IL325136A - תרכובות פיראזולו-פירימידינון לשימוש בשיטות לעיכוב קינאז week1 a - Google Patents

תרכובות פיראזולו-פירימידינון לשימוש בשיטות לעיכוב קינאז week1 a

Info

Publication number
IL325136A
IL325136A IL325136A IL32513625A IL325136A IL 325136 A IL325136 A IL 325136A IL 325136 A IL325136 A IL 325136A IL 32513625 A IL32513625 A IL 32513625A IL 325136 A IL325136 A IL 325136A
Authority
IL
Israel
Prior art keywords
pct
nmr
cancer
alkyl
mhz
Prior art date
Application number
IL325136A
Other languages
English (en)
Original Assignee
Acrivon Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acrivon Therapeutics Inc filed Critical Acrivon Therapeutics Inc
Publication of IL325136A publication Critical patent/IL325136A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
IL325136A 2023-06-09 2024-06-07 תרכובות פיראזולו-פירימידינון לשימוש בשיטות לעיכוב קינאז week1 a IL325136A (he)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202363472105P 2023-06-09 2023-06-09
US202363608086P 2023-12-08 2023-12-08
US202463635197P 2024-04-17 2024-04-17
PCT/US2024/033065 WO2024254490A1 (en) 2023-06-09 2024-06-07 Pyrazolo-pyrimidinone compounds for use in methods of inhibiting wee1 a kinase

Publications (1)

Publication Number Publication Date
IL325136A true IL325136A (he) 2026-02-01

Family

ID=91853604

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325136A IL325136A (he) 2023-06-09 2024-06-07 תרכובות פיראזולו-פירימידינון לשימוש בשיטות לעיכוב קינאז week1 a

Country Status (9)

Country Link
EP (1) EP4724443A1 (he)
KR (1) KR20260039689A (he)
CN (1) CN121752567A (he)
AU (1) AU2024284667A1 (he)
CO (1) CO2026000188A2 (he)
IL (1) IL325136A (he)
MX (1) MX2025014761A (he)
TW (1) TW202504610A (he)
WO (1) WO2024254490A1 (he)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018133829A1 (zh) * 2017-01-23 2018-07-26 南京明德新药研发股份有限公司 作为Wee1抑制剂的1,2-二氢-3H-吡唑[3,4-d]嘧啶-3-酮衍生物
WO2019074979A1 (en) * 2017-10-09 2019-04-18 Girafpharma, Llc HETEROCYCLIC COMPOUNDS AND USES THEREOF

Also Published As

Publication number Publication date
AU2024284667A1 (en) 2026-01-15
EP4724443A1 (en) 2026-04-15
WO2024254490A1 (en) 2024-12-12
TW202504610A (zh) 2025-02-01
CO2026000188A2 (es) 2026-04-06
CN121752567A (zh) 2026-03-27
MX2025014761A (es) 2026-01-07
KR20260039689A (ko) 2026-03-20

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