomers - Google Patents
Cyclic esters of phosphoric acid and their use for separating optical,geometric and structural isomersInfo
- Publication number
- IL38860A IL38860A IL38860A IL3886072A IL38860A IL 38860 A IL38860 A IL 38860A IL 38860 A IL38860 A IL 38860A IL 3886072 A IL3886072 A IL 3886072A IL 38860 A IL38860 A IL 38860A
- Authority
- IL
- Israel
- Prior art keywords
- geometric
- phosphoric acid
- structural isomers
- cyclic esters
- separating optical
- Prior art date
Links
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 title 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 title 1
- 125000004122 cyclic group Chemical group 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Braiding, Manufacturing Of Bobbin-Net Or Lace, And Manufacturing Of Nets By Knotting (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT49167/71A IT951631B (it) | 1971-03-18 | 1971-03-18 | Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi |
Publications (2)
Publication Number | Publication Date |
---|---|
IL38860A0 IL38860A0 (en) | 1972-04-27 |
IL38860A true IL38860A (en) | 1975-06-25 |
Family
ID=11269830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL38860A IL38860A (en) | 1971-03-18 | 1972-02-29 | Cyclic esters of phosphoric acid and their use for separating optical,geometric and structural isomers |
Country Status (18)
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4143028A (en) * | 1977-12-05 | 1979-03-06 | Ciba-Geigy Corporation | Alkylated 1,1'-biphenyl-2,2'-diyl phosphonites and stabilized compositions |
US5288914A (en) * | 1984-08-27 | 1994-02-22 | The Dow Chemical Company | Poly(arylcyclobutenes) |
NL8403224A (nl) * | 1984-10-24 | 1986-05-16 | Oce Andeno Bv | Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen. |
DE3940765A1 (de) * | 1989-12-09 | 1991-06-13 | Hoechst Ag | Verfahren zur herstellung reiner cyclischer phosphorsaeurediarylester |
DE69517810T2 (de) * | 1994-05-16 | 2000-12-14 | Merrell Pharmaceuticals Inc., Cincinnati | Verfahren und diastereomere salze nützlich bei der racemattrennung von racemischer 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-alpha,alpha-dimethylphenyl essigsäure sowie entsprechende diastereomere salze |
DE60008807T2 (de) | 1999-03-24 | 2005-01-13 | Tosoh Corp., Shinnanyo | Binaphtol-monophosphorsäurederivate und deren Verwendung |
JP4725757B2 (ja) * | 1999-03-24 | 2011-07-13 | 東ソー株式会社 | ビナフトールリン酸誘導体及びその利用 |
US6800778B1 (en) | 1999-10-22 | 2004-10-05 | Takeda Chemical Industries, Ltd. | Process for producing optically active naphthalene derivative and optical resolver therefor |
CA2390921A1 (en) * | 1999-11-10 | 2001-05-17 | Hiroyuki Tawada | Process for the production of optically active cyclic enaminone derivative |
US6391926B2 (en) * | 2000-03-13 | 2002-05-21 | Tosoh Corporation | Optically active phosphate derivative |
MXPA04000097A (es) | 2001-07-09 | 2004-05-21 | Zonagen Inc | Metodo y materiales para el tratamiento de deficiencias de testosterona en varones. |
EP1623971A4 (en) * | 2003-04-25 | 2006-11-08 | Toagosei Co Ltd | ASYMMETRIC SYNTHETIC CATALYST BASED ON BRONSTED CHIRAL ACID AND PROCESS FOR ASYMMETRIC SYNTHESIS THEREOF |
US7229557B2 (en) * | 2004-02-04 | 2007-06-12 | Konec, Inc. | Method to separate stereoisomers |
US8420822B2 (en) * | 2009-10-09 | 2013-04-16 | Hetero Research Foundation | Optical resolution of substituted 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles |
UA113291C2 (xx) | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
KR20150041793A (ko) | 2012-08-21 | 2015-04-17 | 레프로스 쎄라피우틱스 아이엔씨. | 트랜스-클로미펜 제형 및 그의 용도 |
US9687458B2 (en) | 2012-11-02 | 2017-06-27 | Repros Therapeutics Inc. | Trans-clomiphene for use in cancer therapy |
CN106068121A (zh) * | 2014-03-11 | 2016-11-02 | 利普生物药剂公司 | 使用单一溶剂进行克罗米芬合成 |
