IL36670A - Therapeutic basic copolymers of amino acids - Google Patents

Therapeutic basic copolymers of amino acids

Info

Publication number
IL36670A
IL36670A IL36670A IL3667071A IL36670A IL 36670 A IL36670 A IL 36670A IL 36670 A IL36670 A IL 36670A IL 3667071 A IL3667071 A IL 3667071A IL 36670 A IL36670 A IL 36670A
Authority
IL
Israel
Prior art keywords
therapeutic
amino acids
basic copolymers
copolymers
basic
Prior art date
Application number
IL36670A
Other languages
English (en)
Other versions
IL36670A0 (en
Original Assignee
Sela M
Hirshfeld T
Arnon R
Teitelbaum D
Meshorer A
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sela M, Hirshfeld T, Arnon R, Teitelbaum D, Meshorer A, Yeda Res & Dev filed Critical Sela M
Priority to IL36670A priority Critical patent/IL36670A/xx
Publication of IL36670A0 publication Critical patent/IL36670A0/xx
Priority to GB1420572A priority patent/GB1393435A/en
Priority to US00240244A priority patent/US3849550A/en
Priority to CA139,301A priority patent/CA1006508A/en
Priority to DE2217817A priority patent/DE2217817C2/de
Priority to CH543572A priority patent/CH570167A5/xx
Priority to FR7213911A priority patent/FR2133926B1/fr
Priority to JP4002272A priority patent/JPS5710132B1/ja
Publication of IL36670A publication Critical patent/IL36670A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL36670A 1971-04-21 1971-04-21 Therapeutic basic copolymers of amino acids IL36670A (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IL36670A IL36670A (en) 1971-04-21 1971-04-21 Therapeutic basic copolymers of amino acids
GB1420572A GB1393435A (en) 1971-04-21 1972-03-27 Polyamides
US00240244A US3849550A (en) 1971-04-21 1972-03-31 Therapeutic copolymer
CA139,301A CA1006508A (en) 1971-04-21 1972-04-10 Therapeutic copolymers of amino acids
DE2217817A DE2217817C2 (de) 1971-04-21 1972-04-13 Pharmazeutisches Präparat zur Behandlung von oder zum Schutz gegen autoimmune Erkrankungen, die das Gehirn angreifen
CH543572A CH570167A5 (US06346242-20020212-C00066.png) 1971-04-21 1972-04-13
FR7213911A FR2133926B1 (US06346242-20020212-C00066.png) 1971-04-21 1972-04-20
JP4002272A JPS5710132B1 (US06346242-20020212-C00066.png) 1971-04-21 1972-04-20

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL36670A IL36670A (en) 1971-04-21 1971-04-21 Therapeutic basic copolymers of amino acids

Publications (2)

Publication Number Publication Date
IL36670A0 IL36670A0 (en) 1971-06-23
IL36670A true IL36670A (en) 1974-09-10

Family

ID=11045887

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36670A IL36670A (en) 1971-04-21 1971-04-21 Therapeutic basic copolymers of amino acids

Country Status (8)

