IL294615A - קלציום קרבונט אמורפי לטיפול בלוקמיה - Google Patents
קלציום קרבונט אמורפי לטיפול בלוקמיהInfo
- Publication number
- IL294615A IL294615A IL294615A IL29461522A IL294615A IL 294615 A IL294615 A IL 294615A IL 294615 A IL294615 A IL 294615A IL 29461522 A IL29461522 A IL 29461522A IL 294615 A IL294615 A IL 294615A
- Authority
- IL
- Israel
- Prior art keywords
- leukemia
- composition
- acid
- acc
- ceasing
- Prior art date
Links
- 208000032839 leukemia Diseases 0.000 title claims 7
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 title claims 4
- 229910000019 calcium carbonate Inorganic materials 0.000 title claims 2
- 239000000203 mixture Substances 0.000 claims 12
- 229920000388 Polyphosphate Polymers 0.000 claims 4
- 239000001205 polyphosphate Substances 0.000 claims 4
- 235000011176 polyphosphates Nutrition 0.000 claims 4
- 239000003381 stabilizer Substances 0.000 claims 4
- 229940122361 Bisphosphonate Drugs 0.000 claims 3
- 150000004663 bisphosphonates Chemical class 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 150000007524 organic acids Chemical class 0.000 claims 3
- 230000000979 retarding effect Effects 0.000 claims 3
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims 2
- 206010025280 Lymphocytosis Diseases 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 206010000830 Acute leukaemia Diseases 0.000 claims 1
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims 1
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims 1
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims 1
- OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 claims 1
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims 1
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 claims 1
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims 1
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims 1
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims 1
- BZQFBWGGLXLEPQ-UHFFFAOYSA-N O-phosphoryl-L-serine Natural products OC(=O)C(N)COP(O)(O)=O BZQFBWGGLXLEPQ-UHFFFAOYSA-N 0.000 claims 1
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- 229940062527 alendronate Drugs 0.000 claims 1
- 229910001854 alkali hydroxide Inorganic materials 0.000 claims 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical group OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 claims 1
- 208000024207 chronic leukemia Diseases 0.000 claims 1
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims 1
- 229950006137 dexfosfoserine Drugs 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 claims 1
- 235000011180 diphosphates Nutrition 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229960004585 etidronic acid Drugs 0.000 claims 1
- 201000009277 hairy cell leukemia Diseases 0.000 claims 1
- 229940005740 hexametaphosphate Drugs 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- MBKDYNNUVRNNRF-UHFFFAOYSA-N medronic acid Chemical compound OP(O)(=O)CP(O)(O)=O MBKDYNNUVRNNRF-UHFFFAOYSA-N 0.000 claims 1
- 229960003074 medronic acid Drugs 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 150000002894 organic compounds Chemical class 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000004437 phosphorous atom Chemical group 0.000 claims 1
