IL27321A - 3, 4 - ציס - 4 - אריל - איזופלאבאנים והכנתם - Google Patents
3, 4 - ציס - 4 - אריל - איזופלאבאנים והכנתםInfo
- Publication number
- IL27321A IL27321A IL27321A IL2732167A IL27321A IL 27321 A IL27321 A IL 27321A IL 27321 A IL27321 A IL 27321A IL 2732167 A IL2732167 A IL 2732167A IL 27321 A IL27321 A IL 27321A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- acid
- physiologically acceptable
- alkoxy
- quaternary ammonium
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEM0068414 | 1966-02-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL27321A true IL27321A (he) | 1970-09-17 |
Family
ID=7312594
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL27321A IL27321A (he) | 1966-02-16 | 1967-01-25 | 3, 4 - ציס - 4 - אריל - איזופלאבאנים והכנתם |
Country Status (11)
Country | Link |
---|---|
US (1) | US3535344A (he) |
BE (1) | BE694025A (he) |
CH (1) | CH494222A (he) |
DE (1) | DE1543749A1 (he) |
DK (1) | DK118611B (he) |
ES (1) | ES336869A1 (he) |
FR (1) | FR6192M (he) |
GB (1) | GB1103094A (he) |
IL (1) | IL27321A (he) |
NL (1) | NL6702140A (he) |
SE (1) | SE328301B (he) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4053626A (en) * | 1973-03-13 | 1977-10-11 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Cholesterol level-lowering phenoxyacetic acids |
EP0656786B2 (en) | 1992-05-19 | 2014-04-23 | Novogen Research Pty Ltd | Use of isoflavone phyto-oestrogen extracts of soy or clover |
US5446061A (en) * | 1993-11-05 | 1995-08-29 | Eli Lilly And Company | Methods for lowering serum cholesterol |
US5407955A (en) * | 1994-02-18 | 1995-04-18 | Eli Lilly And Company | Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease |
US5446071A (en) * | 1994-11-18 | 1995-08-29 | Eli Lilly And Company | Methods for lowering serum cholesterol |
HUP9800521A3 (en) * | 1995-01-13 | 1999-12-28 | Novo Nordisk As | Use of 3,4-diphenyl chromans for the manufacture of a pharmaceutical composition for the treatment or propylaxis of hyperlipoproteinaemia, hypertriglyceridaemia, hyperlipidaemia or hypercholesterolaemia or arteriosclerosis |
AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
JP2001502705A (ja) * | 1996-10-28 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | エストロゲン関係疾患または症候群の予防または治療において有用な新規なシス―3,4―クロマン誘導体 |
US5985306A (en) * | 1996-10-28 | 1999-11-16 | Novo Nordisk A/S | (+)-enantiomers of cis-3,4-chroman derivatives useful in prevention or treatment of estrogen diseases or syndromes |
CA2270056A1 (en) * | 1996-10-28 | 1998-05-07 | Poul Jacobsen | Novel cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
WO1998018772A1 (en) * | 1996-10-28 | 1998-05-07 | Novo Nordisk A/S | NOVEL cis-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES |
US5958967A (en) * | 1996-10-28 | 1999-09-28 | Novo Nordisk A/S | Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
ATE231141T1 (de) * | 1996-10-28 | 2003-02-15 | Novo Nordisk As | (-)-enantiomere von cis-3,4-chromanderivaten zur vorbeugung oder behandlungvon oestrogenbezogenen krankheiten oder syndromen |
EP0937059A1 (en) * | 1996-10-28 | 1999-08-25 | Novo Nordisk A/S | NOVEL $i(TRANS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES |
ZA979644B (en) * | 1996-10-28 | 1998-04-28 | Novo Nordisk As | Heterocyclic compounds, compositions and uses. |
US5994390A (en) * | 1996-10-28 | 1999-11-30 | Novo Nordisk | Trans-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
EP0937060B1 (en) * | 1996-10-28 | 2002-12-11 | Novo Nordisk A/S | Cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
US6316494B1 (en) | 1996-10-28 | 2001-11-13 | Novo Nordisk A/S | cis3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
US5919817A (en) * | 1996-10-28 | 1999-07-06 | Novo Nordisk A/S | Cis-3, 4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
US6043269A (en) * | 1996-10-28 | 2000-03-28 | Novo Nordisk A/S | cis-3,4-chroman derivatives useful in the prevention or treatment of estrogen related diseases or syndromes |
