IL290122B2 - Clotting template, kit and method for making a blood clot - Google Patents

Clotting template, kit and method for making a blood clot

Info

Publication number
IL290122B2
IL290122B2 IL290122A IL29012222A IL290122B2 IL 290122 B2 IL290122 B2 IL 290122B2 IL 290122 A IL290122 A IL 290122A IL 29012222 A IL29012222 A IL 29012222A IL 290122 B2 IL290122 B2 IL 290122B2
Authority
IL
Israel
Prior art keywords
powder
whole blood
particle
size distribution
calcium gluconate
Prior art date
Application number
IL290122A
Other languages
English (en)
Hebrew (he)
Other versions
IL290122B1 (en
IL290122A (cg-RX-API-DMAC7.html
Original Assignee
Reddress Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reddress Ltd filed Critical Reddress Ltd
Priority to IL290122A priority Critical patent/IL290122B2/en
Publication of IL290122A publication Critical patent/IL290122A/en
Priority to AU2023214201A priority patent/AU2023214201A1/en
Priority to EP23705316.0A priority patent/EP4447889A1/en
Priority to CN202380018300.XA priority patent/CN118613239A/zh
Priority to JP2024539932A priority patent/JP2025504710A/ja
Priority to PCT/IL2023/050083 priority patent/WO2023144818A1/en
Priority to MX2024009036A priority patent/MX2024009036A/es
Priority to KR1020247024731A priority patent/KR20240144143A/ko
Priority to CA3242778A priority patent/CA3242778A1/en
Publication of IL290122B1 publication Critical patent/IL290122B1/en
Publication of IL290122B2 publication Critical patent/IL290122B2/en
Priority to US18/783,156 priority patent/US12397018B2/en
Priority to ZA2024/06452A priority patent/ZA202406452B/en
Priority to US18/983,077 priority patent/US20250114399A1/en
Priority to US19/032,762 priority patent/US12599629B2/en
Priority to US19/058,528 priority patent/US12364713B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/00987Apparatus or processes for manufacturing non-adhesive dressings or bandages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Manufacturing & Machinery (AREA)
  • Botany (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL290122A 2022-01-25 2022-01-25 Clotting template, kit and method for making a blood clot IL290122B2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IL290122A IL290122B2 (en) 2022-01-25 2022-01-25 Clotting template, kit and method for making a blood clot
EP23705316.0A EP4447889A1 (en) 2022-01-25 2023-01-25 A coagulation mold, a kit and a method for preparing a coagulated blood mass
MX2024009036A MX2024009036A (es) 2022-01-25 2023-01-25 Un molde de coagulacion, un kit y un metodo para preparar una masa sanguinea coagulada.
CA3242778A CA3242778A1 (en) 2022-01-25 2023-01-25 A coagulation mold, a kit and a method for preparing a coagulated blood mass
CN202380018300.XA CN118613239A (zh) 2022-01-25 2023-01-25 用于制备凝血块的凝血模具、试剂盒和方法
JP2024539932A JP2025504710A (ja) 2022-01-25 2023-01-25 凝血塊を調製するための凝血型、キット及び方法
PCT/IL2023/050083 WO2023144818A1 (en) 2022-01-25 2023-01-25 A coagulation mold, a kit and a method for preparing a coagulated blood mass
AU2023214201A AU2023214201A1 (en) 2022-01-25 2023-01-25 A coagulation mold, a kit and a method for preparing a coagulated blood mass
KR1020247024731A KR20240144143A (ko) 2022-01-25 2023-01-25 응고된 혈액 덩어리를 제조하기 위한 응고 몰드, 키트 및 방법
US18/783,156 US12397018B2 (en) 2022-01-25 2024-07-24 Coagulation mold, a kit and a method for preparing a coagulated blood mass
ZA2024/06452A ZA202406452B (en) 2022-01-25 2024-08-22 A coagulation mold, a kit and a method for preparing a coagulated blood mass
US18/983,077 US20250114399A1 (en) 2022-01-25 2024-12-16 Coagulation mold, a kit and a method for preparing a coagulated blood mass
US19/032,762 US12599629B2 (en) 2022-01-25 2025-01-21 Coagulation mold, a kit and a method for preparing a coagulated blood mass
US19/058,528 US12364713B2 (en) 2022-01-25 2025-02-20 Coagulation mold, a kit and a method for preparing a coagulated blood mass

