IL311694A - A radiolabeled fibroblast activation protein ligand - Google Patents
A radiolabeled fibroblast activation protein ligandInfo
- Publication number
- IL311694A IL311694A IL311694A IL31169424A IL311694A IL 311694 A IL311694 A IL 311694A IL 311694 A IL311694 A IL 311694A IL 31169424 A IL31169424 A IL 31169424A IL 311694 A IL311694 A IL 311694A
- Authority
- IL
- Israel
- Prior art keywords
- radiolabelled
- activation protein
- fibroblast activation
- protein ligands
- ligands
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 210000002950 fibroblast Anatomy 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/06—Aluminium compounds
- C07F5/069—Aluminium compounds without C-aluminium linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21200719 | 2021-10-04 | ||
| EP22151771 | 2022-01-17 | ||
| PCT/EP2022/077598 WO2023057457A1 (en) | 2021-10-04 | 2022-10-04 | Radiolabelled fibroblast activation protein ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL311694A true IL311694A (en) | 2024-05-01 |
Family
ID=84330437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL311694A IL311694A (en) | 2021-10-04 | 2022-10-04 | A radiolabeled fibroblast activation protein ligand |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR20240093543A (ko) |
| AU (1) | AU2022358921A1 (ko) |
| CA (1) | CA3234394A1 (ko) |
| IL (1) | IL311694A (ko) |
| WO (1) | WO2023057457A1 (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240189460A1 (en) * | 2022-09-23 | 2024-06-13 | Nuclidium Ag | High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof |
| CN116925041A (zh) * | 2023-06-12 | 2023-10-24 | 上海交通大学医学院附属仁济医院 | 靶向成纤维细胞激活蛋白的氟标记放射性药物前体、放射性标记化合物及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1942186B (zh) | 2004-03-09 | 2010-10-06 | 国家卫生研究院 | 吡咯烷化合物 |
| WO2013107820A1 (en) | 2012-01-17 | 2013-07-25 | Universiteit Antwerpen | Novel fap inhibitors |
| CN110291401B (zh) | 2016-12-14 | 2023-04-11 | 普渡研究基金会 | 成纤维细胞活化蛋白(fap)-靶向成像和治疗 |
| CN116617420A (zh) | 2017-10-23 | 2023-08-22 | 约翰霍普金斯大学 | 靶向成纤维细胞活化蛋白α的化合物、药物组合物及用途 |
| MX2020006128A (es) | 2017-12-15 | 2020-09-21 | Praxis Biotech LLC | Inhibidores de la proteina de activacion de fibroblastos. |
| AU2019219057B2 (en) | 2018-02-06 | 2022-11-24 | Universität Heidelberg | FAP inhibitor |
| WO2019154859A1 (en) | 2018-02-06 | 2019-08-15 | Universität Heidelberg | Fap inhibitor |
| WO2021160825A1 (en) * | 2020-02-12 | 2021-08-19 | Philochem Ag | Fibroblast activation protein ligands for targeted delivery applications |
-
2022
- 2022-10-04 IL IL311694A patent/IL311694A/en unknown
- 2022-10-04 CA CA3234394A patent/CA3234394A1/en active Pending
- 2022-10-04 WO PCT/EP2022/077598 patent/WO2023057457A1/en active Application Filing
- 2022-10-04 AU AU2022358921A patent/AU2022358921A1/en active Pending
- 2022-10-04 KR KR1020247015053A patent/KR20240093543A/ko unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240093543A (ko) | 2024-06-24 |
| CA3234394A1 (en) | 2023-04-13 |
| AU2022358921A1 (en) | 2024-05-02 |
| WO2023057457A1 (en) | 2023-04-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL311694A (en) | A radiolabeled fibroblast activation protein ligand | |
| IL289675A (en) | Compounds comprising a protein ligand for fibroblast activation and its use | |
| HUE058835T2 (hu) | Fibroblaszt aktiváló protein ligandumok célzott szállítási alkalmazásokhoz | |
| IL289673A (en) | Compounds comprising a protein ligand for fibroblast activation and its use | |
| IL292113A (en) | Bicyclic drug ligand conjugates | |
| IL286635A (en) | tyk2 pseudokinase ligands | |
| IL305810A (en) | Neoantigenic peptides from cancer | |
| SG11202108619SA (en) | Tyk2 pseudokinase ligands | |
| IL291719A (en) | mgl pet ligands are radioactively labeled | |
| IL304241A (en) | Heterotandem bicyclic peptide complexes | |
| GB202005876D0 (en) | Protein degradation | |
| IL309559A (en) | Dimeric protein complexes and their uses | |
| IL287158A (en) | A multi-specific antigen for binding protein complexes | |
| EP3947429A4 (en) | CLEC9A-BASED CHIMERA PROTEIN COMPLEXES | |
| GB202118147D0 (en) | Bicyclic peptide ligands specific for MMP9 | |
| GB202019997D0 (en) | Bicyclic peptide ligands specific for MMP9 | |
| GB202101828D0 (en) | Protein | |
| GB202101826D0 (en) | Protein | |
| GB202101825D0 (en) | Protein | |
| IL307945A (en) | NKG2D antibody-ligand region fusion protein | |
| IL307944A (en) | NKG2D antibody-ligand region fusion protein | |
| GB201918501D0 (en) | Bicycle peptide ligands specific for TGFbeta | |
| AU2019904219A0 (en) | Radiolabelled targeting ligands and complexes thereof | |
| GB201914875D0 (en) | Bicyclic peptide ligand drug conjugates | |
| GB201914196D0 (en) | Bicyclic peptide ligand Drug conjugates |