IL38536A - Enzyme composition from venom of snakes and process for the manufacture thereof - Google Patents

Enzyme composition from venom of snakes and process for the manufacture thereof

Info

Publication number
IL38536A
IL38536A IL38536A IL3853672A IL38536A IL 38536 A IL38536 A IL 38536A IL 38536 A IL38536 A IL 38536A IL 3853672 A IL3853672 A IL 3853672A IL 38536 A IL38536 A IL 38536A
Authority
IL
Israel
Prior art keywords
snakes
venom
manufacture
enzyme composition
enzyme
Prior art date
Application number
IL38536A
Other languages
English (en)
Other versions
IL38536A0 (en
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of IL38536A0 publication Critical patent/IL38536A0/xx
Publication of IL38536A publication Critical patent/IL38536A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613Snake venom
    • G01N2333/4636Snake venom from Bothrops sp.
    • G01N2333/464Snake venom from Bothrops sp. from Bothrops atrox; Reptilase; Atroxin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors
    • G01N2333/75Fibrin; Fibrinogen
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • Y10S435/815Enzyme separation or purification by sorption
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/814Enzyme separation or purification
    • Y10S435/816Enzyme separation or purification by solubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL38536A 1971-01-18 1972-01-10 Enzyme composition from venom of snakes and process for the manufacture thereof IL38536A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH73371A CH586233A5 (de) 1971-01-18 1971-01-18

Publications (2)

Publication Number Publication Date
IL38536A0 IL38536A0 (en) 1972-03-28
IL38536A true IL38536A (en) 1975-08-31

Family

ID=4193923

Family Applications (1)

Application Number Title Priority Date Filing Date
IL38536A IL38536A (en) 1971-01-18 1972-01-10 Enzyme composition from venom of snakes and process for the manufacture thereof

Country Status (21)

Country Link
US (1) US3849252A (de)
AR (1) AR196298A1 (de)
AT (1) AT321456B (de)
AU (1) AU476722B2 (de)
BE (1) BE778226A (de)
BR (1) BR7200318D0 (de)
CA (1) CA966418A (de)
CH (1) CH586233A5 (de)
CS (1) CS168578B2 (de)
DE (1) DE2201993C2 (de)
ES (1) ES398962A1 (de)
FI (1) FI51485C (de)
HU (1) HU165725B (de)
IL (1) IL38536A (de)
NL (1) NL176955C (de)
NO (1) NO138145C (de)
PH (1) PH15651A (de)
PL (1) PL82807B1 (de)
SE (1) SE407805B (de)
SU (1) SU581872A3 (de)
ZA (1) ZA72132B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2615844A1 (de) * 1976-04-10 1977-10-20 Knoll Ag Fibrinogen spaltendes enzymsystem
CH626917A5 (de) * 1976-08-17 1981-12-15 Pentapharm Ag
US6613324B1 (en) * 1991-02-28 2003-09-02 Bristol-Myers Squibb Company Adhesive for the gluing of biological tissues
CH681693A5 (de) * 1991-02-28 1993-05-14 Pentapharm Ag
EP0534178B1 (de) * 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Verbesserter Gewebekleber, zubereitet aus Kryopräzipitat
DE4202667C1 (de) * 1992-01-29 1993-05-13 Behringwerke Ag, 3550 Marburg, De
DE4203965A1 (de) * 1992-02-11 1993-08-12 Max Planck Gesellschaft Antidot fuer hirudin und synthetische thrombininhibitoren
CN1091315A (zh) * 1992-10-08 1994-08-31 E·R·斯奎布父子公司 血纤维蛋白封闭剂组合物及其使用方法
EP0691858B1 (de) * 1993-03-30 1999-12-15 Omrix Biopharmaceuticals S.A. Zweikomponenten-fibrinkleber
US5681815A (en) * 1993-06-28 1997-10-28 Sophie Chen Antiviral and antitumor agents
JP3742675B2 (ja) * 1995-06-28 2006-02-08 東菱薬品工業株式会社 虚血−再灌流障害の予防および治療薬
JP3866800B2 (ja) * 1996-08-29 2007-01-10 東菱薬品工業株式会社 アポトーシス関連疾患の予防及び/又は治療薬
US6132598A (en) * 1997-01-08 2000-10-17 Bristol-Myers Squibb Company Centrifuge apparatus with temperature control means
JP2001508447A (ja) * 1997-01-08 2001-06-26 ブリストル−マイヤーズ スクイブ カンパニー 温度制御手段を備えた遠心分離装置
US6365380B2 (en) 2000-02-23 2002-04-02 Pcbu Services, Inc. Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst
CN100335622C (zh) * 2003-03-28 2007-09-05 上海万兴生物制药有限公司 巴曲酶基因的合成及其表达产物的纯化制备
GB2431655A (en) * 2005-10-27 2007-05-02 Pentapharm Ag Antagonisation of anticoagulants
WO2008119203A1 (fr) 2007-03-30 2008-10-09 Shanghai Wanxing Biopharmaceuticals, Co., Ltd. Batroxobine recombinante purifiée à haute activité spécifique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1094301A (en) * 1964-02-21 1967-12-06 Nat Res Dev Improvements relating to anticoagulants
GB1293795A (en) * 1969-07-04 1972-10-25 Twyford Lab Ltd Improvements relating to anticoagulants

Also Published As

Publication number Publication date
SE407805B (sv) 1979-04-23
DE2201993C2 (de) 1986-09-18
AU3793972A (en) 1973-07-19
US3849252A (en) 1974-11-19
HU165725B (de) 1974-10-28
AU476722B2 (en) 1976-09-30
BE778226A (fr) 1972-07-19
BR7200318D0 (pt) 1973-10-04
CS168578B2 (de) 1976-06-29
NL7200638A (de) 1972-07-20
FI51485B (de) 1976-09-30
NO138145C (no) 1978-07-12
DE2201993A1 (de) 1972-08-10
CH586233A5 (de) 1977-03-31
SU581872A3 (ru) 1977-11-25
PL82807B1 (de) 1975-10-31
ZA72132B (en) 1972-09-27
AT321456B (de) 1975-04-10
NO138145B (no) 1978-04-03
CA966418A (en) 1975-04-22
PH15651A (en) 1983-03-11
FI51485C (fi) 1977-01-10
NL176955B (nl) 1985-02-01
IL38536A0 (en) 1972-03-28
ES398962A1 (es) 1976-01-01
AR196298A1 (es) 1973-12-18
NL176955C (nl) 1985-07-01

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