IL275340A - Peptides and other active compounds to treat pain and increase pain sensitivity - Google Patents
Peptides and other active compounds to treat pain and increase pain sensitivityInfo
- Publication number
- IL275340A IL275340A IL275340A IL27534020A IL275340A IL 275340 A IL275340 A IL 275340A IL 275340 A IL275340 A IL 275340A IL 27534020 A IL27534020 A IL 27534020A IL 275340 A IL275340 A IL 275340A
- Authority
- IL
- Israel
- Prior art keywords
- pain
- peptides
- agents
- increasing
- sensitivity
- Prior art date
Links
- 230000008533 pain sensitivity Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/04—Phosphotransferases with a phosphate group as acceptor (2.7.4)
- C12Y207/04008—Guanylate kinase (2.7.4.8)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762598067P | 2017-12-13 | 2017-12-13 | |
| PCT/US2018/065545 WO2019118779A2 (en) | 2017-12-13 | 2018-12-13 | Peptides and other agents for treating pain and increasing pain sensitivity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL275340A true IL275340A (en) | 2020-07-30 |
Family
ID=66820711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL275340A IL275340A (en) | 2017-12-13 | 2020-06-14 | Peptides and other active compounds to treat pain and increase pain sensitivity |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11535649B2 (https=) |
| EP (1) | EP3723781B1 (https=) |
| JP (2) | JP2021506794A (https=) |
| CN (1) | CN111712252A (https=) |
| AU (1) | AU2018383669B2 (https=) |
| CA (1) | CA3085576A1 (https=) |
| IL (1) | IL275340A (https=) |
| WO (1) | WO2019118779A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3085576A1 (en) * | 2017-12-13 | 2019-06-20 | The Research Foundation For The State University Of New York | Peptides and other agents for treating pain and increasing pain sensitivity |
| BR112022006862A2 (pt) * | 2019-10-10 | 2022-07-05 | Univ New York State Res Found | Peptídeo, composição, e, método para tratar dor ou aumentar a sensibilidade à dor |
| US20240165247A1 (en) * | 2021-03-17 | 2024-05-23 | Jiangyin Usun Pharmaceutical Co., Ltd. | New peptide conjugates |
| WO2025102083A1 (en) * | 2023-11-12 | 2025-05-15 | The Research Foundation For The State University Of New York | Compositions and methods for treating pain or for increasing pain sensitivity |
| WO2025123001A1 (en) * | 2023-12-08 | 2025-06-12 | Washington University | Targeted protein degradation compositions and methods of use thereof for pain control |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6187533B1 (en) * | 1996-09-10 | 2001-02-13 | Arch Development Corporation | Mutations in the diabetes susceptibility genes hepatocyte nuclear factor (HNF) 1 alpha (α), HNF1β and HNF4α |
| SI2168984T1 (sl) * | 1999-03-25 | 2012-12-31 | Abbott Gmbh & Co. Kg | Človeška protitelesa za vezavo IL-12 in postopki izdelave |
| EP1252330A2 (en) | 1999-11-26 | 2002-10-30 | McGill University | Loci for idiopathic generalized epilepsy, mutations thereof and method using same to assess, diagnose, prognose or treat epilepsy |
| US20030216310A1 (en) | 2001-05-25 | 2003-11-20 | Thornton Michael B. | Transporters and ion channels |
| US20090087436A1 (en) | 2001-07-13 | 2009-04-02 | Myriad Genetics, Incorporated | Compositions and methods for treating diseases |
| WO2004045535A2 (en) | 2002-11-14 | 2004-06-03 | Arbor Vita Corporation | Molecular interactions in neurons |
| EP1438584A4 (en) * | 2001-10-01 | 2006-12-27 | Buck Inst | TARGET-ASSISTED ITERATIVE SCREENING (TAIS), NEW SCREEN FORMAT FOR LARGE MOLECULAR REPERTOIRES |
| WO2003087768A2 (en) | 2002-04-12 | 2003-10-23 | Mitokor | Targets for therapeutic intervention identified in the mitochondrial proteome |
| US20040180848A1 (en) | 2003-03-10 | 2004-09-16 | Fesik Stephen W. | Method of killing cancer cells |
| WO2005059101A2 (en) | 2003-12-12 | 2005-06-30 | Wyeth | Novel sodium channel |
