ES388129A1 - Procedimiento para la preparacion de nuevos compuestos de benzodiazepina. - Google Patents

Procedimiento para la preparacion de nuevos compuestos de benzodiazepina.

Info

Publication number
ES388129A1
ES388129A1 ES388129A ES388129A ES388129A1 ES 388129 A1 ES388129 A1 ES 388129A1 ES 388129 A ES388129 A ES 388129A ES 388129 A ES388129 A ES 388129A ES 388129 A1 ES388129 A1 ES 388129A1
Authority
ES
Spain
Prior art keywords
benzodiazepines
polyfluoroalkyl
dihydro
intermediates
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES388129A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of ES388129A1 publication Critical patent/ES388129A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES388129A 1970-02-13 1971-02-10 Procedimiento para la preparacion de nuevos compuestos de benzodiazepina. Expired ES388129A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1133670A 1970-02-13 1970-02-13

Publications (1)

Publication Number Publication Date
ES388129A1 true ES388129A1 (es) 1973-05-01

Family

ID=21749938

Family Applications (1)

Application Number Title Priority Date Filing Date
ES388129A Expired ES388129A1 (es) 1970-02-13 1971-02-10 Procedimiento para la preparacion de nuevos compuestos de benzodiazepina.

Country Status (22)

Country Link
US (1) US3723414A (es)
AT (1) AT305286B (es)
BE (1) BE762758A (es)
CA (1) CA967152A (es)
CH (1) CH581636A5 (es)
CY (1) CY835A (es)
DE (2) DE2115906A1 (es)
ES (1) ES388129A1 (es)
FI (1) FI52978C (es)
FR (1) FR2081510B1 (es)
GB (1) GB1297206A (es)
HK (1) HK13576A (es)
IE (1) IE35306B1 (es)
IL (1) IL36163A (es)
KE (1) KE2597A (es)
MY (1) MY7600086A (es)
NL (1) NL7101705A (es)
NO (1) NO132799C (es)
PL (1) PL88933B1 (es)
SE (1) SE384858B (es)
SU (1) SU437295A3 (es)
ZA (1) ZA71812B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2221558C2 (de) 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
AU678503B2 (en) * 1993-09-24 1997-05-29 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds and their use as squalene synthetase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3131178A (en) * 1964-04-28 Process for producing s-phenyl-l
US3501460A (en) * 1966-06-03 1970-03-17 Hoffmann La Roche Dehydration process for forming benzodiazepines
US3429874A (en) * 1966-12-22 1969-02-25 Schering Corp 1-polyhalogenoalkyl-2-oxo-1,3-dihydro-2h-1,4-benzodiazepines
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation
US3546212A (en) * 1968-06-12 1970-12-08 Hoffmann La Roche Oxidation of benzodiazepines with ruthenium tetroxide
FR2024239B1 (es) * 1968-11-26 1973-01-12 Scherico Ltd

Also Published As

Publication number Publication date
BE762758A (fr) 1971-08-10
DE2115906A1 (de) 1971-10-21
PL88933B1 (es) 1976-10-30
NO132799C (es) 1976-01-07
DE2106175A1 (de) 1971-09-30
SU437295A3 (ru) 1974-07-25
FR2081510B1 (es) 1974-09-27
IL36163A (en) 1976-09-30
MY7600086A (en) 1976-12-31
FI52978C (es) 1978-01-10
FI52978B (es) 1977-09-30
SE384858B (sv) 1976-05-24
US3723414A (en) 1973-03-27
CA967152A (en) 1975-05-06
IE35306B1 (en) 1976-01-07
NL7101705A (es) 1971-08-17
IE35306L (en) 1971-08-13
FR2081510A1 (es) 1971-12-03
NO132799B (es) 1975-09-29
KE2597A (en) 1976-02-27
ZA71812B (en) 1971-10-27
CY835A (en) 1976-09-10
GB1297206A (es) 1972-11-22
AT305286B (de) 1973-02-26
IL36163A0 (en) 1971-04-28
HK13576A (en) 1976-03-19
CH581636A5 (es) 1976-11-15

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