IL34632A - N-oxides of benzyl-pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

N-oxides of benzyl-pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL34632A
IL34632A IL34632A IL3463270A IL34632A IL 34632 A IL34632 A IL 34632A IL 34632 A IL34632 A IL 34632A IL 3463270 A IL3463270 A IL 3463270A IL 34632 A IL34632 A IL 34632A
Authority
IL
Israel
Prior art keywords
pyrimidines
benzyl
oxides
preparation
pharmaceutical compositions
Prior art date
Application number
IL34632A
Other languages
English (en)
Other versions
IL34632A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL34632A0 publication Critical patent/IL34632A0/xx
Publication of IL34632A publication Critical patent/IL34632A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
IL34632A 1969-06-12 1970-06-01 N-oxides of benzyl-pyrimidines,their preparation and pharmaceutical compositions containing them IL34632A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH897069A CH513181A (de) 1969-06-12 1969-06-12 Verfahren zur Herstellung von N-Oxyden von Benzylpyrimidinen

Publications (2)

Publication Number Publication Date
IL34632A0 IL34632A0 (en) 1970-08-19
IL34632A true IL34632A (en) 1973-08-29

Family

ID=4346865

Family Applications (1)

Application Number Title Priority Date Filing Date
IL34632A IL34632A (en) 1969-06-12 1970-06-01 N-oxides of benzyl-pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (1) US3715357A (de)
AT (1) AT294843B (de)
BE (1) BE751790A (de)
BR (1) BR6915095D0 (de)
CA (1) CA955944A (de)
CH (1) CH513181A (de)
DE (1) DE2026997A1 (de)
DK (1) DK124682B (de)
ES (1) ES380642A1 (de)
FR (1) FR2052954B1 (de)
GB (1) GB1256849A (de)
IE (1) IE34683B1 (de)
IL (1) IL34632A (de)
NL (1) NL7008610A (de)
NO (1) NO127237B (de)
SE (1) SE367412B (de)
YU (1) YU33390B (de)
ZA (1) ZA703569B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993761A (en) * 1971-12-01 1976-11-23 Hoffmann-La Roche Inc. Antibacterial compositions
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
AR204082A1 (es) * 1972-06-26 1975-11-20 Hoffmann La Roche Procedimiento para preparar derivados de n-oxidos de 2,4-diamino-5-(3-metoxi-4,5-metilendioxibencil)pirimidina
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
CH591457A5 (de) * 1973-11-08 1977-09-15 Hoffmann La Roche
US4076810A (en) * 1973-11-08 1978-02-28 Hoffmann-La Roche Inc. Benzylpyrimidine antibacterial composition
AU2002350212A1 (en) * 2001-11-20 2003-06-10 Dana Farber Cancer Institute Pharmaceutically active compounds and methods of use thereof
BRPI0508461B8 (pt) * 2004-03-05 2021-05-25 Hoffmann La Roche diaminopirimidinas, seus usos, e composição farmacêutica
JP4850911B2 (ja) * 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３およびｐ２ｘ２／３モジュレーターとしてのジアミノピリミジン
JP4850913B2 (ja) * 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３及びｐ２ｘ２／３調節因子としてのジアミノピリジン
ES2601178T3 (es) * 2005-09-01 2017-02-14 F. Hoffmann-La Roche Ag Diaminopirimidinas como moduladores de P2X3 y P3X2/3

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2518130A (en) * 1945-04-26 1950-08-08 Evans N-oxides of tertiary amines and process of preparing same
US2500131A (en) * 1945-06-27 1950-03-07 Ralph L Evans Di-nu-oxides of amino-substituted acridines and quinolines
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
FR1453056A (fr) * 1964-11-12 1966-04-15 Hoffmann La Roche Procédé pour la préparation de dérivés de pyrimidine
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
US3382248A (en) * 1965-11-01 1968-05-07 Upjohn Co 6-amino-4, 5-di(substituted amino)-1, 2-dihydro-1-hydroxy-2-iminopyrimidines
US3464987A (en) * 1966-02-21 1969-09-02 Upjohn Co 1,2-dihydro-1-hydroxy-2-imino-6-(lower alkyl)pyrimidines

Also Published As

Publication number Publication date
IE34683B1 (en) 1975-07-23
SE367412B (de) 1974-05-27
BR6915095D0 (pt) 1973-03-08
CH513181A (de) 1971-09-30
ZA703569B (en) 1971-01-27
AT294843B (de) 1971-12-10
IE34683L (en) 1970-12-12
ES380642A1 (es) 1972-10-16
US3715357A (en) 1973-02-06
GB1256849A (de) 1971-12-15
FR2052954A1 (de) 1971-04-16
YU33390B (en) 1976-12-31
FR2052954B1 (de) 1973-08-10
IL34632A0 (en) 1970-08-19
BE751790A (fr) 1970-12-11
DK124682B (da) 1972-11-13
NO127237B (de) 1973-05-28
YU132870A (en) 1976-06-30
CA955944A (en) 1974-10-08
DE2026997A1 (de) 1970-12-23
NL7008610A (de) 1970-12-15

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