IL32535A - A process for the preparation of epimeric 4-((5-substituted-4(s)-quinuclidin-2-yl)hydroxymethyl)-quinoline derivatives - Google Patents

A process for the preparation of epimeric 4-((5-substituted-4(s)-quinuclidin-2-yl)hydroxymethyl)-quinoline derivatives

Info

Publication number
IL32535A
IL32535A IL32535A IL3253569A IL32535A IL 32535 A IL32535 A IL 32535A IL 32535 A IL32535 A IL 32535A IL 3253569 A IL3253569 A IL 3253569A IL 32535 A IL32535 A IL 32535A
Authority
IL
Israel
Prior art keywords
quinuclidin
epimeric
hydroxymethyl
substituted
preparation
Prior art date
Application number
IL32535A
Other languages
English (en)
Other versions
IL32535A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL32535A0 publication Critical patent/IL32535A0/xx
Publication of IL32535A publication Critical patent/IL32535A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms
    • C07D211/76Oxygen atoms attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94Oxygen atom, e.g. piperidine N-oxide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C07D453/04Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02JCIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/30Circuit arrangements or systems for wireless supply or distribution of electric power using light, e.g. lasers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Power Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
IL32535A 1968-07-02 1969-07-02 A process for the preparation of epimeric 4-((5-substituted-4(s)-quinuclidin-2-yl)hydroxymethyl)-quinoline derivatives IL32535A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74191468A 1968-07-02 1968-07-02

Publications (2)

Publication Number Publication Date
IL32535A0 IL32535A0 (en) 1969-09-25
IL32535A true IL32535A (en) 1975-05-22

Family

ID=24982733

Family Applications (4)

Application Number Title Priority Date Filing Date
IL32535A IL32535A (en) 1968-07-02 1969-07-02 A process for the preparation of epimeric 4-((5-substituted-4(s)-quinuclidin-2-yl)hydroxymethyl)-quinoline derivatives
IL43885A IL43885A0 (en) 1968-07-02 1973-12-21 Novel quinoline derivatives and their preparation
IL43886A IL43886A0 (en) 1968-07-02 1973-12-21 The preparation of quinoline derivatives
IL43884A IL43884A0 (en) 1968-07-02 1973-12-21 Novel quinoline derivatives and their preparation

Family Applications After (3)

Application Number Title Priority Date Filing Date
IL43885A IL43885A0 (en) 1968-07-02 1973-12-21 Novel quinoline derivatives and their preparation
IL43886A IL43886A0 (en) 1968-07-02 1973-12-21 The preparation of quinoline derivatives
IL43884A IL43884A0 (en) 1968-07-02 1973-12-21 Novel quinoline derivatives and their preparation

Country Status (14)

Country Link
JP (1) JPS497160B1 (nl)
AT (4) AT323338B (nl)
BE (1) BE735451A (nl)
CA (3) CA954516A (nl)
CH (4) CH559183A5 (nl)
DE (1) DE1933600A1 (nl)
DK (1) DK129235B (nl)
FR (2) FR2012152B1 (nl)
GB (2) GB1280201A (nl)
IE (3) IE33813B1 (nl)
IL (4) IL32535A (nl)
NL (1) NL162384C (nl)
PH (3) PH11413A (nl)
SE (3) SE376612B (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857837A (en) * 1968-07-02 1974-12-31 Hoffmann La Roche Processes and intermediated for quinine, quinidine, isomers and derivatives thereof
JPS5147064U (nl) * 1974-10-04 1976-04-07
US4357471A (en) 1976-12-17 1982-11-02 Rohm And Haas Company Azaspiro compounds
US4400512A (en) * 1976-12-17 1983-08-23 Rohm And Haas Company Azaspiro compounds
US4374991A (en) 1976-12-17 1983-02-22 Rohm And Haas Company 2,6-Dimethylpiperidinyl-N-carbobutoxymethyl urea
NL7908031A (nl) * 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
US4405630A (en) * 1980-12-29 1983-09-20 Rohm And Haas Company Arthropod repellent compositions and methods

Also Published As

Publication number Publication date
CA974994A (en) 1975-09-23
IE33814B1 (en) 1974-11-13
IL43886A0 (en) 1974-03-14
FR2108178A1 (nl) 1972-05-19
IL32535A0 (en) 1969-09-25
NL162384C (nl) 1980-05-16
IL43885A0 (en) 1974-03-14
IL43884A0 (en) 1974-03-14
IE33814L (en) 1970-01-02
PH10708A (en) 1977-08-24
FR2108178B1 (nl) 1974-03-22
DK129235B (da) 1974-09-16
CH533622A (de) 1973-02-15
IE33812L (en) 1970-01-02
FR2012152A1 (nl) 1970-03-13
SE364044B (nl) 1974-02-11
CA954517A (en) 1974-09-10
GB1280203A (en) 1972-07-05
NL162384B (nl) 1979-12-17
CH559181A5 (nl) 1975-02-28
SE376612B (nl) 1975-06-02
CH559183A5 (nl) 1975-02-28
JPS497160B1 (nl) 1974-02-19
AT300813B (de) 1972-07-15
SE375776B (nl) 1975-04-28
CA954516A (en) 1974-09-10
IE33812B1 (en) 1974-11-13
AT319482B (de) 1974-12-27
NL6910136A (nl) 1970-01-06
CH559184A5 (nl) 1975-02-28
DK129235C (nl) 1975-02-10
AT323338B (de) 1975-07-10
PH11413A (en) 1977-12-27
DE1933600A1 (de) 1970-01-08
GB1280201A (en) 1972-07-05
PH10255A (en) 1976-10-14
FR2012152B1 (nl) 1973-08-10
AT323337B (de) 1975-07-10
IE33813B1 (en) 1974-11-13
BE735451A (nl) 1970-01-02
IE33813L (en) 1970-01-02

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