IL33949A - 5,6-dehydro pge2,pgf2alpha and pgf2beta derivatives - Google Patents
5,6-dehydro pge2,pgf2alpha and pgf2beta derivativesInfo
- Publication number
- IL33949A IL33949A IL33949A IL3394970A IL33949A IL 33949 A IL33949 A IL 33949A IL 33949 A IL33949 A IL 33949A IL 3394970 A IL3394970 A IL 3394970A IL 33949 A IL33949 A IL 33949A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- pgf2beta
- pgf2alpha
- pge2
- dehydro
- Prior art date
Links
- 150000003166 prostaglandin E2 derivatives Chemical class 0.000 title 1
- 150000003169 prostaglandin F2α derivatives Chemical class 0.000 title 1
- 150000003170 prostaglandin F2β derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000004494 ethyl ester group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 235000002639 sodium chloride Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80740569A | 1969-03-14 | 1969-03-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL33949A0 IL33949A0 (en) | 1970-05-21 |
IL33949A true IL33949A (en) | 1976-06-30 |
Family
ID=25196294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL33949A IL33949A (en) | 1969-03-14 | 1970-02-23 | 5,6-dehydro pge2,pgf2alpha and pgf2beta derivatives |
Country Status (10)
Country | Link |
---|---|
BE (1) | BE747348A (fr) |
BR (1) | BR6915068D0 (fr) |
CA (1) | CA968348A (fr) |
CH (3) | CH549549A (fr) |
DE (1) | DE2011969A1 (fr) |
ES (1) | ES377342A1 (fr) |
FR (1) | FR2034951B1 (fr) |
GB (2) | GB1282661A (fr) |
IL (1) | IL33949A (fr) |
NL (1) | NL7003298A (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4008263A (en) * | 1969-03-14 | 1977-02-15 | The Upjohn Company | Racemic fluoro-substituted PGF2 .sub.α analogs |
US3993687A (en) * | 1969-03-14 | 1976-11-23 | The Upjohn Company | Racemic fluoro-substituted PGB2 analogs |
US3983153A (en) * | 1969-03-14 | 1976-09-28 | The Upjohn Company | Racemic fluoro-substituted PGE2 analogs |
US3940438A (en) * | 1971-05-24 | 1976-02-24 | Alza Corporation | Crystalline racemic 9α,11α,15(S)-trihydroxy-5-cis,13-trans-prostadienoic acid |
US3988361A (en) * | 1971-11-16 | 1976-10-26 | The Upjohn Company | 8β-PGE2 and related compounds |
GB1396206A (en) * | 1972-04-27 | 1975-06-04 | Upjohn Co | Prostaglandins and the preparation thereof |
US4056555A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGA2 analogs |
US4056556A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGE2 analogs |
US4001300A (en) * | 1975-02-24 | 1977-01-04 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGF2 analogs |
US4059614A (en) * | 1975-02-24 | 1977-11-22 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGE1 analogs |
US4056557A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGF1 analogs |
US4056554A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-13,14-dihydro-PGF1, analogs |
US4053502A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGE1 analogs |
US4013695A (en) * | 1975-10-02 | 1977-03-22 | The Upjohn Company | 4,4,5,5-Tetradehydro-PGE1 analogs |
US4053500A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGF1α analogs |
US5990168A (en) * | 1996-04-18 | 1999-11-23 | Alberta Cancer Board | Methods and compositions for the treatment of ataxia telangiectasia |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3069322A (en) * | 1958-05-28 | 1962-12-18 | Bergstrom Sune | Pge and pgf |
-
1969
- 1969-12-12 BR BR215068/69A patent/BR6915068D0/pt unknown
-
1970
- 1970-02-19 CA CA075,313A patent/CA968348A/en not_active Expired
- 1970-02-23 IL IL33949A patent/IL33949A/en unknown
- 1970-03-05 CH CH322870A patent/CH549549A/xx not_active IP Right Cessation
- 1970-03-05 CH CH1773672A patent/CH553740A/xx not_active IP Right Cessation
- 1970-03-05 CH CH1773772A patent/CH553739A/xx not_active IP Right Cessation
- 1970-03-09 NL NL7003298A patent/NL7003298A/xx unknown
- 1970-03-10 ES ES377342A patent/ES377342A1/es not_active Expired
- 1970-03-10 GB GB01510/70A patent/GB1282661A/en not_active Expired
- 1970-03-10 GB GB58026/71A patent/GB1282662A/en not_active Expired
- 1970-03-13 FR FR7009184A patent/FR2034951B1/fr not_active Expired
- 1970-03-13 BE BE747348D patent/BE747348A/fr not_active IP Right Cessation
- 1970-03-13 DE DE19702011969 patent/DE2011969A1/de active Pending
Also Published As
Publication number | Publication date |
---|---|
CA968348A (en) | 1975-05-27 |
CH553739A (de) | 1974-09-13 |
GB1282662A (en) | 1972-07-19 |
BE747348A (fr) | 1970-09-14 |
ES377342A1 (es) | 1973-01-01 |
NL7003298A (fr) | 1970-09-16 |
FR2034951A1 (fr) | 1970-12-18 |
CH549549A (de) | 1974-05-31 |
IL33949A0 (en) | 1970-05-21 |
CH553740A (de) | 1974-09-13 |
GB1282661A (en) | 1972-07-19 |
FR2034951B1 (fr) | 1974-02-01 |
DE2011969A1 (de) | 1970-10-08 |
BR6915068D0 (pt) | 1973-05-24 |
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