JP2001502711A (ja) * | 1996-10-28 | 2001-02-27 | ノボ ノルディスク アクティーゼルスカブ | エストロゲン関連疾患又は症候群の予防又は治療において有用な新規のシス―3、4―クロマン誘導体 |
EP0937061A1 (en) * | 1996-10-28 | 1999-08-25 | Novo Nordisk A/S | NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES |
US6146668A (en) | 1997-04-28 | 2000-11-14 | Novogen, Inc. | Preparation of isoflavones from legumes |
EP0979074A4 (en) * | 1997-05-01 | 2003-07-09 | Novogen Inc | TREATMENT OR PREVENTION CLIMATE ACTION SYMPTOMS AND OSTEOPOROSIS |
AUPP112497A0 (en) * | 1997-12-24 | 1998-01-22 | Novogen Research Pty Ltd | Compositions and method for protecting skin from UV induced immunosupression and skin damage |
AUPP260798A0 (en) * | 1998-03-26 | 1998-04-23 | Novogen Research Pty Ltd | Treatment of medical related conditions with isoflavone containing extracts of clover |
KR20000001793A (ko) | 1998-06-13 | 2000-01-15 | 이경하 | 신규한 벤조피란 또는 티오벤조피란 유도체 |
AUPP868599A0 (en) * | 1999-02-15 | 1999-03-11 | Novogen Research Pty Ltd | Production of isoflavone derivatives |
AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
US20090233999A1 (en) * | 1999-09-06 | 2009-09-17 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
JP4896335B2 (ja) * | 2000-03-01 | 2012-03-14 | ナームローゼ・フエンノートチヤツプ・オルガノン | エストロゲン化合物としてのクロマン誘導体 |
AUPR363301A0 (en) * | 2001-03-08 | 2001-04-05 | Novogen Research Pty Ltd | Dimeric isoflavones |
US20050119301A1 (en) * | 2001-03-16 | 2005-06-02 | Alan Husband | Treatment of restenosis |
CA2546643A1 (en) * | 2003-11-18 | 2005-06-02 | Novogen Research Pty Ltd | Isoflavonoid prodrugs, compositions thereof and therapeutic methods involving same |
AU2004290613B2 (en) * | 2003-11-18 | 2010-03-25 | Novogen Research Pty Ltd | Isoflavonoid prodrugs, compositions thereof and therapeutic methods involving same |
EP2407462B1 (en) | 2004-09-21 | 2014-07-30 | Marshall Edwards, Inc. | Substituted chroman derivatives, medicaments and use in therapy |
US8080675B2 (en) * | 2004-09-21 | 2011-12-20 | Marshall Edwards, Inc. | Chroman derivatives, medicaments and use in therapy |
CA2816322A1 (en) | 2010-11-01 | 2012-05-10 | Marshall Edwards, Inc. | Isoflavonoid compositions and methods for the treatment of cancer |
CA2974123C (en) | 2015-02-02 | 2023-08-01 | Mei Pharma, Inc. | Combination of benzopyran derivative and glycolytic inhibitors for cancer therapy |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3340276A (en) * | 1964-04-01 | 1967-09-05 | Ciba Geigy Corp | 3, 4-diphenyl-chromans |
CH471113A (de) * | 1965-01-29 | 1969-04-15 | Merck Ag E | Verfahren zur Herstellung von wasserlöslichen Flavanoidderivaten |
US3436393A (en) * | 1965-12-27 | 1969-04-01 | Parke Davis & Co | 4'-methoxy-2,2,4-trialkyl-delta**3-isoflavan compounds |
-
1966
- 1966-02-16 DE DE19661543749 patent/DE1543749A1/de active Pending
-
1967
- 1967-01-18 CH CH73167A patent/CH494222A/de not_active IP Right Cessation
- 1967-01-20 GB GB3175/67A patent/GB1103094A/en not_active Expired
- 1967-01-25 IL IL27321A patent/IL27321A/he unknown
- 1967-02-13 NL NL6702140A patent/NL6702140A/xx unknown
- 1967-02-13 US US615391A patent/US3535344A/en not_active Expired - Lifetime
- 1967-02-13 BE BE694025D patent/BE694025A/xx unknown
- 1967-02-13 FR FR94664A patent/FR6192M/fr not_active Expired
- 1967-02-14 DK DK80167AA patent/DK118611B/da unknown
- 1967-02-15 ES ES336869A patent/ES336869A1/es not_active Expired
- 1967-02-15 SE SE02111/67A patent/SE328301B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ES336869A1 (es) | 1968-05-01 |
FR6192M (he) | 1968-07-22 |
SE328301B (he) | 1970-09-14 |
GB1103094A (en) | 1968-02-14 |
CH494222A (de) | 1970-07-31 |
US3535344A (en) | 1970-10-20 |
DK118611B (da) | 1970-09-14 |
BE694025A (he) | 1967-08-14 |
DE1543749A1 (de) | 1969-12-11 |
NL6702140A (he) | 1967-08-17 |
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