ES377342A1 - Procedimiento para producir un compuesto racemico. - Google Patents
Procedimiento para producir un compuesto racemico.Info
- Publication number
- ES377342A1 ES377342A1 ES377342A ES377342A ES377342A1 ES 377342 A1 ES377342 A1 ES 377342A1 ES 377342 A ES377342 A ES 377342A ES 377342 A ES377342 A ES 377342A ES 377342 A1 ES377342 A1 ES 377342A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- atoms inclusive
- alkyl
- substituted
- inclusive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052731 fluorine Inorganic materials 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002346 iodo group Chemical group I* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80740569A | 1969-03-14 | 1969-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES377342A1 true ES377342A1 (es) | 1973-01-01 |
Family
ID=25196294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES377342A Expired ES377342A1 (es) | 1969-03-14 | 1970-03-10 | Procedimiento para producir un compuesto racemico. |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE747348A (es) |
| BR (1) | BR6915068D0 (es) |
| CA (1) | CA968348A (es) |
| CH (3) | CH553740A (es) |
| DE (1) | DE2011969A1 (es) |
| ES (1) | ES377342A1 (es) |
| FR (1) | FR2034951B1 (es) |
| GB (2) | GB1282661A (es) |
| IL (1) | IL33949A (es) |
| NL (1) | NL7003298A (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3983153A (en) * | 1969-03-14 | 1976-09-28 | The Upjohn Company | Racemic fluoro-substituted PGE2 analogs |
| US3993687A (en) * | 1969-03-14 | 1976-11-23 | The Upjohn Company | Racemic fluoro-substituted PGB2 analogs |
| US4008263A (en) * | 1969-03-14 | 1977-02-15 | The Upjohn Company | Racemic fluoro-substituted PGF2 .sub.α analogs |
| US3940438A (en) * | 1971-05-24 | 1976-02-24 | Alza Corporation | Crystalline racemic 9α,11α,15(S)-trihydroxy-5-cis,13-trans-prostadienoic acid |
| US3988361A (en) * | 1971-11-16 | 1976-10-26 | The Upjohn Company | 8β-PGE2 and related compounds |
| GB1396206A (en) * | 1972-04-27 | 1975-06-04 | Upjohn Co | Prostaglandins and the preparation thereof |
| US4001300A (en) * | 1975-02-24 | 1977-01-04 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGF2 analogs |
| US4056557A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGF1 analogs |
| US4056555A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGA2 analogs |
| US4056556A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGE2 analogs |
| US4056554A (en) * | 1975-02-24 | 1977-11-01 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-13,14-dihydro-PGF1, analogs |
| US4059614A (en) * | 1975-02-24 | 1977-11-22 | The Upjohn Company | 2,2-Difluoro-16-phenoxy-PGE1 analogs |
| US4053500A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGF1α analogs |
| US4013695A (en) * | 1975-10-02 | 1977-03-22 | The Upjohn Company | 4,4,5,5-Tetradehydro-PGE1 analogs |
| US4053502A (en) * | 1975-10-02 | 1977-10-11 | The Upjohn Company | 4,4,5,5-Tetradehydro-ω-aryl-PGE1 analogs |
| US5990168A (en) * | 1996-04-18 | 1999-11-23 | Alberta Cancer Board | Methods and compositions for the treatment of ataxia telangiectasia |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3069322A (en) * | 1958-05-28 | 1962-12-18 | Bergstrom Sune | Pge and pgf |
-
1969
- 1969-12-12 BR BR215068/69A patent/BR6915068D0/pt unknown
-
1970
- 1970-02-19 CA CA075,313A patent/CA968348A/en not_active Expired
- 1970-02-23 IL IL33949A patent/IL33949A/en unknown
- 1970-03-05 CH CH1773672A patent/CH553740A/xx not_active IP Right Cessation
- 1970-03-05 CH CH322870A patent/CH549549A/xx not_active IP Right Cessation
- 1970-03-05 CH CH1773772A patent/CH553739A/xx not_active IP Right Cessation
- 1970-03-09 NL NL7003298A patent/NL7003298A/xx unknown
- 1970-03-10 GB GB01510/70A patent/GB1282661A/en not_active Expired
- 1970-03-10 GB GB58026/71A patent/GB1282662A/en not_active Expired
- 1970-03-10 ES ES377342A patent/ES377342A1/es not_active Expired
- 1970-03-13 BE BE747348D patent/BE747348A/xx not_active IP Right Cessation
- 1970-03-13 DE DE19702011969 patent/DE2011969A1/de active Pending
- 1970-03-13 FR FR7009184A patent/FR2034951B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2034951A1 (es) | 1970-12-18 |
| FR2034951B1 (es) | 1974-02-01 |
| GB1282662A (en) | 1972-07-19 |
| BE747348A (fr) | 1970-09-14 |
| BR6915068D0 (pt) | 1973-05-24 |
| CH553740A (de) | 1974-09-13 |
| CA968348A (en) | 1975-05-27 |
| CH553739A (de) | 1974-09-13 |
| IL33949A (en) | 1976-06-30 |
| IL33949A0 (en) | 1970-05-21 |
| CH549549A (de) | 1974-05-31 |
| GB1282661A (en) | 1972-07-19 |
| DE2011969A1 (de) | 1970-10-08 |
| NL7003298A (es) | 1970-09-16 |
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