- BZQFBWGGLXLEPQ-REOHCLBHSA-N phosphoserine Chemical compound OC(=O)[C@@H](N)COP(O)(O)=O BZQFBWGGLXLEPQ-REOHCLBHSA-N 0.000 claims 1
- USRGIUJOYOXOQJ-GBXIJSLDSA-N phosphothreonine Chemical compound OP(=O)(O)O[C@H](C)[C@H](N)C(O)=O USRGIUJOYOXOQJ-GBXIJSLDSA-N 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
- 239000001226 triphosphate Substances 0.000 claims 1
- 235000011178 triphosphate Nutrition 0.000 claims 1
- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 claims 1
- XRASPMIURGNCCH-UHFFFAOYSA-N zoledronic acid Chemical compound OP(=O)(O)C(P(O)(O)=O)(O)CN1C=CN=C1 XRASPMIURGNCCH-UHFFFAOYSA-N 0.000 claims 1
- 229960004276 zoledronic acid Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/015—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662412300P | 2016-10-25 | 2016-10-25 | |
| PCT/IL2017/051160 WO2018078616A1 (en) | 2016-10-25 | 2017-10-23 | Amorphous calcium carbonate for treating a leukemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL294615A true IL294615A (he) | 2022-09-01 |
Family
ID=62024452
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL294615A IL294615A (he) | 2016-10-25 | 2017-10-23 | קלציום קרבונט אמורפי לטיפול בלוקמיה |
| IL266149A IL266149B (he) | 2016-10-25 | 2017-10-23 | קלציום קרבונט אמורפי לטיפול בלוקמיה |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL266149A IL266149B (he) | 2016-10-25 | 2017-10-23 | קלציום קרבונט אמורפי לטיפול בלוקמיה |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11052108B2 (he) |
| EP (1) | EP3532074B1 (he) |
| JP (1) | JP7152785B2 (he) |
| KR (1) | KR102531595B1 (he) |
| CN (2) | CN114948992A (he) |
| AU (1) | AU2017349921B2 (he) |
| IL (2) | IL294615A (he) |
| WO (1) | WO2018078616A1 (he) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL289237B2 (he) | 2019-07-23 | 2026-03-01 | Amorphical Ltd | קלציום קרבונט אמורפי לשיפור ביצועי ספורטאים |
| WO2021181372A1 (en) * | 2020-03-11 | 2021-09-16 | Amorphical Ltd. | Amorphous calcium carbonate for treatment of acidosis |
Family Cites Families (52)
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|---|---|---|---|---|
| US4237147A (en) | 1974-01-04 | 1980-12-02 | Monsanto Company | Stabilized amorphous calcium carbonate |
| US4199496A (en) | 1974-09-05 | 1980-04-22 | Johnson Edwin L | Process for the recovery of chemicals from the shells of crustacea |
| EP0052677B1 (en) | 1980-11-21 | 1985-01-09 | Monsanto Company | Concentrates for the preparation of carbonated beverages |
| US4964894A (en) | 1986-03-31 | 1990-10-23 | Freepons Donald E | Plant growth regulators derived from chitin |
| DE3875867T2 (de) | 1987-08-28 | 1993-04-01 | Norwich Eaton Pharma | Kalziumzusaetze. |
| GB2217988B (en) | 1988-04-11 | 1992-04-01 | Gould Leonard W | Regimen for increasing bone density in humans |
| DE3853422T2 (de) | 1988-06-09 | 1995-10-26 | Innogenetics Nv | HIV-3-Retrovirus und seine Verwendung. |
| US5886012A (en) | 1989-03-22 | 1999-03-23 | Peter K. T. Pang | Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers |
| US5037639A (en) | 1989-05-24 | 1991-08-06 | American Dental Association Health Foundation | Methods and compositions for mineralizing calcified tissues |
