IL267540B - Glyceryl 3-hydroxybutyrates for migraine symptom management - Google Patents

Glyceryl 3-hydroxybutyrates for migraine symptom management

Info

Publication number
IL267540B
IL267540B IL267540A IL26754019A IL267540B IL 267540 B IL267540 B IL 267540B IL 267540 A IL267540 A IL 267540A IL 26754019 A IL26754019 A IL 26754019A IL 267540 B IL267540 B IL 267540B
Authority
IL
Israel
Prior art keywords
hydroxybutyrate
glyceryl
migraine
compound
tris
Prior art date
Application number
IL267540A
Other languages
English (en)
Hebrew (he)
Other versions
IL267540A (en
Inventor
Sami Hashim
Original Assignee
Neuroenergy Ventures Inc
Sami Hashim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neuroenergy Ventures Inc, Sami Hashim filed Critical Neuroenergy Ventures Inc
Publication of IL267540A publication Critical patent/IL267540A/en
Publication of IL267540B publication Critical patent/IL267540B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL267540A 2016-12-23 2017-11-30 Glyceryl 3-hydroxybutyrates for migraine symptom management IL267540B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/389,828 US20180177753A1 (en) 2016-12-23 2016-12-23 Glyceryl 3-hydroxybutyrates for migraine symptom management
PCT/US2017/063832 WO2018118369A1 (en) 2016-12-23 2017-11-30 Glyceryl 3-hydroxybutyrates for migraine symptom management

Publications (2)

Publication Number Publication Date
IL267540A IL267540A (en) 2019-08-29
IL267540B true IL267540B (en) 2022-07-01

Family

ID=62624821

Family Applications (1)

Application Number Title Priority Date Filing Date
IL267540A IL267540B (en) 2016-12-23 2017-11-30 Glyceryl 3-hydroxybutyrates for migraine symptom management

Country Status (13)

Country Link
US (2) US20180177753A1 (cg-RX-API-DMAC7.html)
EP (1) EP3558458B1 (cg-RX-API-DMAC7.html)
JP (1) JP7108320B2 (cg-RX-API-DMAC7.html)
KR (1) KR102390608B1 (cg-RX-API-DMAC7.html)
CN (1) CN110167637B (cg-RX-API-DMAC7.html)
BR (1) BR112019012431A2 (cg-RX-API-DMAC7.html)
CA (1) CA3046350C (cg-RX-API-DMAC7.html)
ES (1) ES2962879T3 (cg-RX-API-DMAC7.html)
IL (1) IL267540B (cg-RX-API-DMAC7.html)
MX (1) MX389468B (cg-RX-API-DMAC7.html)
MY (1) MY190308A (cg-RX-API-DMAC7.html)
PT (1) PT3558458T (cg-RX-API-DMAC7.html)
WO (1) WO2018118369A1 (cg-RX-API-DMAC7.html)

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US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
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US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
EP3880650B1 (de) * 2019-01-17 2023-09-06 KetoLipix Therapeutics GmbH Verfahren zur herstellung von struktureinheiten auf basis von glyceriden von hydroxycarbonsäuren enthaltenden lipiden
CN113329990B (zh) * 2019-01-17 2024-06-07 凯托利皮克斯治疗有限责任公司 羟基羧酸甘油酯的生产方法
BR112021017954A2 (pt) 2019-03-14 2021-11-16 Neuroenergy Ventures Inc Formulação de mascaramento de sabor para compostos de corpo cetônico
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
WO2020242478A1 (en) * 2019-05-30 2020-12-03 Neuroenergy Ventures, Inc. Glyceryl tris (beta-hydroxybutyrate) and neuronal transient ischemic attacks
US20250197566A1 (en) * 2019-06-12 2025-06-19 Ioi Oleo Gmbh Process for preparing polyol-based esters of acyl-capped hydroxy carboxylic acids
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
IT201900018491A1 (it) * 2019-10-10 2021-04-10 Dr Schaer S P A Procedimento di purificazione del tris-(3-idrossibutirrato)-gliceril estere
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US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
AU2022387742A1 (en) * 2021-11-12 2024-06-27 Arxada Ag Polyol-derived compounds
US20250002446A1 (en) * 2021-11-26 2025-01-02 Arxada Ag Acetoacetate Based Ketals
US20240299548A1 (en) * 2022-01-18 2024-09-12 Today, Inc. Molecules, formulations, and methods for nutritional support of athletes, patients, and others
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Also Published As

Publication number Publication date
CA3046350A1 (en) 2018-06-28
JP7108320B2 (ja) 2022-07-28
BR112019012431A2 (pt) 2020-04-14
EP3558458B1 (en) 2023-10-18
US10792269B2 (en) 2020-10-06
MX2019006844A (es) 2019-08-16
US20180177753A1 (en) 2018-06-28
PT3558458T (pt) 2023-11-27
MY190308A (en) 2022-04-13
EP3558458A1 (en) 2019-10-30
WO2018118369A1 (en) 2018-06-28
CN110167637A (zh) 2019-08-23
KR102390608B1 (ko) 2022-04-25
CA3046350C (en) 2022-08-16
CN110167637B (zh) 2023-03-14
KR20190099465A (ko) 2019-08-27
EP3558458A4 (en) 2020-08-12
IL267540A (en) 2019-08-29
JP2020502250A (ja) 2020-01-23
ES2962879T3 (es) 2024-03-21
MX389468B (es) 2025-03-20
US20190117612A1 (en) 2019-04-25

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