IL299544A - Modified release formulations of modified forms of trimetazidine - Google Patents
Modified release formulations of modified forms of trimetazidineInfo
- Publication number
- IL299544A IL299544A IL299544A IL29954422A IL299544A IL 299544 A IL299544 A IL 299544A IL 299544 A IL299544 A IL 299544A IL 29954422 A IL29954422 A IL 29954422A IL 299544 A IL299544 A IL 299544A
- Authority
- IL
- Israel
- Prior art keywords
- imb
- hours
- trimetazidine
- dose
- hpmc
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063046117P | 2020-06-30 | 2020-06-30 | |
| US202063046115P | 2020-06-30 | 2020-06-30 | |
| US202163183299P | 2021-05-03 | 2021-05-03 | |
| US202163183294P | 2021-05-03 | 2021-05-03 | |
| PCT/US2021/039303 WO2022005926A1 (en) | 2020-06-30 | 2021-06-28 | Modified release formulations of modified forms of trimetazidine |
Publications (1)
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|---|---|
| IL299544A true IL299544A (en) | 2023-02-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL299544A IL299544A (en) | 2020-06-30 | 2021-06-28 | Modified release formulations of modified forms of trimetazidine |
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| Country | Link |
|---|---|
| EP (1) | EP4171232A4 (de) |
| JP (1) | JP2023531802A (de) |
| KR (1) | KR20230028535A (de) |
| CN (1) | CN116234555A (de) |
| AU (1) | AU2021299197A1 (de) |
| CA (1) | CA3187827A1 (de) |
| IL (1) | IL299544A (de) |
| WO (1) | WO2022005926A1 (de) |
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| KR20250035269A (ko) * | 2023-09-05 | 2025-03-12 | 주식회사 뉴캔서큐어바이오 | 트리메타지딘을 포함하는 코팅정 조성물 및 이의 제조방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4743321B2 (ja) * | 2006-06-09 | 2011-08-10 | ウーツェーベー ファルマ ゲーエムベーハー | フェソテロジンを含む安定した医薬組成物 |
| PE20080669A1 (es) * | 2006-09-08 | 2008-07-18 | Drugtech Corp | Composicion de liberacion sostenida que comprende levodopa |
| ITFI20130184A1 (it) * | 2013-08-01 | 2015-02-02 | Valpharma Internat S P A | Una formulazione farmaceutica di gliclazide a rilascio modificato, somministrabile per via orale, e suo metodo di produzione. |
| ES2884973T3 (es) * | 2016-03-09 | 2021-12-13 | Nls Pharmaceutics Ag | Comprimido multicapa de mazindol de IR/SR y su utilización para el tratamiento del trastorno por déficit de atención/hiperactividad (ADHD) |
| EP4092013A1 (de) * | 2017-06-20 | 2022-11-23 | Imbria Pharmaceuticals, Inc. | Zusammensetzungen und verfahren zur erhöhung der effizienz des herzmetabolismus |
| US10980747B2 (en) * | 2017-11-27 | 2021-04-20 | Shin-Etsu Chemical Co., Ltd. | Composition for solid preparation, solid preparation, and method for producing the same |
| CN109908096A (zh) * | 2017-12-12 | 2019-06-21 | 武汉武药科技有限公司 | 一种盐酸曲美他嗪缓释片及其制备方法 |
| WO2020081361A1 (en) * | 2018-10-17 | 2020-04-23 | Imbria Pharmaceuticals, Inc. | Methods of treating rheumatic diseases using trimetazidine-based compounds |
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2021
- 2021-06-28 AU AU2021299197A patent/AU2021299197A1/en active Pending
- 2021-06-28 CA CA3187827A patent/CA3187827A1/en active Pending
- 2021-06-28 CN CN202180051890.7A patent/CN116234555A/zh active Pending
- 2021-06-28 WO PCT/US2021/039303 patent/WO2022005926A1/en not_active Ceased
- 2021-06-28 KR KR1020237003154A patent/KR20230028535A/ko active Pending
- 2021-06-28 IL IL299544A patent/IL299544A/en unknown
- 2021-06-28 EP EP21832842.5A patent/EP4171232A4/de active Pending
- 2021-06-28 JP JP2022581463A patent/JP2023531802A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023531802A (ja) | 2023-07-25 |
| KR20230028535A (ko) | 2023-02-28 |
| CN116234555A (zh) | 2023-06-06 |
| EP4171232A4 (de) | 2024-07-24 |
| CA3187827A1 (en) | 2022-01-06 |
| WO2022005926A1 (en) | 2022-01-06 |
| AU2021299197A1 (en) | 2023-02-02 |
| EP4171232A1 (de) | 2023-05-03 |
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| INC | PrM-NIFEDIPINE ER | |
| Tablets et al. | PrTEVA-DILTIAZEM XC | |
| Agent | KOMBOGLYZE® |