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL290122A IL290122B2 (en) 2022-01-25 2022-01-25 Clotting template, kit and method for making a blood clot

Publications (3)

Publication Number Publication Date
IL290122A IL290122A (cg-RX-API-DMAC7.html) 2022-03-01
IL290122B1 IL290122B1 (en) 2023-04-01
IL290122B2 true IL290122B2 (en) 2023-08-01

Family

ID=85238983

Family Applications (1)

Application Number Title Priority Date Filing Date
IL290122A IL290122B2 (en) 2022-01-25 2022-01-25 Clotting template, kit and method for making a blood clot

Country Status (11)

Country Link
US (4) US12397018B2 (cg-RX-API-DMAC7.html)
EP (1) EP4447889A1 (cg-RX-API-DMAC7.html)
JP (1) JP2025504710A (cg-RX-API-DMAC7.html)
KR (1) KR20240144143A (cg-RX-API-DMAC7.html)
CN (1) CN118613239A (cg-RX-API-DMAC7.html)
AU (1) AU2023214201A1 (cg-RX-API-DMAC7.html)
CA (1) CA3242778A1 (cg-RX-API-DMAC7.html)
IL (1) IL290122B2 (cg-RX-API-DMAC7.html)
MX (1) MX2024009036A (cg-RX-API-DMAC7.html)
WO (1) WO2023144818A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA202406452B (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025243305A1 (en) 2024-05-23 2025-11-27 Reddress Ltd. Controlled drug delivery
EP4686486A1 (en) * 2024-07-30 2026-02-04 Paul Hartmann AG Gel composition comprising whole blood

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10111979B2 (en) * 2009-01-27 2018-10-30 Reddress Ltd. Wound dressings, methods and apparatus for making same and storage and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL254636A0 (en) 2017-09-24 2017-11-30 Reddress Ltd System and method for preparing a wound dressing
IL257229B (en) 2018-01-30 2022-07-01 Reddress Ltd Blood applicator for tissue treatment

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10111979B2 (en) * 2009-01-27 2018-10-30 Reddress Ltd. Wound dressings, methods and apparatus for making same and storage and use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KUSHNIR, IGAL ET AL., EFFICACY AND SAFETY OF A NOVEL AUTOLOGOUS WOUND MATRIX IN THE MANAGEMENT OF COMPLICATED, CHRONIC WOUNDS: A PILOT STUDY., 31 December 2016 (2016-12-31) *

Also Published As

Publication number Publication date
CN118613239A (zh) 2024-09-06
EP4447889A1 (en) 2024-10-23
US12397018B2 (en) 2025-08-26
WO2023144818A1 (en) 2023-08-03
US20250161353A1 (en) 2025-05-22
AU2023214201A2 (en) 2024-08-15
MX2024009036A (es) 2024-08-06
US20250114399A1 (en) 2025-04-10
KR20240144143A (ko) 2024-10-02
IL290122B1 (en) 2023-04-01
US20240374636A1 (en) 2024-11-14
US20250186488A1 (en) 2025-06-12
IL290122A (cg-RX-API-DMAC7.html) 2022-03-01
AU2023214201A1 (en) 2024-08-08
ZA202406452B (en) 2025-04-30
JP2025504710A (ja) 2025-02-17
US12364713B2 (en) 2025-07-22
US12599629B2 (en) 2026-04-14
CA3242778A1 (en) 2023-08-03

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