| US6348571B1 (en) | 1994-09-12 | 2002-02-19 | Northwestern University | Corticotropin release inhibiting factor and methods of using same |
| JPH099871A (ja) | 1995-07-03 | 1997-01-14 | Kita Nippon Shokuhin Kk | 菓 子 |
| WO1997024069A1 (en) | 1995-12-26 | 1997-07-10 | Holomed Aps | A method and system for generating an x-ray image |
| JPH10236957A (ja) | 1997-02-24 | 1998-09-08 | Bankaku Souhonpo:Kk | 骨粗鬆症の改善剤 |
| US20060165784A1 (en) | 1997-05-06 | 2006-07-27 | Zhao Jin R | Calcium supplement |
| SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
| US6569472B1 (en) | 2000-09-01 | 2003-05-27 | Wm. Wrigley Jr. Company | Coated chewing gum products containing antacid and method of making |
| US20030077604A1 (en) | 2000-10-27 | 2003-04-24 | Yongming Sun | Compositions and methods relating to breast specific genes and proteins |
| JP2002205947A (ja) | 2000-12-11 | 2002-07-23 | Chafflose Corporation | 水虫治療薬 |
| EP1416916B1 (en) | 2001-08-16 | 2007-10-17 | Cmp Therapeutics Limited | Chitin microparticles and their medical uses |
| JP2003292453A (ja) | 2002-04-02 | 2003-10-15 | Asahi Kasei Corp | 骨疾患治療用医薬複合剤 |
| JP2004081739A (ja) | 2002-08-29 | 2004-03-18 | Mitsuru Akashi | ハイドロキシアパタイト−ポリマー複合材料の止血用組成物 |
| KR20020082813A (ko) | 2002-09-06 | 2002-10-31 | 한국지질자원연구원 | 에탄올-에틸렌 글리콜계에서의 탄산화 반응을 이용하여제조된 비정질 탄산칼슘의 후처리 방법 |
| WO2005025581A1 (fr) | 2003-09-17 | 2005-03-24 | Third Military Medical University, Chinese People's Liberation Army, P.R. Of China | Utilisation de la n-acetyl-d-aminoglycosamine pour la preparation de medicaments de traitement du cancer et des metastases |
| GB0324918D0 (en) | 2003-10-24 | 2003-11-26 | Glaxo Group Ltd | Composition |
| KR100561231B1 (ko) | 2004-05-18 | 2006-03-15 | 한국지질자원연구원 | 표면개질에 의한 비정질 탄산칼슘 제조방법 |
| CA2567972C (en) | 2004-05-26 | 2015-07-28 | Ben-Gurion University Of The Negev Research And Development Authority | Orally-administrable compositions comprising stable amorphous calcium carbonate |
| WO2006043966A2 (en) | 2004-10-15 | 2006-04-27 | University Of Tennessee Research Foundation | Methods for inducing apoptosis in adipocytes |
| SG158153A1 (en) | 2004-12-21 | 2010-01-29 | Musc Found For Res Dev | Compositions and methods for promoting wound healing and tissue regeneration |
| CN101090949B (zh) | 2004-12-22 | 2013-06-05 | 索尔维公司 | 碱土金属碳酸盐的耐酸粒子 |
| DE102005047807A1 (de) | 2005-06-04 | 2006-12-07 | Solvay Infra Bad Hönningen GmbH | Modifizierte Nanopartikel |
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| IL178495A (he) * | 2006-10-05 | 2014-12-31 | Univ Ben Gurion | שימוש במרכיבי גסטרולית של סרטן או בתערובת מלאכותית המכילה סידן פחמתי, כיטין ופוליפפטיד להכנת תרופה לטיפול במצבים הקשורים למטבוליזם של סידן או העברת אותות על ידי סידן |
| PL2211873T3 (pl) | 2007-10-22 | 2013-01-31 | Amorphical Ltd | Stabilny amorficzny węglan wapnia wchodzący w skład fosforylowanych aminokwasów |
| WO2009087553A1 (en) | 2008-01-02 | 2009-07-16 | Aurobindo Pharma Limited | Kits for administering bisphosphonates |
| CN101314031A (zh) | 2008-07-14 | 2008-12-03 | 王冰 | 一种改善骨营养的制剂 |