Country Link
US (1) US3849550A (US06346242-20020212-C00066.png)
JP (1) JPS5710132B1 (US06346242-20020212-C00066.png)
CA (1) CA1006508A (US06346242-20020212-C00066.png)
CH (1) CH570167A5 (US06346242-20020212-C00066.png)
DE (1) DE2217817C2 (US06346242-20020212-C00066.png)
FR (1) FR2133926B1 (US06346242-20020212-C00066.png)
GB (1) GB1393435A (US06346242-20020212-C00066.png)
IL (1) IL36670A (US06346242-20020212-C00066.png)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494660A (en) * 1985-06-18 1996-02-27 Emory University Method for inhibiting microbial binding to surfaces
US5466445A (en) * 1985-06-18 1995-11-14 Emory University Methods for reducing salmonella in chickens
USRE35862E (en) * 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
US6099856A (en) * 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5693338A (en) * 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5451410A (en) * 1993-04-22 1995-09-19 Emisphere Technologies, Inc. Modified amino acids for encapsulating active agents
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5714167A (en) * 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5811127A (en) * 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US5792451A (en) * 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5643957A (en) * 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5709861A (en) * 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
ES2163444T3 (es) * 1993-04-22 2002-02-01 Emisphere Tech Inc Composiciones y metodos para la administracion oral de farmacos.
US5958457A (en) * 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
AU741590B2 (en) * 1994-05-24 2001-12-06 Yeda Research And Development Co. Ltd. Copolymer-1 improvements in compositions of copolymers
IL113812A (en) * 1994-05-24 2000-06-29 Yeda Res & Dev Copolymer-1 pharmaceutical compositions containing it and its use
AU775214B2 (en) * 1994-05-24 2004-07-22 Yeda Research And Development Co. Ltd. Copolymer-1 improvements in compositions of copolymers
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
BR9604880A (pt) * 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5650386A (en) * 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5989539A (en) * 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6090958A (en) * 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO1997036480A1 (en) 1996-03-29 1997-10-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5965121A (en) * 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) * 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5858964A (en) * 1995-04-14 1999-01-12 Yeda Research And Development Co. Ltd. Pharmaceutical compositions comprising synthetic peptide copolymer for prevention of GVHD
US5820881A (en) * 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US5667806A (en) * 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US5824345A (en) * 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
US6051258A (en) * 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
WO1997010197A1 (en) * 1995-09-11 1997-03-20 Emisphere Technologies, Inc. METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
IL116559A (en) 1995-11-17 2005-11-20 Yissum Res Dev Co Chimeric protein consisting of a bacterial toxin and a myelin basic protein sequence
CA2258264A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US6214791B1 (en) * 1997-01-10 2001-04-10 Yeda Research And Development Co. Ltd. Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1
US5876710A (en) * 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5804688A (en) * 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5939381A (en) * 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5990166A (en) * 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5879681A (en) * 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US6060513A (en) * 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) * 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) * 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
