IL30231A - 3-Amino-1,2-benzaziothiazoles N -duclear, their preparation and pharmaceutical preparations containing them - Google Patents
3-Amino-1,2-benzaziothiazoles N -duclear, their preparation and pharmaceutical preparations containing themInfo
- Publication number
- IL30231A IL30231A IL6830231A IL3023168A IL30231A IL 30231 A IL30231 A IL 30231A IL 6830231 A IL6830231 A IL 6830231A IL 3023168 A IL3023168 A IL 3023168A IL 30231 A IL30231 A IL 30231A
- Authority
- IL
- Israel
- Prior art keywords
- carbon
- nitrogen atom
- radicals
- stands
- aliphatic
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title description 2
- 238000002360 preparation method Methods 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 6
- 150000001412 amines Chemical class 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 230000001717 pathogenic effect Effects 0.000 claims description 2
- 229910052799 carbon Inorganic materials 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 2
- 125000001931 aliphatic group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 150000001723 carbon free-radicals Chemical class 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 239000004215 Carbon black (E152) Substances 0.000 claims 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 150000001450 anions Chemical class 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 239000012442 inert solvent Substances 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 150000003254 radicals Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000003921 oil Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000011541 reaction mixture Substances 0.000 description 3
- CSNIZNHTOVFARY-UHFFFAOYSA-N 1,2-benzothiazole Chemical compound C1=CC=C2C=NSC2=C1 CSNIZNHTOVFARY-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- KNIUHBNRWZGIQQ-UHFFFAOYSA-N 7-diethoxyphosphinothioyloxy-4-methylchromen-2-one Chemical compound CC1=CC(=O)OC2=CC(OP(=S)(OCC)OCC)=CC=C21 KNIUHBNRWZGIQQ-UHFFFAOYSA-N 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- VCKXNCZAOLRBCY-UHFFFAOYSA-N Cl.Cl.Cl.Br Chemical compound Cl.Cl.Cl.Br VCKXNCZAOLRBCY-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000223238 Trichophyton Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 150000001348 alkyl chlorides Chemical class 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- GEYMMMXKROUBAI-UHFFFAOYSA-N chlorane Chemical compound Cl.Cl.Cl.Cl.Cl GEYMMMXKROUBAI-UHFFFAOYSA-N 0.000 description 1
- HRYZWHHZPQKTII-UHFFFAOYSA-N chloroethane Chemical compound CCCl HRYZWHHZPQKTII-UHFFFAOYSA-N 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229960003750 ethyl chloride Drugs 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1967F0053242 DE1670907B2 (de) | 1967-08-16 | 1967-08-16 | N-disubstituierte 3-amino-1,2benzisothiazole und verfahren in ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL30231A0 IL30231A0 (en) | 1968-08-22 |
| IL30231A true IL30231A (en) | 1972-01-27 |
Family
ID=7106127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL6830231A IL30231A (en) | 1967-08-16 | 1968-06-23 | 3-Amino-1,2-benzaziothiazoles N -duclear, their preparation and pharmaceutical preparations containing them |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3787572A (OSRAM) |
| AT (1) | AT279608B (OSRAM) |
| BE (1) | BE719566A (OSRAM) |
| BR (1) | BR6801542D0 (OSRAM) |
| CH (1) | CH516581A (OSRAM) |
| DE (1) | DE1670907B2 (OSRAM) |
| ES (1) | ES357317A1 (OSRAM) |
| FR (2) | FR1601118A (OSRAM) |
| GB (1) | GB1229996A (OSRAM) |
| IL (1) | IL30231A (OSRAM) |
| NL (1) | NL6811549A (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2609864C2 (de) * | 1976-03-10 | 1984-02-16 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von 3-Amino-1,2-benzisothiazolen |
| US4112105A (en) * | 1977-05-04 | 1978-09-05 | Sterling Drug Inc. | Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles |
| US4411901A (en) * | 1981-12-23 | 1983-10-25 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
| US4590196A (en) * | 1984-08-23 | 1986-05-20 | Bristol-Myers Company | Analgesic 1,2-benzisothiazol-3-ylpiperazine derivatives |
| PE20070847A1 (es) * | 2005-11-21 | 2007-09-21 | Basf Ag | Compuestos derivados de 3-amino-1,2-bencisotiazol como insecticidas |
-
1967
- 1967-08-16 DE DE1967F0053242 patent/DE1670907B2/de active Granted
-
1968
- 1968-06-20 CH CH915368A patent/CH516581A/de not_active IP Right Cessation
- 1968-06-23 IL IL6830231A patent/IL30231A/en unknown
- 1968-07-31 GB GB1229996D patent/GB1229996A/en not_active Expired
- 1968-07-31 AT AT747168A patent/AT279608B/de not_active IP Right Cessation
- 1968-08-14 NL NL6811549A patent/NL6811549A/xx unknown
- 1968-08-16 BE BE719566D patent/BE719566A/xx unknown
- 1968-08-16 ES ES357317A patent/ES357317A1/es not_active Expired
- 1968-08-16 BR BR201542/68A patent/BR6801542D0/pt unknown
- 1968-08-18 FR FR1601118D patent/FR1601118A/fr not_active Expired
- 1968-11-15 FR FR173955A patent/FR8097M/fr not_active Expired
-
1971
- 1971-09-29 US US00182246A patent/US3787572A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES357317A1 (es) | 1970-03-16 |
| BE719566A (OSRAM) | 1969-02-17 |
| AT279608B (de) | 1970-03-10 |
| IL30231A0 (en) | 1968-08-22 |
| NL6811549A (OSRAM) | 1969-02-18 |
| DE1670907A1 (de) | 1971-03-18 |
| CH516581A (de) | 1971-12-15 |
| FR1601118A (OSRAM) | 1970-08-10 |
| DE1670907B2 (de) | 1976-07-22 |
| FR8097M (OSRAM) | 1970-07-20 |
| BR6801542D0 (pt) | 1973-02-22 |
| GB1229996A (OSRAM) | 1971-04-28 |
| US3787572A (en) | 1974-01-22 |
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