PT3171866T (pt) | 2014-07-24 | 2020-10-21 | Aspen Park Pharmaceuticals Inc | Tratamento dos afrontamentos e perda óssea induzidos pela terapia de privação de androgénios utilizando cis-clomifeno |
EP3015453B1 (en) | 2014-10-28 | 2016-10-12 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Process for the preparation of Clomiphene |
EP3015454A1 (en) | 2014-10-28 | 2016-05-04 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Stable solid form of trans-Clomiphene citrate |
WO2017182097A1 (en) | 2016-04-22 | 2017-10-26 | F.I.S. - Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
IL272924B2 (en) | 2017-09-11 | 2024-01-01 | Atossa Therapeutics Inc | Methods for preparing and using endoxifen |
FR3082842A1 (fr) * | 2018-06-21 | 2019-12-27 | Veru Inc. | Polymorphe de cis-clomiphene (zuclomiphene) et procedes d'utilisation de celui-ci |
MX2022000203A (es) | 2019-07-03 | 2022-03-22 | Atossa Therapeutics Inc | Composiciones de liberacion sostenida de endoxifeno. |
CA3098552A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Processes for the preparation of zuclomiphene and intermediates thereof |
CA3098725A1 (en) | 2019-11-14 | 2021-05-14 | Apotex Inc. | Zuclpomiphene salts and crystalline forms thereof |
CA3105944A1 (en) | 2020-01-22 | 2021-07-22 | Apotex Inc. | Crystalline forms of zuclomiphene citrate |
EP3907213A1 (en) | 2020-05-04 | 2021-11-10 | Pcas | Processes for the production of isomerically pure or enriched cis-clomiphene |
US11578025B2 (en) | 2020-10-19 | 2023-02-14 | Apotex Inc. | Processes for the preparation of zuclomiphene intermediates |
-
1971
- 1971-03-18 IT IT49167/71A patent/IT951631B/it active
-
1972
- 1972-02-28 ZA ZA721297A patent/ZA721297B/xx unknown
- 1972-02-29 IL IL38860A patent/IL38860A/xx unknown
- 1972-03-03 AU AU39611/72A patent/AU462431B2/en not_active Expired
- 1972-03-03 PH PH13312A patent/PH10768A/en unknown
- 1972-03-09 CA CA136,671A patent/CA961500A/en not_active Expired
- 1972-03-09 GB GB1104172A patent/GB1360946A/en not_active Expired
- 1972-03-10 US US00233793A patent/US3848030A/en not_active Expired - Lifetime
- 1972-03-15 SE SE7203303A patent/SE409323B/xx unknown
- 1972-03-16 DE DE2212660A patent/DE2212660C3/de not_active Expired
- 1972-03-17 ES ES400862A patent/ES400862A1/es not_active Expired
- 1972-03-17 FR FR7209350A patent/FR2129741A5/fr not_active Expired
- 1972-03-17 NO NO880/72A patent/NO136357C/no unknown
- 1972-03-17 CH CH395572A patent/CH576921A5/xx not_active IP Right Cessation
- 1972-03-17 JP JP2661472A patent/JPS5547013B1/ja active Pending
- 1972-03-17 BE BE780887A patent/BE780887A/xx unknown
- 1972-03-17 NL NL7203574A patent/NL7203574A/xx not_active Application Discontinuation
- 1972-03-17 DK DK127372AA patent/DK139944B/da unknown
Also Published As
Publication number | Publication date |
---|---|
FR2129741A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-10-27 |
IT951631B (it) | 1973-07-10 |
SE409323B (sv) | 1979-08-13 |
IL38860A0 (en) | 1972-04-27 |
ZA721297B (en) | 1973-03-28 |
DE2212660A1 (de) | 1972-09-28 |
BE780887A (fr) | 1972-07-17 |
DE2212660B2 (de) | 1980-07-10 |
CA961500A (en) | 1975-01-21 |
NO136357B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-05-16 |
US3848030A (en) | 1974-11-12 |
NL7203574A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-09-20 |
PH10768A (en) | 1977-09-05 |
DK139944B (da) | 1979-05-21 |
NO136357C (no) | 1977-08-24 |
DE2212660C3 (de) | 1981-09-24 |
JPS5547013B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1980-11-27 |
AU462431B2 (en) | 1975-06-09 |
ES400862A1 (es) | 1976-04-16 |
DK139944C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1979-10-22 |
GB1360946A (en) | 1974-07-24 |
AU3961172A (en) | 1973-09-06 |
CH576921A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-06-30 |
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