WO2000005249A2 (en) 1998-07-23 2000-02-03 The President And Fellows Of Harvard College Synthetic peptides and methods of use for autoimmune disease therapies
IL141021A0 (en) 1998-07-23 2002-02-10 Yeda Res & Dev Treatment of autoimmune conditions with copolymer 1 and related copolymers
ES2527760T3 (es) * 1998-07-23 2015-01-29 Yeda Research And Development Co., Ltd. Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
US6800287B2 (en) * 1998-09-25 2004-10-05 Yeda Research And Development Co., Ltd. Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7083777B1 (en) * 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6531130B1 (en) 1999-07-06 2003-03-11 The Board Of Trustees Of The Leland Stanford University Treatment of demyelinating autoimmune disease with ordered peptides
KR100822695B1 (ko) * 2000-01-20 2008-04-17 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 코폴리머 1 및 관련된 펩티드들 및 폴리펩티드 및 이들로처치된 티세포들의 신경보호 요법을 위한 사용
ZA200206457B (en) * 2000-02-18 2003-08-13 Yeda Res & Dev Oral, nasal and pulmonary dosage formulations of copolymer 1.
US20020077278A1 (en) * 2000-06-05 2002-06-20 Yong V. Wee Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
US20020037848A1 (en) * 2000-06-07 2002-03-28 Michal Eisenbach-Schwartz Use of copolymer 1 and related peptides and polypeptides and T cells treated therewith for neuroprotective therapy
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
WO2001097785A2 (en) * 2000-06-20 2001-12-27 Caprion Pharmaceuticals Inc. Basic copolymers for the treatment of prion-related-disease
IL137460A0 (en) 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
DE60237170D1 (de) * 2001-12-04 2010-09-09 Teva Pharma Verfahren zur messung der wirkstärke von glatirameracetat
ES2322566T3 (es) * 2001-12-06 2009-06-23 Yeda Research And Development Co., Ltd. Vacuna y uso de la misma para el tratamiento de la esclerosis lateral amiotrofica.
EP1565486A2 (en) * 2002-11-13 2005-08-24 Apotex Pharmachem Inc. Process for the preparation of glatiramer acetate by polymerisation of n-carboxy anhydrides of l-alanine, l-tyrosine, benzyl l-glutamate and benzyloxycarbonyl l-lysine
WO2004091573A1 (en) * 2003-03-04 2004-10-28 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and alphacalcidol for the treatment of multiple sclerosis
EP1638581A2 (en) * 2003-03-31 2006-03-29 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
WO2005041933A1 (en) * 2003-10-31 2005-05-12 Teva Pharmaceutical Industries, Ltd. Nanoparticles for drug delivery
EP2301569B1 (en) 2003-11-12 2018-05-02 Yeda Research and Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
JP2007527873A (ja) * 2004-03-01 2007-10-04 ペプチミューン，インコーポレイテッド 自己免疫疾患の治療のための方法および組成物
US20050260770A1 (en) * 2004-04-01 2005-11-24 Cohen Irun R Antigen array and diagnostic uses thereof
US7655221B2 (en) * 2004-05-07 2010-02-02 Peptimmune, Inc. Methods of treating disease with random copolymers
WO2005112972A1 (en) 2004-05-07 2005-12-01 Peptimmune, Inc. Methods of treating disease with random copolymers
US20060194725A1 (en) * 2004-05-07 2006-08-31 James Rasmussen Methods of treating disease with random copolymers
WO2005112911A2 (en) * 2004-05-21 2005-12-01 The Regents Of The University Of California Compositions and methods for treating myelin deficiency disorders
SG153871A1 (en) 2004-06-25 2009-07-29 Id Biomedical Corp Quebec Compositions and methods for treating neurological disorders
ZA200702591B (en) * 2004-09-09 2009-03-25 Teva Pharma Process for preparation of mixtures of polypeptides using purified hydrobromic acid
