IL287573A - Methods and compositions for the treatment of chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues - Google Patents
Methods and compositions for the treatment of chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissuesInfo
- Publication number
- IL287573A IL287573A IL287573A IL28757321A IL287573A IL 287573 A IL287573 A IL 287573A IL 287573 A IL287573 A IL 287573A IL 28757321 A IL28757321 A IL 28757321A IL 287573 A IL287573 A IL 287573A
- Authority
- IL
- Israel
- Prior art keywords
- metaplasia
- dysplasia
- cancers
- compositions
- methods
- Prior art date
Links
- 206010058314 Dysplasia Diseases 0.000 title 1
- 206010054949 Metaplasia Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 208000027418 Wounds and injury Diseases 0.000 title 1
- 230000001684 chronic effect Effects 0.000 title 1
- 230000006378 damage Effects 0.000 title 1
- 210000000981 epithelium Anatomy 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 208000014674 injury Diseases 0.000 title 1
- 230000015689 metaplastic ossification Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
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- Developmental Biology & Embryology (AREA)
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- Molecular Biology (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962839152P | 2019-04-26 | 2019-04-26 | |
| US201962924978P | 2019-10-23 | 2019-10-23 | |
| PCT/US2020/029933 WO2020219963A1 (en) | 2019-04-26 | 2020-04-24 | Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
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| EP4121111A4 (en) * | 2020-03-20 | 2024-05-15 | University of Houston System | METHODS AND COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY AND FIBROTIC LUNG DISEASES |
| JP2024504378A (ja) * | 2021-01-25 | 2024-01-31 | アトス セラピューティクス,インコーポレイテッド | トリアジン化合物ならびにこれを作製する方法および使用する方法 |
| MX2024004848A (es) * | 2021-10-22 | 2024-07-15 | Univ Houston System | Metodos y composiciones para el tratamiento de lesiones inflamatorias cronicas, metaplasias, displasia y canceres de tejidos epiteliales. |
| WO2025212580A1 (en) * | 2024-04-01 | 2025-10-09 | Xdc Precision Therapeutics Llc | Antibody-kras binder conjugates, pharmaceutical compositions, and therapeutic applications |
| WO2025253352A1 (en) * | 2024-06-07 | 2025-12-11 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet) | Methods for promoting hepatic regeneration |
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| CN114007671B (zh) | 2024-06-14 |
| CN114007671A (zh) | 2022-02-01 |
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