| EP1709084A4 (en) | 2003-12-23 | 2008-05-28 | Nono Inc | POLYPEPTIDES FOR MODULATING BINDING OF TRP-CHANNEL PROTEINS AND TRP-ASSOCIATED PROTEINS |
| WO2005118614A1 (en) * | 2004-04-08 | 2005-12-15 | Avigen, Inc. | Methods and compositions for treating neuropathic pain |
| US7485468B2 (en) | 2004-10-15 | 2009-02-03 | Galapagos Bv | Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases |
| US20100088778A1 (en) | 2005-06-16 | 2010-04-08 | John Charles Mulley | Methods of Treatment, and Diagnosis of Epilepsy by Detecting Mutations in the SCN1A Gene |
| JP2010529966A (ja) | 2007-06-08 | 2010-09-02 | アシュラジェン インコーポレイテッド | 治療的介入の標的としてmiR−34によって調節される遺伝子および経路 |
| WO2009006555A2 (en) | 2007-07-02 | 2009-01-08 | Yu, Ming | Methods, composition, targets for combinational cancer treatments |
| US20090118301A1 (en) | 2007-11-02 | 2009-05-07 | Arbor Vita Corporation | Compositions and Methods for Treating Cancer |
| DK2307035T3 (da) | 2008-05-16 | 2014-01-20 | Nono Inc | Anvendelse af en PSD-95 inhibitor ved behandlingen af epilepsi |
| JP2012503619A (ja) | 2008-09-26 | 2012-02-09 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Hcv感染に対する抗ウイルス治療のための標的としての宿主細胞キナーゼ |
| EP2275545A1 (en) | 2009-07-16 | 2011-01-19 | Julius-Maximilians-Universität Würzburg | Use of microRNA-24 and/or its targets for the treatment and prevention of ischemia and induction of angiogenesis |
| EP2478002B1 (en) * | 2009-09-18 | 2015-02-25 | University Of Houston | Small peptide modulators of potassium channel trafficking |
| WO2012004664A2 (en) * | 2010-07-07 | 2012-01-12 | Purdue Pharma L.P. | Analogs of sodium channel peptide toxin |
| CN103068982B (zh) | 2010-07-14 | 2017-06-09 | 库尔纳公司 | 通过抑制盘状大同系物(dlg)的天然反义转录物而治疗dlg相关疾病 |
| EP2616094B1 (en) | 2010-08-12 | 2017-11-08 | NoNO Inc. | Treatment of penetrative injury to the brain |
| WO2012135666A1 (en) | 2011-04-01 | 2012-10-04 | University Of Louisiana At Monroe | Inhibitors of metastasis, methods of generating such inhibitors and their therapeutic applications |
| EP2773366B1 (en) * | 2011-11-04 | 2017-03-01 | Lipotec, S.A. | Peptides which inhibit activated receptors and their use in cosmetic or pharmaceutical compositions |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| JP2019512015A (ja) * | 2016-02-26 | 2019-05-09 | ザ・ジョンズ・ホプキンス・ユニバーシティ | 機械的刺激による痛みに関連する電位依存性ナトリウム・チャネルNav1.1に対する調節薬 |
| CA3085576A1 (en) * | 2017-12-13 | 2019-06-20 | The Research Foundation For The State University Of New York | Peptides and other agents for treating pain and increasing pain sensitivity |
-
2018
- 2018-12-13 CA CA3085576A patent/CA3085576A1/en active Pending
- 2018-12-13 EP EP18887737.7A patent/EP3723781B1/en active Active
- 2018-12-13 JP JP2020532629A patent/JP2021506794A/ja active Pending
- 2018-12-13 CN CN201880089341.7A patent/CN111712252A/zh active Pending
- 2018-12-13 AU AU2018383669A patent/AU2018383669B2/en active Active
- 2018-12-13 WO PCT/US2018/065545 patent/WO2019118779A2/en not_active Ceased
- 2018-12-13 US US16/771,204 patent/US11535649B2/en active Active
-
2020
- 2020-06-14 IL IL275340A patent/IL275340A/en unknown
-
2022
- 2022-09-29 US US17/956,031 patent/US12077610B2/en active Active
-
2023
- 2023-11-17 JP JP2023195583A patent/JP2024026109A/ja active Pending
-
2024
- 2024-08-28 US US18/818,129 patent/US20250154199A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019118779A3 (en) | 2019-07-25 |
| US20230046305A1 (en) | 2023-02-16 |
| US11535649B2 (en) | 2022-12-27 |
| JP2021506794A (ja) | 2021-02-22 |
| US20200369726A1 (en) | 2020-11-26 |
| EP3723781B1 (en) | 2024-12-11 |
| AU2018383669A1 (en) | 2020-07-02 |
| EP3723781A4 (en) | 2021-07-21 |
| AU2018383669B2 (en) | 2023-05-18 |
| CN111712252A (zh) | 2020-09-25 |
| US12077610B2 (en) | 2024-09-03 |
| JP2024026109A (ja) | 2024-02-28 |
| WO2019118779A2 (en) | 2019-06-20 |
| US20250154199A1 (en) | 2025-05-15 |
| EP3723781A2 (en) | 2020-10-21 |
| CA3085576A1 (en) | 2019-06-20 |
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