PL1797109T3 (pl) * 2004-09-09 2016-11-30 Mieszaniny polipeptydów, kompozycje zawierające je i procesy ich wytwarzania oraz ich zastosowania
WO2006050122A1 (en) * 2004-10-29 2006-05-11 Sandoz Ag Processes for preparing glatiramer
US20060172942A1 (en) * 2005-02-02 2006-08-03 Teva Pharmaceutical Industries, Ltd. Process for producing polypeptide mixtures using hydrogenolysis
WO2007022193A2 (en) * 2005-08-15 2007-02-22 Wai Hong Chan Process for the preparation of copolymer-1
WO2007092451A2 (en) 2006-02-06 2007-08-16 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
US8470603B2 (en) 2006-04-28 2013-06-25 Momenta Pharmaceuticals, Inc. Methods of evaluating diethylamide in glatiramer acetate
KR100831796B1 (ko) * 2006-05-29 2008-05-28 엘지전자 주식회사 타임 쉬프트 기능을 내장한 영상표시기기 및 그 재생 방법
AU2007264682B2 (en) 2006-06-28 2012-09-06 Yeda Research & Development Co. Ltd Method of treatment of age-related macular degeneration
US20100183658A1 (en) * 2007-03-30 2010-07-22 The Brigham And Women's Hospital, Inc. Novel Compounds for Enhancing MHC Class II Therapies
AU2008265692A1 (en) * 2007-06-21 2008-12-24 Momenta Pharmaceuticals, Inc. Copolymer assay
CA2705046C (en) * 2007-07-31 2015-03-03 Natco Pharma Limited Process for the preparation glatiramer acetate (copolymer-1)
WO2009017775A2 (en) * 2007-08-02 2009-02-05 Scinopharm Taiwan Ltd. Process for the preparation of a polypeptide
US8193147B2 (en) 2007-09-24 2012-06-05 Hadasit Medical Research Services & Development Ltd. Use of copolymer 1 for treatment of muscular dystrophy
ES2449865T5 (es) * 2008-04-16 2022-11-18 Momenta Pharmaceuticals Inc Análisis de composiciones de copolímeros de aminoácidos
AU2009279636A1 (en) * 2008-08-07 2010-02-11 Scinopharm Taiwan, Ltd. Synthesis of glatiramer acetate
AR074881A1 (es) * 2008-12-24 2011-02-16 Synthon Bv Un proceso para purificar una mezcla de polimeros
EP2414384B2 (en) 2009-04-03 2023-05-03 Momenta Pharmaceuticals, Inc. Control of copolymer compositions
US9150609B2 (en) 2009-06-04 2015-10-06 Council Of Scientific & Industrial Research Process for the preparation of copolymer-1 using a polymer supported dialkylamine initiator
US8691790B2 (en) * 2009-07-27 2014-04-08 James Layne Boucher Therapy of neurological inflammatory diseases with (5'-deoxy-5'-adenosyl) cobamamide, recombinant human growth hormone, interleukins IL-1, IL-6, IL-11, epidermal growth factor, and physiotherapy
EA032283B1 (ru) 2009-08-20 2019-05-31 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Терапия глатирамером ацетатом с низкой кратностью
US8377885B2 (en) 2010-01-04 2013-02-19 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
EP2398488B1 (en) 2010-01-04 2018-11-14 Mapi Pharma Limited Depot system comprising glatiramer acetate
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
EP2523668A1 (en) 2010-01-13 2012-11-21 Ramot at Tel-Aviv University Ltd Treatment of multiple sclerosis
JP2013541010A (ja) 2010-10-11 2013-11-07 テバ ファーマシューティカル インダストリーズ リミティド グラチラマーアセテートに対する臨床的な反応の予測可能なバイオマーカーとしてのサイトカインバイオマーカー
WO2012054518A1 (en) * 2010-10-18 2012-04-26 Lanco Biosciences, Inc. Delivery of copolymers by microinjection systems
RU2604521C2 (ru) 2011-02-14 2016-12-10 Юсв Прайвит Лимитед Сополимер-1, способы его получения и аналитические методы
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
US20140348861A1 (en) 2011-05-05 2014-11-27 National Institute Of Immunology Synthetic peptides and random copolymers for the treatment of autoimmune disorders
WO2013009885A2 (en) 2011-07-11 2013-01-17 Momenta Pharmaceuticals, Inc. Evaluation of copolymer diethylamide
WO2013009864A1 (en) 2011-07-11 2013-01-17 Momenta Pharmaceuticals, Inc. Structure assessment of heterogeneous polypeptide mixtures
EP2731617A4 (en) 2011-07-12 2015-07-01 Brigham & Womens Hospital LIPID-CONTAINING PSA COMPOSITIONS, METHODS OF ISOLATION AND METHODS OF USING SAME
