IL36163A - 1-) 2,2,2-Trifluoroethyl (-2,3-dihydro-5-phenyl-H1-1,4-benzoriazepines and processes for their preparation - Google Patents

1-) 2,2,2-Trifluoroethyl (-2,3-dihydro-5-phenyl-H1-1,4-benzoriazepines and processes for their preparation

Info

Publication number
IL36163A
IL36163A IL36163A IL3616371A IL36163A IL 36163 A IL36163 A IL 36163A IL 36163 A IL36163 A IL 36163A IL 3616371 A IL3616371 A IL 3616371A IL 36163 A IL36163 A IL 36163A
Authority
IL
Israel
Prior art keywords
compound
process according
formula
general formula
oxide
Prior art date
Application number
IL36163A
Other languages
English (en)
Hebrew (he)
Other versions
IL36163A0 (en
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of IL36163A0 publication Critical patent/IL36163A0/xx
Publication of IL36163A publication Critical patent/IL36163A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL36163A 1970-02-13 1971-02-09 1-) 2,2,2-Trifluoroethyl (-2,3-dihydro-5-phenyl-H1-1,4-benzoriazepines and processes for their preparation IL36163A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1133670A 1970-02-13 1970-02-13

Publications (2)

Publication Number Publication Date
IL36163A0 IL36163A0 (en) 1971-04-28
IL36163A true IL36163A (en) 1976-09-30

Family

ID=21749938

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36163A IL36163A (en) 1970-02-13 1971-02-09 1-) 2,2,2-Trifluoroethyl (-2,3-dihydro-5-phenyl-H1-1,4-benzoriazepines and processes for their preparation

Country Status (22)

Country Link
US (1) US3723414A (fr)
AT (1) AT305286B (fr)
BE (1) BE762758A (fr)
CA (1) CA967152A (fr)
CH (1) CH581636A5 (fr)
CY (1) CY835A (fr)
DE (2) DE2115906A1 (fr)
ES (1) ES388129A1 (fr)
FI (1) FI52978C (fr)
FR (1) FR2081510B1 (fr)
GB (1) GB1297206A (fr)
HK (1) HK13576A (fr)
IE (1) IE35306B1 (fr)
IL (1) IL36163A (fr)
KE (1) KE2597A (fr)
MY (1) MY7600086A (fr)
NL (1) NL7101705A (fr)
NO (1) NO132799C (fr)
PL (1) PL88933B1 (fr)
SE (1) SE384858B (fr)
SU (1) SU437295A3 (fr)
ZA (1) ZA71812B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221558C2 (de) 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3131178A (en) * 1964-04-28 Process for producing s-phenyl-l
US3501460A (en) * 1966-06-03 1970-03-17 Hoffmann La Roche Dehydration process for forming benzodiazepines
US3429874A (en) * 1966-12-22 1969-02-25 Schering Corp 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation
US3546212A (en) * 1968-06-12 1970-12-08 Hoffmann La Roche Oxidation of benzodiazepines with ruthenium tetroxide
FR2024239B1 (fr) * 1968-11-26 1973-01-12 Scherico Ltd

Also Published As

Publication number Publication date
CY835A (en) 1976-09-10
IL36163A0 (en) 1971-04-28
FR2081510A1 (fr) 1971-12-03
GB1297206A (fr) 1972-11-22
NO132799B (fr) 1975-09-29
PL88933B1 (fr) 1976-10-30
FI52978B (fr) 1977-09-30
MY7600086A (en) 1976-12-31
CH581636A5 (fr) 1976-11-15
DE2106175A1 (de) 1971-09-30
IE35306L (en) 1971-08-13
ZA71812B (en) 1971-10-27
US3723414A (en) 1973-03-27
DE2115906A1 (de) 1971-10-21
HK13576A (en) 1976-03-19
NL7101705A (fr) 1971-08-17
KE2597A (en) 1976-02-27
AT305286B (de) 1973-02-26
CA967152A (en) 1975-05-06
ES388129A1 (es) 1973-05-01
IE35306B1 (en) 1976-01-07
FR2081510B1 (fr) 1974-09-27
FI52978C (fr) 1978-01-10
BE762758A (fr) 1971-08-10
NO132799C (fr) 1976-01-07
SU437295A3 (ru) 1974-07-25
SE384858B (sv) 1976-05-24

Similar Documents

Publication Publication Date Title
CA1184175A (fr) Imidazodiazepines
CS251795B2 (en) Method of 5h-2,3-benzodiazepine's derivatives preparation
GB2093842A (en) Imidazodiazepines
IL36163A (en) 1-) 2,2,2-Trifluoroethyl (-2,3-dihydro-5-phenyl-H1-1,4-benzoriazepines and processes for their preparation
US3711470A (en) 5-phenyl-7-bromo-1h-1,5-benzodiazepine-2,4-(3h,5h)-diones
US3703525A (en) Triazolo(1,5-a)(1,4)benzodiazepine derivatives
DE2539114A1 (de) 7-substituierte 3-(aminomethyl)- 3,5-dihydro-as-triazino eckige klammer auf 4,3-a eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-2-(1h)-one und ein verfahren zu deren herstellung
US3757008A (en) Sses for preparing same 1 - (carboxyl-heteroalkyl) - 1,4-benzodiazepine derivatives and proce
US4587245A (en) Method of treating neuropsychic disturbances by benzodiazepine derivatives and composition therefor
US3903103A (en) 4-Amino-s-triazolo-{8 4,3-a{9 {8 1,4{9 benzodiazepine
US3850932A (en) 5-(2-carboxy and 2-carboalkoxy-phenylamino)-1,2,4-triazolo-quinazolines
US3894025A (en) 1-Piperazino-6-phenyl-4H-s-triazolo{8 4,3-a{9 {8 1,4{9 -benzodiazepine compounds
US3686308A (en) 5-lower alkanoyl-2-glycylamino-benzophenones
US3808318A (en) 1,2,3-benzotriazin-4(3h)-ones
JPH05503082A (ja) イミダゾキノキサリン化合物、その製造及び使用
US4338314A (en) [1,2]Anellated-7-phenyl-1,4-benzodiazepine and pharmaceutical compositions thereof and use for treatment of ulcers
US3247186A (en) Certain 2-lower alkoxy-5-phenyl-3h-1, 4-benzodiazepine 4-oxide compounds and their preparation
US3714178A (en) 6,7-DIHYDRO-7-ALKYL-5H-1,2,4-TRIAZOLO[4,3-d][1,4]BENZODIAZEPINES AND THEIR PRODUCTION
US3651143A (en) Amino and substituted amino containing benzocycloheptenones
US3891643A (en) Pyrrolo{8 1,2,3-de{9 quinoxalin-2-(3H)-ones and related compounds
US4239684A (en) 1,5'-Benzodiazepine-2-ones, pharmaceutical compositions thereof and method of use thereof
US3946032A (en) Acetal derivatives of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carboxaldehyde
USRE28315E (en) Cooc.hi
US4694003A (en) Method of treating depression with 5-(aminoalkyl)-11-phenyl-5H-dibenzo(b,e)(1,4) diazepines
US3755360A (en) 2,3,4,5-tetrahydro-7h-(1,3)diazepino-(2,1-a)isoindoles