IL272304B1 - תצמיד של נוגדן עם תרופה bcma מונוקלונלי - Google Patents
תצמיד של נוגדן עם תרופה bcma מונוקלונליInfo
- Publication number
- IL272304B1 IL272304B1 IL272304A IL27230420A IL272304B1 IL 272304 B1 IL272304 B1 IL 272304B1 IL 272304 A IL272304 A IL 272304A IL 27230420 A IL27230420 A IL 27230420A IL 272304 B1 IL272304 B1 IL 272304B1
- Authority
- IL
- Israel
- Prior art keywords
- antibody
- bcma
- seq
- amino acid
- acid sequence
- Prior art date
Links
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- C12N15/62—DNA sequences coding for fusion proteins
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- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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IL272304A IL272304A (he) | 2020-03-31 |
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IL272304A IL272304B2 (he) | 2017-08-01 | 2018-07-31 | תצמיד של נוגדן עם תרופה bcma מונוקלונלי |
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UA (1) | UA126813C2 (he) |
WO (1) | WO2019025983A1 (he) |
ZA (1) | ZA202001219B (he) |
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SG11201810327XA (en) | 2016-05-20 | 2018-12-28 | Harpoon Therapeutics Inc | Single domain serum albumin binding protein |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
WO2018160754A2 (en) | 2017-02-28 | 2018-09-07 | Harpoon Therapeutics, Inc. | Inducible monovalent antigen binding protein |
CA3063359A1 (en) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
TW202423990A (zh) * | 2017-08-01 | 2024-06-16 | 美商麥迪紐有限責任公司 | Bcma單株抗體-藥物結合物 |
JP7066837B2 (ja) | 2017-10-13 | 2022-05-13 | ハープーン セラピューティクス,インク. | B細胞成熟抗原結合タンパク質 |
PT3694529T (pt) | 2017-10-13 | 2024-09-20 | Harpoon Therapeutics Inc | Proteínas triespecíficas e métodos de utilização |
TWI838389B (zh) | 2018-07-19 | 2024-04-11 | 美商再生元醫藥公司 | 雙特異性抗-BCMAx抗-CD3抗體及其用途 |
WO2020069028A1 (en) | 2018-09-25 | 2020-04-02 | Harpoon Therapeutics, Inc. | Dll3 binding proteins and methods of use |
WO2020176549A1 (en) * | 2019-02-26 | 2020-09-03 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind bcma |
JP2022526738A (ja) | 2019-03-21 | 2022-05-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | アレルギーを治療するためのil-4/il-13経路阻害剤と形質細胞除去の組み合わせ |
SG11202112120WA (en) * | 2019-05-03 | 2021-11-29 | Celgene Corp | Anti-bcma antibody conjugate, compositions comprising the same, and methods of making and using the same |
KR20220016188A (ko) * | 2019-05-31 | 2022-02-08 | 메디뮨 엘엘씨 | 병용 요법 |
WO2021018168A1 (zh) * | 2019-07-30 | 2021-02-04 | 上海翰森生物医药科技有限公司 | 抗bcma抗体、其抗原结合片段及其医药用途 |
CN112409482B (zh) * | 2019-08-20 | 2022-08-26 | 杭州尚健生物技术有限公司 | Bcma抗体 |
CN115279781A (zh) * | 2020-03-26 | 2022-11-01 | 上海翰森生物医药科技有限公司 | 抗体药物偶联物及其医药用途 |
CN113637073B (zh) * | 2020-05-11 | 2024-04-12 | 上海赛比曼生物科技有限公司 | Bcma抗体及其制备和应用 |
CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
WO2022097047A1 (en) * | 2020-11-04 | 2022-05-12 | Medimmune, Llc | Treatment methods using anti-bcma antibody-drug conjugates |
CN114763383A (zh) * | 2021-01-13 | 2022-07-19 | 博生吉医药科技(苏州)有限公司 | 靶向人bcma的单克隆抗体及其应用 |
CN112812185B (zh) * | 2021-02-08 | 2022-01-18 | 华道(上海)生物医药有限公司 | 一种抗b细胞成熟抗原的单克隆抗体及其应用 |
EP4301418A1 (en) * | 2021-03-03 | 2024-01-10 | Sorrento Therapeutics, Inc. | Antibody-drug conjugates comprising an anti-bcma antibody |
JP2024519205A (ja) | 2021-04-30 | 2024-05-09 | セルジーン コーポレーション | 抗bcma抗体薬物コンジュゲート(adc)をガンマセクレターゼ阻害剤(gsi)と組み合わせて使用する併用療法 |
CN116745325A (zh) * | 2021-08-16 | 2023-09-12 | 上海优替济生生物医药有限公司 | Bcma靶向抗体、嵌合抗原受体及其应用 |
CN117980327A (zh) * | 2021-11-03 | 2024-05-03 | 杭州多禧生物科技有限公司 | 抗体的特异性偶联 |
CN117164714B (zh) * | 2023-10-08 | 2024-04-23 | 北京奇迈永华生物科技有限公司 | 一种靶向bcma的抗体及其应用 |
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