IL30764A - 1-(4-acylamino-2-substituted-phenoxy)-3-amino-2-propanol derivatives,process for their manufacture and pharmaceutical compositions containing them - Google Patents

1-(4-acylamino-2-substituted-phenoxy)-3-amino-2-propanol derivatives,process for their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL30764A
IL30764A IL30764A IL3076468A IL30764A IL 30764 A IL30764 A IL 30764A IL 30764 A IL30764 A IL 30764A IL 3076468 A IL3076468 A IL 3076468A IL 30764 A IL30764 A IL 30764A
Authority
IL
Israel
Prior art keywords
acylamino
phenoxy
amino
substituted
manufacture
Prior art date
Application number
IL30764A
Other languages
English (en)
Other versions
IL30764A0 (en
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of IL30764A0 publication Critical patent/IL30764A0/xx
Publication of IL30764A publication Critical patent/IL30764A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL30764A 1967-09-27 1968-09-26 1-(4-acylamino-2-substituted-phenoxy)-3-amino-2-propanol derivatives,process for their manufacture and pharmaceutical compositions containing them IL30764A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43927/67A GB1199037A (en) 1967-09-27 1967-09-27 Alkanolamine Derivatives

Publications (2)

Publication Number Publication Date
IL30764A0 IL30764A0 (en) 1968-11-27
IL30764A true IL30764A (en) 1972-11-28

Family

ID=10430973

Family Applications (1)

Application Number Title Priority Date Filing Date
IL30764A IL30764A (en) 1967-09-27 1968-09-26 1-(4-acylamino-2-substituted-phenoxy)-3-amino-2-propanol derivatives,process for their manufacture and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US3712927A (xx)
JP (1) JPS5220459B1 (xx)
AT (3) AT298455B (xx)
BE (1) BE721560A (xx)
BR (1) BR6802575D0 (xx)
DE (1) DE1793511A1 (xx)
DK (1) DK124942B (xx)
FR (1) FR333F (xx)
GB (1) GB1199037A (xx)
IE (1) IE32739B1 (xx)
IL (1) IL30764A (xx)
NL (1) NL6813616A (xx)
NO (1) NO123893B (xx)
PL (1) PL71423B1 (xx)
SE (1) SE357361B (xx)
SU (1) SU385433A3 (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1311521A (en) * 1970-02-13 1973-03-28 Ici Ltd Alkanolamine derivatives
SE354851B (xx) * 1970-02-18 1973-03-26 Haessle Ab
US3864398A (en) * 1972-05-01 1975-02-04 Teikoku Hormone Mfg Co Ltd Process for the preparation of acylamino alkanol derivatives
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
DE2324584A1 (de) * 1972-06-08 1974-01-10 Ciba Geigy Ag Neue amine und verfahren zu ihrer herstellung
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
US4171374A (en) * 1972-12-15 1979-10-16 Imperial Chemical Industries Limited Alkanolamine derivatives
US4131685A (en) * 1972-12-15 1978-12-26 Imperial Chemical Industries Limited Pharmaceutical compositions and uses of alkanolamine derivatives
US4167581A (en) * 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
US4083992A (en) * 1972-12-15 1978-04-11 Imperial Chemical Industries Limited Alkanolamine derivatives
US4016286A (en) * 1973-02-28 1977-04-05 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and their use as adrenolytics and hypotensives
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
US4016202A (en) * 1973-02-28 1977-04-05 Boehringer Ingelheim Gmbh 1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof
US4084002A (en) * 1973-02-28 1978-04-11 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-phenoxy-2-hydroxy-3-alkynylamino-propane and method of use
US3957870A (en) * 1973-07-19 1976-05-18 Imperial Chemical Industries Limited Organic compounds
US4039683A (en) * 1973-08-21 1977-08-02 Merck Patent Gesellschaft Mit Beschrankter Haftung Phenoxypropionic acid derivatives and pharmaceutical preparations containing same
US4239700A (en) * 1978-10-10 1980-12-16 Texaco Development Corp. Isatoic anhydride derivatives and use as chain-extenders
DE3015991A1 (de) 1980-04-25 1981-11-05 C.H. Boehringer Sohn, 6507 Ingelheim Neue 1-aryloxy-3-alkylamino-2-propanole und verfahren zur ihrer herstellung
DE3133678A1 (de) * 1981-08-26 1983-03-17 Boehringer Ingelheim KG, 6507 Ingelheim Neue l-aryloxy-3-alkylamino-2-propanole und verfahren zu ihrer herstellung
EP0077529B1 (de) * 1981-10-16 1985-07-17 Sanol Schwarz GmbH Arzneimittelformulierung
FR2555179B1 (fr) * 1983-11-21 1986-11-21 Carpibem Nouveaux (carbethoxy-2 furyl- ou benzofuryl-carboxamido-4 phenoxy)-1 amino-3 propanols-2 : leurs preparations et leurs applications en therapeutique
JPS6193417U (xx) * 1984-11-24 1986-06-17
US5545412A (en) * 1985-01-07 1996-08-13 Syntex (U.S.A.) Inc. N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor
US4897355A (en) * 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
DE3640829A1 (de) * 1986-11-28 1988-06-09 Boehringer Ingelheim Kg Neue 1-aryloxy-3-amino-2-propanole, ihre herstellung und verwendung
US5202487A (en) * 1988-09-13 1993-04-13 L'oreal 2-substituted para-aminophenols and their use for dyeing keratinous fibres
FR2637282B1 (fr) * 1988-09-13 1990-12-07 Oreal Para-aminophenols 2-substitues et leur utilisation pour la teinture des fibres keratiniques
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
IL126458A (en) 1996-04-09 2004-06-20 Nps Pharma Inc Calcium receptor inhibiting calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds
UY24949A1 (es) 1997-04-08 2001-04-30 Smithkline Beecham Corp Compuestos calcilíticos

Also Published As

Publication number Publication date
IE32739L (en) 1969-03-27
GB1199037A (en) 1970-07-15
IE32739B1 (en) 1973-11-14
DE1793511A1 (de) 1972-03-16
FR333F (xx) 1970-10-26
AT291968B (de) 1971-08-10
BR6802575D0 (pt) 1973-04-26
PL71423B1 (en) 1974-06-29
IL30764A0 (en) 1968-11-27
DK124942B (da) 1972-12-11
US3712927A (en) 1973-01-23
JPS5220459B1 (xx) 1977-06-03
NL6813616A (xx) 1969-03-31
AT298456B (de) 1972-05-10
SE357361B (xx) 1973-06-25
AT298455B (de) 1972-05-10
BE721560A (xx) 1969-03-27
SU385433A3 (xx) 1973-05-29
NO123893B (xx) 1972-01-31

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