IL261146B - Methods and compositions for treating cancers and neoplasms - Google Patents

Methods and compositions for treating cancers and neoplasms

Info

Publication number
IL261146B
IL261146B IL261146A IL26114618A IL261146B IL 261146 B IL261146 B IL 261146B IL 261146 A IL261146 A IL 261146A IL 26114618 A IL26114618 A IL 26114618A IL 261146 B IL261146 B IL 261146B
Authority
IL
Israel
Prior art keywords
asc
cells
cancer
cell
tumor
Prior art date
Application number
IL261146A
Other languages
English (en)
Hebrew (he)
Other versions
IL261146A (en
Inventor
Gilert Ariel
Yissachar Allen Hoshea
SHRAGA HELED Niva
Ofir Rachel
Aberman Zami
Original Assignee
Pluristem Ltd
Gilert Ariel
Yissachar Allen Hoshea
SHRAGA HELED Niva
Ofir Rachel
Aberman Zami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pluristem Ltd, Gilert Ariel, Yissachar Allen Hoshea, SHRAGA HELED Niva, Ofir Rachel, Aberman Zami filed Critical Pluristem Ltd
Publication of IL261146A publication Critical patent/IL261146A/en
Publication of IL261146B publication Critical patent/IL261146B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062General methods for three-dimensional culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL261146A 2016-02-18 2017-02-16 Methods and compositions for treating cancers and neoplasms IL261146B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662296621P 2016-02-18 2016-02-18
PCT/IB2017/050868 WO2017141181A1 (en) 2016-02-18 2017-02-16 Methods and compositions for treating cancers and neoplasms

Publications (2)

Publication Number Publication Date
IL261146A IL261146A (en) 2018-10-31
IL261146B true IL261146B (en) 2022-07-01

Family

ID=58266008

Family Applications (1)

Application Number Title Priority Date Filing Date
IL261146A IL261146B (en) 2016-02-18 2017-02-16 Methods and compositions for treating cancers and neoplasms

Country Status (7)

Country Link
US (1) US20210205370A1 (enExample)
EP (1) EP3416662B1 (enExample)
JP (1) JP6884792B2 (enExample)
AU (1) AU2017220148A1 (enExample)
CA (1) CA3012741A1 (enExample)
IL (1) IL261146B (enExample)
WO (1) WO2017141181A1 (enExample)

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SG10202111394XA (en) 2017-04-13 2021-12-30 Senti Biosciences Inc Combinatorial cancer immunotherapy
US20210000882A1 (en) * 2018-02-28 2021-01-07 Crown Scientific, LLC Production and use of extracellular vesicles
US20210115395A1 (en) * 2018-03-28 2021-04-22 Pluristem Ltd. Methods for expanding adherent stromal cells and cells obtained thereby
CA3098514A1 (en) * 2018-04-30 2019-11-14 Children's Medical Center Corporation Mesenchymal stromal cell exosomes and uses thereof
AU2019359890B2 (en) * 2018-10-17 2024-10-24 Senti Biosciences, Inc. Combinatorial cancer immunotherapy
US11419898B2 (en) 2018-10-17 2022-08-23 Senti Biosciences, Inc. Combinatorial cancer immunotherapy
EP4031145A4 (en) * 2019-09-06 2023-07-26 Mantra Bio, Inc. EXTRACELLULAR VESICLE FENRETINIDE COMPOSITIONS, EXTRACELLULAR VESICLE C-KIT INHIBITOR COMPOSITIONS, METHOD OF PREPARATION AND USES THEREOF
EP4214714A4 (en) * 2020-09-21 2024-10-16 Mestastop Solutions Private Limited SYSTEMS AND METHODS FOR PREDICTING CANCER METASTASIS AND DRUG SCREENING
KR20240047474A (ko) * 2021-09-27 2024-04-12 비타스프링 바이오메디컬 컴퍼니 리미티드. 탈락막 태반 중간엽 줄기 세포 및 혈관형성을 촉진시키기 위한 약제학적 조성물의 제조에서의 이의 용도

Citations (4)

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WO2008019148A2 (en) * 2006-08-04 2008-02-14 Anthrogenesis Corporation Tumor suppression using placental stem cells
WO2009045360A2 (en) * 2007-09-28 2009-04-09 Celgene Cellular Therapeutics Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
WO2010026575A2 (en) * 2008-09-02 2010-03-11 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
WO2011094181A1 (en) * 2010-01-26 2011-08-04 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells

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US5629186A (en) 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US6132463A (en) 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
ATE227338T1 (de) 1998-03-18 2002-11-15 Massachusetts Inst Technology Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
EP1261694B1 (en) 2000-02-26 2008-01-16 Artecel, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
WO2007011693A2 (en) * 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
ES2537641T3 (es) 2006-03-23 2015-06-10 Pluristem Ltd. Métodos de expansión celular y usos de células y medios acondicionados producidos de este modo para terapia
WO2011132087A1 (en) * 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
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CN107028981B (zh) * 2007-09-19 2021-04-20 普拉里斯坦有限公司 来自脂肪或胎盘组织的粘附细胞及其在治疗中的用途
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Publication number Priority date Publication date Assignee Title
WO2008019148A2 (en) * 2006-08-04 2008-02-14 Anthrogenesis Corporation Tumor suppression using placental stem cells
WO2009045360A2 (en) * 2007-09-28 2009-04-09 Celgene Cellular Therapeutics Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
WO2010026575A2 (en) * 2008-09-02 2010-03-11 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
WO2011094181A1 (en) * 2010-01-26 2011-08-04 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GONZ?LEZ, PAZ L., ET AL., CHORION MESENCHYMAL STEM CELLS SHOW SUPERIOR DIFFERENTIATION, IMMUNOSUPPRESSIVE, AND ANGIOGENIC POTENTIALS IN COMPARISON WITH HAPLOIDENTICAL MATERNAL PLACENTAL CELLS., 13 August 2015 (2015-08-13) *
SPEES, JEFFREY L., RYANG HWA LEE, AND CARL A. GREGORY., MECHANISMS OF MESENCHYMAL STEM/STROMAL CELL FUNCTION., 31 August 2016 (2016-08-31) *

Also Published As

Publication number Publication date
EP3416662A1 (en) 2018-12-26
EP3416662B1 (en) 2020-07-29
JP2019509999A (ja) 2019-04-11
US20210205370A1 (en) 2021-07-08
AU2017220148A1 (en) 2018-07-19
IL261146A (en) 2018-10-31
CA3012741A1 (en) 2017-08-24
JP6884792B2 (ja) 2021-06-09
WO2017141181A1 (en) 2017-08-24

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