| EP2334292B1 (en) | 2008-10-17 | 2019-05-08 | Fresenius Medical Care Holdings, Inc. | Method of determining a phosphorus binder dosage for a dialysis patient |
| WO2010093285A1 (en) | 2009-02-12 | 2010-08-19 | Aduro Material Ab | Composition comprising biodegradable carrier for controlled drug delivery |
| CN101580260B (zh) | 2009-05-31 | 2011-04-27 | 河南大学 | 一种微乳液法制备无定形碳酸钙的方法 |
| EP2598579B1 (de) | 2010-07-30 | 2024-09-11 | Schaefer Kalk GmbH & Co. KG | Kugelförmige, amorphe calciumcarbonat-teilchen |
| CN103200938B (zh) | 2010-08-30 | 2018-07-31 | 普马特里克斯营业公司 | 干燥粉末配方及用于治疗肺部疾病的方法 |
| CN102085356B (zh) | 2010-12-28 | 2013-02-27 | 北京同仁堂健康药业股份有限公司 | 一种用于增加骨密度的组合物及其制备方法 |
| EP2702009A4 (en) | 2011-04-28 | 2015-02-18 | Calera Corp | METHODS AND COMPOSITIONS USING CALCIUM CARBONATE AND STABILIZER |
| EP2790710B1 (en) * | 2011-12-13 | 2020-08-26 | Amorphical Ltd. | Amorphous calcium carbonate for the treatment of calcium malabsorption and metabolic bone disorders |
| WO2014024191A1 (en) | 2012-08-07 | 2014-02-13 | Amorphical Ltd. | Method for producing stabilized amorphous calcium carbonate |
| JP2016507553A (ja) | 2013-02-11 | 2016-03-10 | アモーフィカル リミテッド． | 骨成長を促進する非晶質炭酸カルシウム |
| CN103663532B (zh) | 2013-12-21 | 2015-10-28 | 中国科学院上海硅酸盐研究所 | 一种制备无定形碳酸钙纳米球的方法 |
| EP3174409A4 (en) | 2014-07-31 | 2018-01-17 | Amorphical Ltd. | Encapsulated amorphous calcium carbonate compositions |
| HK1253702A1 (zh) | 2015-06-04 | 2019-06-28 | 艾玛菲克有限公司 | 用聚磷酸/聚磷酸酯/聚磷酸盐或双膦酸/双膦酸酯/双膦酸盐稳定的无定形碳酸钙 |
| JP6873389B2 (ja) | 2016-01-18 | 2021-05-19 | アモーフィカル リミテッド． | 神経学的、筋肉、および不妊の疾患または症状の治療のための安定化無定形炭酸カルシウム |
| ES3052833T3 (en) | 2016-01-18 | 2026-01-15 | Amorphical Ltd | Stabilized amorphous calcium carbonate as a supplement for cell culture media |
-
2017
- 2017-10-23 JP JP2019521063A patent/JP7152785B2/ja active Active
- 2017-10-23 EP EP17863623.9A patent/EP3532074B1/en active Active
- 2017-10-23 CN CN202210530126.4A patent/CN114948992A/zh active Pending
- 2017-10-23 KR KR1020197014131A patent/KR102531595B1/ko active Active
- 2017-10-23 IL IL294615A patent/IL294615A/he unknown
- 2017-10-23 AU AU2017349921A patent/AU2017349921B2/en active Active
- 2017-10-23 IL IL266149A patent/IL266149B/he unknown
- 2017-10-23 CN CN201780080064.9A patent/CN110121351A/zh active Pending
- 2017-10-23 WO PCT/IL2017/051160 patent/WO2018078616A1/en not_active Ceased
- 2017-10-23 US US16/343,463 patent/US11052108B2/en active Active
-
2021
- 2021-06-14 US US17/346,975 patent/US20210299165A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL266149B (he) | 2022-08-01 |
| CN114948992A (zh) | 2022-08-30 |
| CN110121351A (zh) | 2019-08-13 |
| US20190262391A1 (en) | 2019-08-29 |
| KR20190073448A (ko) | 2019-06-26 |
| US11052108B2 (en) | 2021-07-06 |
| AU2017349921B2 (en) | 2023-06-15 |
| JP2019532086A (ja) | 2019-11-07 |
| IL266149A (he) | 2019-06-30 |
| JP7152785B2 (ja) | 2022-10-13 |
| EP3532074C0 (en) | 2023-08-23 |
| WO2018078616A1 (en) | 2018-05-03 |
| EP3532074A1 (en) | 2019-09-04 |
| US20210299165A1 (en) | 2021-09-30 |
| EP3532074A4 (en) | 2020-07-08 |
| KR102531595B1 (ko) | 2023-05-11 |
| EP3532074B1 (en) | 2023-08-23 |
| AU2017349921A1 (en) | 2019-06-06 |
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