US8575198B1 (en) 2011-09-07 2013-11-05 Momenta Pharmaceuticals, Inc. In-process control for the manufacture of glatiramer acetate
BR112014008752A2 (pt) 2011-10-10 2017-04-25 Teva Pharma polimorfismos de nucleotídeos singulares úteis para predizer a resposta clínica para acetato de glatirâmero
WO2013139728A1 (en) 2012-03-19 2013-09-26 Synthon Bv Glatiramer acetate human monocyte cell-based potency assay
EP2642290A1 (en) 2012-03-19 2013-09-25 Synthon BV Glatiramer acetate human monocytic cell line-based potency assay
CA2884267A1 (en) 2012-10-10 2014-04-17 Teva Pharmaceutical Industries Ltd. Biomarkers predictive for clinical response for glatiramer acetate
WO2014060942A2 (en) * 2012-10-20 2014-04-24 Mahesh Kandula Compositions and methods of for the treatment of multiple sclerosis and neurodegenerative diseases
ES2527577T3 (es) 2013-03-08 2015-01-27 Teva Pharmaceutical Industries, Ltd. Aparato inyector reutilizable para jeringa
RS53779B1 (en) 2013-03-08 2015-06-30 Teva Pharmaceutical Industries Ltd. Injectable Reusable Injection Device
AU2014244550B2 (en) 2013-03-14 2018-11-01 Mylan Inc. Glatiramer acetate response biomarker mRNA potency assay
WO2014173463A1 (en) 2013-04-26 2014-10-30 Synthon Bv Glatiramer acetate human monocytic cell line-based potency assay
CN103265624B (zh) * 2013-05-27 2015-04-22 成都圣诺生物制药有限公司 格拉替雷的制备方法
UY35790A (es) 2013-10-21 2015-05-29 Teva Pharma Marcadores genéticos que predicen la respuesta al acetato de glatiramer
CN105917001B (zh) 2013-10-24 2020-11-20 迈兰公司 用于评估醋酸格拉替雷制品的免疫学同一性的人类t细胞系试验
JP2017503169A (ja) 2013-12-31 2017-01-26 イエダ・リサーチ・アンド・デベロツプメント・カンパニー・リミテツド オリゴヌクレオチド抗原を使用する全身性エリテマトーデスの診断
CA3129892A1 (en) 2014-03-12 2015-09-17 Yeda Research And Development Co. Ltd. Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
DK3185882T3 (da) 2014-08-29 2020-01-27 Region Midtjylland Positivt ladede copolymerer til anvendelse som antimikrobielle midler
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
CN107533058A (zh) 2015-03-01 2018-01-02 免疫阵列有限公司 使用蛋白、肽和寡核苷酸抗原诊断系统性红斑狼疮
US10857177B2 (en) 2015-08-19 2020-12-08 President And Fellows Of Harvard College Lipidated PSA compositions and methods
EP3147667B1 (en) 2015-09-24 2019-06-12 CHEMI S.p.A. Analysis of the molecular weight distribution of complex polypeptide mixtures
EP3170836B1 (en) 2015-11-23 2018-10-24 Chemi SPA Rp-hplc analysis of complex polypeptide mixtures
WO2018002930A1 (en) 2016-06-30 2018-01-04 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
EP3484441A4 (en) 2016-07-15 2020-03-18 President and Fellows of Harvard College GLYCOLIPID COMPOSITIONS AND METHODS OF USE
BR112019017724A2 (pt) 2017-03-26 2020-03-31 Mapi Pharma Ltd. Sistemas depot de glatiramer para tratar formas progressivas de esclerose múltipla
WO2018211498A1 (en) 2017-05-15 2018-11-22 Stem Cell Medicine Ltd. Treatment of multiple sclerosis with adipose-derived stem cells
EP3624815A4 (en) 2017-05-15 2021-01-20 Stem Cell Medicine Ltd. TREATMENT OF MULTIPLE SCLEROSIS WITH LONG-ACTING GLATIRAMER AND ADAPTIVE STEM CELLS
WO2019175869A1 (en) 2018-03-12 2019-09-19 Yeda Research And Development Co. Ltd Treatment of a heart disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB822192A (en) * 1956-08-29 1959-10-21 Ilford Ltd Improvements in or relating to the production of photographic emulsions

Also Published As

Publication number Publication date
FR2133926A1 (US06346242-20020212-C00066.png) 1972-12-01
DE2217817A1 (US06346242-20020212-C00066.png) 1972-11-16
CA1006508A (en) 1977-03-08
DE2217817C2 (de) 1983-05-05
IL36670A0 (en) 1971-06-23
FR2133926B1 (US06346242-20020212-C00066.png) 1975-12-26
GB1393435A (en) 1975-05-07
JPS5710132B1 (US06346242-20020212-C00066.png) 1982-02-25
CH570167A5 (US06346242-20020212-C00066.png) 1975-12-15
US3849550A (en) 1974-11-19

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