IL309044A - Preparations and methods for enzymatic nucleic acid synthesis - Google Patents
Preparations and methods for enzymatic nucleic acid synthesisInfo
- Publication number
- IL309044A IL309044A IL309044A IL30904423A IL309044A IL 309044 A IL309044 A IL 309044A IL 309044 A IL309044 A IL 309044A IL 30904423 A IL30904423 A IL 30904423A IL 309044 A IL309044 A IL 309044A
- Authority
- IL
- Israel
- Prior art keywords
- nucleic acid
- polymerase
- substrate
- dna
- template independent
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
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|---|---|---|---|
| US202163210429P | 2021-06-14 | 2021-06-14 | |
| PCT/US2022/033312 WO2022266019A2 (en) | 2021-06-14 | 2022-06-13 | Compositions and methods for enzymatic nucleic acid synthesis |
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| IL309044A true IL309044A (en) | 2024-02-01 |
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| IL309044A IL309044A (en) | 2021-06-14 | 2022-06-13 | Preparations and methods for enzymatic nucleic acid synthesis |
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| EP (2) | EP4355894A2 (https=) |
| JP (2) | JP2024522222A (https=) |
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| MX (2) | MX2023014873A (https=) |
| WO (2) | WO2022266019A2 (https=) |
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| WO2026008711A2 (en) * | 2024-07-02 | 2026-01-08 | Dna Script | Filtering device and method for polynucleotide enzymatic synthesis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5808045A (en) | 1994-09-02 | 1998-09-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
| US5763594A (en) | 1994-09-02 | 1998-06-09 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
| DE10215035A1 (de) | 2002-04-05 | 2003-10-23 | Roche Diagnostics Gmbh | Rekombinante terminale Deoxynukleotidyltransferase mit verbesserter Funktionalität |
| EP3363904B1 (en) * | 2014-01-31 | 2019-10-23 | Swift Biosciences, Inc. | Improved methods for processing dna substrates |
| EP3699283A1 (en) | 2014-10-20 | 2020-08-26 | Molecular Assemblies Inc. | Modified template-independent enzymes for polydeoxynucleotide systhesis |
| JP6920275B2 (ja) * | 2015-07-13 | 2021-08-18 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 核酸を用いた回収可能な情報記憶のための方法 |
| US12227775B2 (en) * | 2017-05-22 | 2025-02-18 | The Charles Stark Draper Laboratory, Inc. | Modified template-independent DNA polymerase |
| GB201901501D0 (en) * | 2019-02-04 | 2019-03-27 | Nuclera Nucleics Ltd | Modified terminal deoxynucleotidyl transferase (TdT) enzymes |
| JP2020150801A (ja) * | 2019-03-18 | 2020-09-24 | 国立大学法人東京工業大学 | Ｄｎａの酵素合成法 |
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2022
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- 2022-06-13 JP JP2023577232A patent/JP2024522222A/ja active Pending
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- 2022-06-13 KR KR1020247000863A patent/KR20240021866A/ko active Pending
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- 2022-06-13 US US18/569,914 patent/US20240301457A1/en active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20240022552A (ko) | 2024-02-20 |
| WO2022266019A2 (en) | 2022-12-22 |
| WO2022266020A3 (en) | 2023-03-09 |
| JP2024522217A (ja) | 2024-06-11 |
| EP4355894A2 (en) | 2024-04-24 |
| EP4355895A2 (en) | 2024-04-24 |
| MX2023014874A (es) | 2024-04-29 |
| MX2023014873A (es) | 2024-04-29 |
| JP2024522222A (ja) | 2024-06-11 |
| WO2022266020A2 (en) | 2022-12-22 |
| WO2022266019A3 (en) | 2023-02-02 |
| CN117881790A (zh) | 2024-04-12 |
| US20240301457A1 (en) | 2024-09-12 |
| US20240384318A1 (en) | 2024-11-21 |
| KR20240021866A (ko) | 2024-02-19 |
| AU2022293386A1 (en) | 2023-12-21 |
| CN118103519A (zh) | 2024-05-28 |
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