IL299009A - Methods and preparations for the prevention and treatment of myopia (myopia) with berberine, berbridicannane alkaloid, and their derivatives - Google Patents

Methods and preparations for the prevention and treatment of myopia (myopia) with berberine, berbridicannane alkaloid, and their derivatives

Info

Publication number
IL299009A
IL299009A IL299009A IL29900922A IL299009A IL 299009 A IL299009 A IL 299009A IL 299009 A IL299009 A IL 299009A IL 29900922 A IL29900922 A IL 29900922A IL 299009 A IL299009 A IL 299009A
Authority
IL
Israel
Prior art keywords
myopia
subject
eye
progression
alkaloid
Prior art date
Application number
IL299009A
Other languages
English (en)
Hebrew (he)
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of IL299009A publication Critical patent/IL299009A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL299009A 2020-06-11 2021-06-10 Methods and preparations for the prevention and treatment of myopia (myopia) with berberine, berbridicannane alkaloid, and their derivatives IL299009A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063037918P 2020-06-11 2020-06-11
PCT/US2021/036738 WO2021252717A1 (en) 2020-06-11 2021-06-10 Methods and compositions for preventing and treating myopia with berberine, a berberidaceaen alkaloid, and derivatives thereof

Publications (1)

Publication Number Publication Date
IL299009A true IL299009A (en) 2023-02-01

Family

ID=78845878

Family Applications (1)

Application Number Title Priority Date Filing Date
IL299009A IL299009A (en) 2020-06-11 2021-06-10 Methods and preparations for the prevention and treatment of myopia (myopia) with berberine, berbridicannane alkaloid, and their derivatives

Country Status (7)

Country Link
EP (1) EP4164640A4 (zh)
JP (1) JP2023529945A (zh)
KR (1) KR20230051155A (zh)
CN (1) CN116056727A (zh)
CA (1) CA3182437A1 (zh)
IL (1) IL299009A (zh)
WO (1) WO2021252717A1 (zh)

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1144678A (zh) * 1996-04-25 1997-03-12 白小丁 治疗近视的中成药
MX2007009417A (es) * 2005-02-04 2007-08-17 Univ Auburn Sistema de suministro de farmaco de contacto.
CN101028388B (zh) * 2007-04-04 2011-08-10 西安碑林药业股份有限公司 一种治疗眼疾近视及视疲劳中药制剂的质量检测方法
WO2009143290A2 (en) * 2008-05-20 2009-11-26 Cleveland Biolabs, Inc Inducing cell death by inhibiting adaptive heat shock response
US9827250B2 (en) * 2012-07-31 2017-11-28 Johnson & Johnson Vision Care, Inc. Lens incorporating myopia control optics and muscarinic agents
JP5686454B1 (ja) * 2013-12-12 2015-03-18 株式会社メニコン コンタクトレンズ装着用液剤およびそれを用いたコンタクトレンズの屈折率向上方法
JP2017132764A (ja) * 2016-01-27 2017-08-03 ロート製薬株式会社 シリコーンハイドロゲルカラーコンタクトレンズ用眼科組成物
AU2017342558A1 (en) * 2016-10-14 2019-05-16 Icahn School Of Medicine At Mount Sinai Treatment of immunological disease using berberine nanoparticles
KR20200007769A (ko) * 2017-02-21 2020-01-22 싱가포르 헬스 서비시즈 피티이 엘티디 아트로핀을 포함하는 근시의 발병을 방지 또는 지연하기 위한 조성물 및 방법
CN115645535B (zh) * 2017-03-06 2024-07-09 坪田实验室股份有限公司 小鼠近视诱导模型及用于近视预防/抑制的内质网应激抑制剂
CN107412552B (zh) * 2017-08-07 2020-10-02 秦皇岛康视生物科技有限公司 一种能够治疗儿童近视的护眼液及其制备方法
CN107823451A (zh) * 2017-12-26 2018-03-23 徐艳芹 一种治疗近视眼的外用药物组合物及其制剂的制备方法
CN110433232A (zh) * 2019-09-03 2019-11-12 深圳市中康生物制药有限公司 一种外用的复方黄连液及其制备方法
CN111110737A (zh) * 2020-03-18 2020-05-08 张雪敏 一种纯中药眼药水及其制备方法

Also Published As

Publication number Publication date
EP4164640A1 (en) 2023-04-19
WO2021252717A1 (en) 2021-12-16
CA3182437A1 (en) 2021-12-16
EP4164640A4 (en) 2024-07-17
CN116056727A (zh) 2023-05-02
KR20230051155A (ko) 2023-04-17
JP2023529945A (ja) 2023-07-12

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